Suppression of angiogenesis and tumor growth by the inhibitor K1-5 generated by plasmin-mediated proteolysis.
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Residues essential for plasminogen binding by the cation-independent mannose 6-phosphate receptorThe angiogenesis inhibitor protease-activated kringles 1-5 reduces the severity of murine collagen-induced arthritisGrowth factors in corneal wound healing following refractive surgery: A review.Purification and characterization of A61. An angiostatin-like plasminogen fragment produced by plasmin autodigestion in the absence of sulfhydryl donors.Vasculostatin, a proteolytic fragment of brain angiogenesis inhibitor 1, is an antiangiogenic and antitumorigenic factor.Plasmid transfer of plasminogen K1-5 reduces subcutaneous hepatoma growth by affecting inflammatory factorsNew vessels, new approaches: angiogenesis as a therapeutic target in musculoskeletal disorders.Local endostatin treatment of gliomas administered by microencapsulated producer cells.Matrix metalloproteinase-19 inhibits growth of endothelial cells by generating angiostatin-like fragments from plasminogen.The hemostatic system and angiogenesis in malignancy.Adiponectin in relation to childhood myeloblastic leukaemia.Adiponectin: a link between obesity and cancer.Cellular actions and signaling by endostatin.Isolation and purification of recombinant human plasminogen Kringle 5 by liquid chromatography and ammonium sulfate salting-out.Angiostatic effects of NK cell-derived IFN-γ counteracted by tumour cell Bcl-xL expression.Inhibition of tumor angiogenesis by angiostatin: from recombinant protein to gene therapy.Gene transfer for the treatment of neovascular ocular disease (an American Ophthalmological Society thesis).Leptin induces vascular permeability and synergistically stimulates angiogenesis with FGF-2 and VEGF.Angiogenic factors FGF2 and PDGF-BB synergistically promote murine tumor neovascularization and metastasis.Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis.The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophagesVEGF significantly restores impaired memory behavior in Alzheimer's mice by improvement of vascular survivalA novel peptide from human apolipoprotein(a) inhibits angiogenesis and tumor growth by targeting c-Src phosphorylation in VEGF-induced human umbilical endothelial cells.Gene therapy for bladder cancer using E1B-55 kD-deleted adenovirus in combination with adenoviral vector encoding plasminogen kringles 1-5.Mediators of ocular angiogenesis.Traditional Chinese medicine: a treasured natural resource of anticancer drug research and development.A truncated plasminogen activator inhibitor-1 protein blocks the availability of heparin-binding vascular endothelial growth factor A isoforms.Plasminogen derivatives encoding kringles 1-4 and kringles 1-5 exert indirect antiangiogenic and direct antitumoral effects in experimental lung cancer.Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR2.Plasminogen fragment K1-5 improves survival in a murine hepatocellular carcinoma model.Specific conformational changes of plasminogen induced by chloride ions, 6-aminohexanoic acid and benzamidine, but not the overall openness of plasminogen regulate, production of biologically active angiostatins.Cotargeting tumor and tumor endothelium effectively inhibits the growth of human prostate cancer in adenovirus-mediated antiangiogenesis and oncolysis combination therapy.A gene therapy for cancer based on the angiogenesis inhibitor, vasostatin.Human placenta mesenchymal stem cells expressing exogenous kringle1-5 protein by fiber-modified adenovirus suppress angiogenesis.Treatment of colorectal and hepatocellular carcinomas by adenoviral mediated gene transfer of endostatin and angiostatin-like molecule in mice.Specific interaction of angiostatin with integrin alpha(v)beta(3) in endothelial cells.Plasmin reduction by phosphoglycerate kinase is a thiol-independent process.Phosphorylation of pyrimidine L-deoxynucleoside analog diphosphates. Kinetics of phosphorylation and dephosphorylation of nucleoside analog diphosphates and triphosphates by 3-phosphoglycerate kinase.Upregulation of Cdc2 and cyclin A during apoptosis of endothelial cells induced by cleaved high-molecular-weight kininogen.Bacillolysin MA, a novel bacterial metalloproteinase that produces angiostatin-like fragments from plasminogen and activates protease zymogens in the coagulation and fibrinolysis systems.
P2860
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P2860
Suppression of angiogenesis and tumor growth by the inhibitor K1-5 generated by plasmin-mediated proteolysis.
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Suppression of angiogenesis an ...... plasmin-mediated proteolysis.
@ast
Suppression of angiogenesis an ...... plasmin-mediated proteolysis.
@en
type
label
Suppression of angiogenesis an ...... plasmin-mediated proteolysis.
@ast
Suppression of angiogenesis an ...... plasmin-mediated proteolysis.
@en
prefLabel
Suppression of angiogenesis an ...... plasmin-mediated proteolysis.
@ast
Suppression of angiogenesis an ...... plasmin-mediated proteolysis.
@en
P2093
P2860
P356
P1476
Suppression of angiogenesis an ...... plasmin-mediated proteolysis.
@en
P2093
N Veitonmäki
P2860
P304
P356
10.1073/PNAS.96.10.5728
P407
P577
1999-05-01T00:00:00Z