Chlamydia muridarum T-cell antigens formulated with the adjuvant DDA/TDB induce immunity against infection that correlates with a high frequency of gamma interferon (IFN-gamma)/tumor necrosis factor alpha and IFN-gamma/interleukin-17 double-positive
about
Tissue-Resident T Cells as the Central Paradigm of Chlamydia ImmunityChlamydial polymorphic membrane proteins: regulation, function and potential vaccine candidatesChlamydia trachomatis Genital Infections.A T cell epitope-based vaccine protects against chlamydial infection in HLA-DR4 transgenic mice.Simultaneous Subcutaneous and Intranasal Administration of a CAF01-Adjuvanted Chlamydia Vaccine Elicits Elevated IgA and Protective Th1/Th17 Responses in the Genital Tract.Chlamydial protease-like activity factor mediated protection against C. trachomatis in guinea pigsImmunization of a wild koala population with a recombinant Chlamydia pecorum Major Outer Membrane Protein (MOMP) or Polymorphic Membrane Protein (PMP) based vaccine: New insights into immune response, protection and clearanceCoadministration of polyinosinic:polycytidylic acid and immunostimulatory complexes modifies antigen processing in dendritic cell subsets and enhances HIV gag-specific T cell immunity.Evaluation of a multisubunit recombinant polymorphic membrane protein and major outer membrane protein T cell vaccine against Chlamydia muridarum genital infection in three strains of mice.Immunization with a combination of integral chlamydial antigens and a defined secreted protein induces robust immunity against genital chlamydial challenge.CD4+ T cells and antibody are required for optimal major outer membrane protein vaccine-induced immunity to Chlamydia muridarum genital infection.Identification of immunodominant antigens by probing a whole Chlamydia trachomatis open reading frame proteome microarray using sera from immunized mice.Development of a Chlamydia trachomatis T cell Vaccine.Immunization with a MOMP-based vaccine protects mice against a pulmonary Chlamydia challenge and identifies a disconnection between infection and pathologyInterleukin-17 contributes to generation of Th1 immunity and neutrophil recruitment during Chlamydia muridarum genital tract infection but is not required for macrophage influx or normal resolution of infectionVaccination against Chlamydia genital infection utilizing the murine C. muridarum model.Immunization with live and dead Chlamydia muridarum induces different levels of protective immunity in a murine genital tract model: correlation with MHC class II peptide presentation and multifunctional Th1 cells.The duration of Chlamydia muridarum genital tract infection and associated chronic pathological changes are reduced in IL-17 knockout mice but protection is not increased further by immunization.B cells enhance antigen-specific CD4 T cell priming and prevent bacteria dissemination following Chlamydia muridarum genital tract infection.The requirement for potent adjuvants to enhance the immunogenicity and protective efficacy of protein vaccines can be overcome by prior immunization with a recombinant adenovirusOuter membrane proteins preferentially load MHC class II peptides: implications for a Chlamydia trachomatis T cell vaccine.Plac8-dependent and inducible NO synthase-dependent mechanisms clear Chlamydia muridarum infections from the genital tractFrequency of Chlamydia trachomatis-specific T cell interferon-γ and interleukin-17 responses in CD4-enriched peripheral blood mononuclear cells of sexually active adolescent females.Chlamydia muridarum T cell antigens and adjuvants that induce protective immunity in micePmpG303-311, a protective vaccine epitope that elicits persistent cellular immune responses in Chlamydia muridarum-immune mice.Vaccine-induced th17 cells are maintained long-term postvaccination as a distinct and phenotypically stable memory subset.Different human vaccine adjuvants promote distinct antigen-independent immunological signatures tailored to different pathogensA multi-subunit Chlamydia vaccine inducing neutralizing antibodies and strong IFN-γ⁺ CMI responses protects against a genital infection in minipigsProteomic identification of immunodominant chlamydial antigens in a mouse modelImmunization with apical membrane antigen 1 confers sterile infection-blocking immunity against Plasmodium sporozoite challenge in a rodent model.IFNγ is Required for Optimal Antibody-Mediated Immunity against Genital Chlamydia Infection.Trehalose diester glycolipids are superior to the monoesters in binding to Mincle, activation of macrophages in vitro and adjuvant activity in vivoAssessment of the role in protection and pathogenesis of the Chlamydia muridarum V-type ATP synthase subunit A (AtpA) (TC0582).A Protective Vaccine against Chlamydia Genital Infection Using Vault Nanoparticles without an Added Adjuvant.Towards a Chlamydia trachomatis vaccine: how close are we?CCR7 Deficiency Allows Accelerated Clearance of Chlamydia from the Female Reproductive Tract.Comparison of the nine polymorphic membrane proteins of Chlamydia trachomatis for their ability to induce protective immune responses in mice against a C. muridarum challenge.Update on Chlamydia trachomatis Vaccinology.Respective IL-17A production by γδ T and Th17 cells and its implication in host defense against chlamydial lung infection.Identification of Chlamydia trachomatis Antigens Recognized by T Cells From Highly Exposed Women Who Limit or Resist Genital Tract Infection.
P2860
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P2860
Chlamydia muridarum T-cell antigens formulated with the adjuvant DDA/TDB induce immunity against infection that correlates with a high frequency of gamma interferon (IFN-gamma)/tumor necrosis factor alpha and IFN-gamma/interleukin-17 double-positive
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
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2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
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2010年論文
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2010年论文
@wuu
name
Chlamydia muridarum T-cell ant ...... interleukin-17 double-positive
@ast
Chlamydia muridarum T-cell ant ...... interleukin-17 double-positive
@en
type
label
Chlamydia muridarum T-cell ant ...... interleukin-17 double-positive
@ast
Chlamydia muridarum T-cell ant ...... interleukin-17 double-positive
@en
prefLabel
Chlamydia muridarum T-cell ant ...... interleukin-17 double-positive
@ast
Chlamydia muridarum T-cell ant ...... interleukin-17 double-positive
@en
P2093
P2860
P356
P1476
Chlamydia muridarum T-cell ant ...... interleukin-17 double-positive
@en
P2093
Caixia Shen
Janina Jiang
Karuna P Karunakaran
Nicole L Rosin
Robert C Brunham
Xiaozhou Jiang
P2860
P304
P356
10.1128/IAI.01374-09
P407
P577
2010-03-15T00:00:00Z