Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding. - Wikidata - thesis-toulmin - TriplyDB

Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding.

Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding.

http://www.wikidata.org/entity/Q33839575

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Mechanisms of cohesin-mediated gene regulation and lessons learned from cohesinopathies A cell cycle role for the epigenetic factor CTCF-L/BORIS DNA topoisomerase II modulates insulator function in Drosophila Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence code The p53 circuit board Transcription of angiogenin and ribonuclease 4 is regulated by RNA polymerase III elements and a CCCTC binding factor (CTCF)-dependent intragenic chromatin loop.Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter.Epigenetic repression of RARRES1 is mediated by methylation of a proximal promoter and a loss of CTCF binding.Homozygous mdm2 SNP309 cancer cells with compromised transcriptional elongation at p53 target genes are sensitive to induction of p53-independent cell death.Disparate chromatin landscapes and kinetics of inactivation impact differential regulation of p53 target genes Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development Interactions of chromatin context, binding site sequence content, and sequence evolution in stress-induced p53 occupancy and transactivation.Harnessing the p53-PUMA axis to overcome DNA damage resistance in renal cell carcinoma Genome-wide targeting of the epigenetic regulatory protein CTCF to gene promoters by the transcription factor TFII-I.Phosphorylation of Tip60 by p38α regulates p53-mediated PUMA induction and apoptosis in response to DNA damage Effects of RNA interference-mediated gene silencing of JMJD2A on human breast cancer cell line MDA-MB-231 in vitro.Human papillomaviruses activate and recruit SMC1 cohesin proteins for the differentiation-dependent life cycle through association with CTCF insulators A chromatin code for alternative splicing involving a putative association between CTCF and HP1α proteins Whole-genome cartography of p53 response elements ranked on transactivation potential.Rhein Elicits In Vitro Cytotoxicity in Primary Human Liver HL-7702 Cells by Inducing Apoptosis through Mitochondria-Mediated Pathway.De-SUMOylation of CCCTC binding factor (CTCF) in hypoxic stress-induced human corneal epithelial cells.Epigenetic silencing of miR-181c by DNA methylation in glioblastoma cell lines.A Chromatin-Focused siRNA Screen for Regulators of p53-Dependent Transcription.The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3.High-Resolution 4C Reveals Rapid p53-Dependent Chromatin Reorganization of the CDKN1A Locus in Response to Stress.Effects of siRNA-mediated knockdown of jumonji domain containing 2A on proliferation, migration and invasion of the human breast cancer cell line MCF-7 Elba, a novel developmentally regulated chromatin boundary factor is a hetero-tripartite DNA binding complex.Developmentally programmed 3' CpG island methylation confers tissue- and cell-type-specific transcriptional activation The SMC1-SMC3 cohesin heterodimer structures DNA through supercoiling-dependent loop formation.Human pregnane X receptor compromises the function of p53 and promotes malignant transformation Effects of low doses of ionizing radiation exposures on stress-responsive gene expression in human embryonic stem cells.EZH2-mediated Puma gene repression regulates non-small cell lung cancer cell proliferation and cisplatin-induced apoptosis.Cohesin: a critical chromatin organizer in mammalian gene regulation CTCF, cohesin, and histone variants: connecting the genome.Temporal Dissection of Rate Limiting Transcriptional Events Using Pol II ChIP and RNA Analysis of Adrenergic Stress Gene Activation.A Scalable Epitope Tagging Approach for High Throughput ChIP-Seq Analysis.Disruption of CTCF/cohesin-mediated high-order chromatin structures by DNA methylation downregulates PTGS2 expression.Mammalian cells acquire epigenetic hallmarks of human cancer during immortalization.Stress-induced expression of p53 target genes is insensitive to SNW1/SKIP downregulation.An insulator embedded in the chicken α-globin locus regulates chromatin domain configuration and differential gene expression.

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P2860

Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding.

http://www.wikidata.org/entity/Q33839575

description

2010 nî lūn-bûn

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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի մայիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

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2010年論文

@zh-tw

2010年论文

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name

Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding.

@ast

Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding.

@en

type

label

Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding.

@ast

Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding.

@en

prefLabel

Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding.

@ast

Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding.

@en

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Genes & Development

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Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding

@en

P2093

Joaquín M Espinosa

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P2860

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

PUMA induces the rapid apoptosis of colorectal cancer cells

PUMA, a novel proapoptotic gene, is induced by p53

ASPP proteins specifically stimulate the apoptotic function of p53

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator

CTCF physically links cohesin to chromatin

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

hCAS/CSE1L associates with chromatin and regulates expression of select p53 target genes

PUMA mediates the apoptotic response to p53 in colorectal cancer cells

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1022-1034

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scholarly article

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10.1101/GAD.1881010

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10

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24

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2010-05-01T00:00:00Z

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44608005

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20478995

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2867207

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