SUMO1 modification stabilizes CDK6 protein and drives the cell cycle and glioblastoma progression.
about
SUMOylation-Mediated Regulation of Cell Cycle Progression and CancerTargeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitorsNGX6a is degraded through a proteasome-dependent pathway without ubiquitination mediated by ezrin, a cytoskeleton-membrane linkerHigh-level SAE2 promotes malignant phenotype and predicts outcome in gastric cancer.Knockdown of SUMO-activating enzyme subunit 2 (SAE2) suppresses cancer malignancy and enhances chemotherapy sensitivity in small cell lung cancer.IRTKS negatively regulates antiviral immunity through PCBP2 sumoylation-mediated MAVS degradation.A gene-expression screen identifies a non-toxic sumoylation inhibitor that mimics SUMO-less human LRH-1 in liver.SUMOylated MAFB promotes colorectal cancer tumorigenesis.Detailed longitudinal sampling of glioma stem cells in situ reveals Chr7 gain and Chr10 loss as repeated events in primary tumor formation and recurrence.SUMO and the robustness of cancer.Regulation of Cellular Processes by SUMO: Understudied Topics.Resetting cancer stem cell regulatory nodes upon MYC inhibition.Exploration of Involved Key Genes and Signaling Diversity in Brain Tumors.UBC9-Mediated Sumoylation Favorably Impacts Cardiac Function in Compromised HeartsNDGA-P21, a novel derivative of nordihydroguaiaretic acid, inhibits glioma cell proliferation and stemness.The Key Regulator for Language and Speech Development, FOXP2, is a Novel Substrate for SUMOylation.Topotecan is a potent inhibitor of SUMOylation in glioblastoma multiforme and alters both cellular replication and metabolic programming.Sumoylation in p27kip1 via RanBP2 promotes cancer cell growth in cholangiocarcinoma cell line QBC939.Post-translational modifications of Arabidopsis E3 SUMO ligase AtSIZ1 are controlled by environmental conditions.H19 derived microRNA-675 regulates cell proliferation and migration through CDK6 in glioma.SUMOylation of Rb enhances its binding with CDK2 and phosphorylation at early G1 phase.SUMOylation controls stem cell proliferation and regional cell death through Hedgehog signaling in planarians.Protein SUMOylation modification and its associations with disease.Proteogenomic characterization and integrative analysis of glioblastoma multiforme.The Arabidopsis SUMO E3 ligase AtMMS21 dissociates the E2Fa/DPa complex in cell cycle regulation.A New Way to Treat Brain Tumors: Targeting Proteins Coded by Microcephaly Genes?: Brain tumors and microcephaly arise from opposing derangements regulating progenitor growth. Drivers of microcephaly could be attractive brain tumor targets.The post-translational modification, SUMOylation, and cancer (Review).High-level SAE2 promotes malignant phenotype and predicts outcome in gastric cancerSUMO-Mediated Regulation of Nuclear Functions and Signaling Processes
P2860
Q26776081-039CE042-6EDF-479D-8156-993DF83AE6C5Q26827580-63E995DC-41A3-409B-9F25-42F93DE494E9Q34774429-1D00D07A-90D9-40E5-A666-EA05694F935BQ34991201-A6B07C07-1B3E-404D-9541-2F7D7188411DQ35789345-A3AC48BE-B59B-4B9A-8B9D-878B2B7AA57BQ36059366-72C643DB-9E8E-4C74-BBAB-E31A104ACA90Q36567950-73553EF7-029F-4558-A9D4-88D3CB0D73EBQ37696334-7073061A-3994-487E-A1F4-BF111638EBCAQ38677899-2778541E-09C4-4A3A-BA10-D3511F774DFBQ39108925-DD19A4BB-57D4-47B0-AA7A-A18C2AF6FA06Q39136000-B991D45F-C749-4C90-8E46-F9C946D73F85Q39182602-ED3A0C38-4D9E-41FD-BDE6-10468937FB5CQ39298204-82C62AB7-412A-4A9B-9F2B-2ACEA7C8BDC9Q39798030-DE64B9DE-6409-478C-B4D1-D24F46893089Q40201358-C02B906D-8758-4D6A-8CE3-C4F27BBA22C0Q40694675-36D405B9-7C44-421D-A5D6-302276F132E3Q41287854-F81C0175-EE0D-4975-9D34-3C8F0F98AC52Q41525898-02B9EF36-743E-4EEA-ABF2-06CEDA58C55EQ41878371-01290478-1A78-4BAC-B66B-96E6F3AD4FD2Q42239876-0C898911-13E3-4159-9471-7D04ADC44DCAQ42408048-8BAB0C81-A61E-41A6-9507-E871BE430998Q46311411-4ED23CCC-3842-4F6A-AE40-51465212A465Q47099041-F13173D3-A6F0-4A90-B2C8-6EFDEB18EF6DQ47099919-DB01A9C1-B3AC-448E-944C-61205F41D7DCQ51593619-B9EB7F40-5A5F-4E4D-9AD3-DF8B56FB1925Q52690166-07DD37A8-250A-4CCF-91B9-5962688AF810Q52730181-959749AF-C617-42F1-9CDF-348A7420E051Q56511335-F38CEC3B-AF13-4168-A270-40695B9D3F3BQ58803049-A77E3FEC-A23D-44EC-B999-B7CCEEE8E17C
P2860
SUMO1 modification stabilizes CDK6 protein and drives the cell cycle and glioblastoma progression.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
SUMO1 modification stabilizes ...... and glioblastoma progression.
@ast
SUMO1 modification stabilizes ...... and glioblastoma progression.
@en
type
label
SUMO1 modification stabilizes ...... and glioblastoma progression.
@ast
SUMO1 modification stabilizes ...... and glioblastoma progression.
@en
prefLabel
SUMO1 modification stabilizes ...... and glioblastoma progression.
@ast
SUMO1 modification stabilizes ...... and glioblastoma progression.
@en
P2093
P2860
P356
P1476
SUMO1 modification stabilizes ...... and glioblastoma progression.
@en
P2093
Anita C Bellail
Chunhai Hao
Jeffrey J Olson
P2860
P2888
P356
10.1038/NCOMMS5234
P407
P577
2014-06-23T00:00:00Z
P5875
P6179
1020527604