Roscovitine inhibits EBNA1 serine 393 phosphorylation, nuclear localization, transcription, and episome maintenance
about
Epstein-Barr Virus: Diseases Linked to Infection and TransformationEpstein-Barr virus latent genesCRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent InfectionsDeciphering fact from artifact when using reporter assays to investigate the roles of host factors on L1 retrotranspositionAssay Development and High-Throughput Screening for Inhibitors of Kaposi's Sarcoma-Associated Herpesvirus N-Terminal Latency-Associated Nuclear Antigen Binding to Nucleosomes.The AT-hook DNA binding ability of the Epstein Barr virus EBNA1 protein is necessary for the maintenance of viral genomes in latently infected cells.Targeted disruption of EBNA1 in EBV-infected cells attenuated cell growth.ERK2 phosphorylation of EBNA1 serine 383 residue is important for EBNA1-dependent transactivationSmall molecule inhibition of Epstein-Barr virus nuclear antigen-1 DNA binding activity interferes with replication and persistence of the viral genome.Epigenetic regulation of EBV and KSHV latencyPotential of protein kinase inhibitors for treating herpesvirus-associated disease.Identification of a novel protein interaction motif in the regulatory subunit of casein kinase 2.Efficient replication of Epstein-Barr virus-derived plasmids requires tethering by EBNA1 to host chromosomes.DNA ligand designed to antagonize EBNA1 represses Epstein-Barr virus-induced immortalization.Computational analysis of EBNA1 "druggability" suggests novel insights for Epstein-Barr virus inhibitor design.Epstein-Barr virus (EBV) provides survival factors to EBV+ diffuse large B-cell lymphoma (DLBCL) lines and modulates cytokine induced specific chemotaxis in EBV+ DLBCL.
P2860
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P2860
Roscovitine inhibits EBNA1 serine 393 phosphorylation, nuclear localization, transcription, and episome maintenance
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Roscovitine inhibits EBNA1 ser ...... ption, and episome maintenance
@ast
Roscovitine inhibits EBNA1 ser ...... ption, and episome maintenance
@en
type
label
Roscovitine inhibits EBNA1 ser ...... ption, and episome maintenance
@ast
Roscovitine inhibits EBNA1 ser ...... ption, and episome maintenance
@en
prefLabel
Roscovitine inhibits EBNA1 ser ...... ption, and episome maintenance
@ast
Roscovitine inhibits EBNA1 ser ...... ption, and episome maintenance
@en
P2093
P2860
P356
P1433
P1476
Roscovitine inhibits EBNA1 ser ...... ption, and episome maintenance
@en
P2093
Angela N Koehler
Eun Kyung Lee
Myung-Soo Kang
Timothy A Lewis
Vishal Soni
Viswanathan Srinivasan
P2860
P304
P356
10.1128/JVI.01628-10
P577
2011-01-05T00:00:00Z