DNA damage responses by human ELG1 in S phase are important to maintain genomic integrity. - Wikidata - thesis-toulmin - TriplyDB

DNA damage responses by human ELG1 in S phase are important to maintain genomic integrity.

DNA damage responses by human ELG1 in S phase are important to maintain genomic integrity.

http://www.wikidata.org/entity/Q33894479

about

Predisposition to cancer caused by genetic and functional defects of mammalian Atad5 Genome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity.Elg1, an alternative subunit of the RFC clamp loader, preferentially interacts with SUMOylated PCNA.A genetic screen based on in vivo RNA imaging reveals centrosome-independent mechanisms for localizing gurken transcripts in Drosophila Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through Its interactions with PCNA and USP1.Bridge-induced chromosome translocation in yeast relies upon a Rad54/Rdh54-dependent, Pol32-independent pathway Myelodysplasia in autosomal dominant and sporadic monocytopenia immunodeficiency syndrome: diagnostic features and clinical implications.Multiple facets of histone variant H2AX: a DNA double-strand-break marker with several biological functions.Dynamic regulation of PCNA ubiquitylation/deubiquitylation.Identification of six new susceptibility loci for invasive epithelial ovarian cancer.Endogenous DNA replication stress results in expansion of dNTP pools and a mutator phenotype High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.Cell-based high-throughput screens for the discovery of chemotherapeutic agents.Hepatitis B Virus X Protein Upregulates hELG1/ ATAD5 Expression through E2F1 in Hepatocellular Carcinoma.ATAD5 regulates the lifespan of DNA replication factories by modulating PCNA level on the chromatin.The Enok acetyltransferase complex interacts with Elg1 and negatively regulates PCNA unloading to promote the G1/S transition Is PCNA unloading the central function of the Elg1/ATAD5 replication factor C-like complex?Histone deacetylase inhibitors selectively target homology dependent DNA repair defective cells and elevate non-homologous endjoining activity.Emerging genotype-phenotype relationships in patients with large NF1 deletions.The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability.Deubiquitylating enzymes and DNA damage response pathways.Control of Genome Integrity by RFC Complexes; Conductors of PCNA Loading onto and Unloading from Chromatin during DNA Replication.Alternative replication factor C protein, Elg1, maintains chromosome stability by regulating PCNA levels on chromatin.Regulation of Elg1 activity by phosphorylation.Genetic and physical interactions between the yeast ELG1 gene and orthologs of the Fanconi anemia pathway.DNA replication factor C1 mediates genomic stability and transcriptional gene silencing in Arabidopsis.SHPRH regulates rRNA transcription by recognizing the histone code in an mTOR-dependent manner.

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DNA damage responses by human ELG1 in S phase are important to maintain genomic integrity.

http://www.wikidata.org/entity/Q33894479

description

2009 nî lūn-bûn

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2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

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2009年論文

@zh-tw

2009年论文

@wuu

name

DNA damage responses by human ...... to maintain genomic integrity.

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DNA damage responses by human ...... to maintain genomic integrity.

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type

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DNA damage responses by human ...... to maintain genomic integrity.

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DNA damage responses by human ...... to maintain genomic integrity.

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DNA damage responses by human ...... to maintain genomic integrity.

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DNA damage responses by human ...... to maintain genomic integrity.

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DNA damage responses by human ...... to maintain genomic integrity.

@en

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Amalia Dutra

http://www.w3.org/2001/XMLSchema#string

Evgenia Pak

http://www.w3.org/2001/XMLSchema#string

Koji Nakanishi

http://www.w3.org/2001/XMLSchema#string

Kyoo-young Lee

http://www.w3.org/2001/XMLSchema#string

Kyungjae Myung

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Maria Jasin

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Nilabja Sikdar

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Soma Banerjee

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Stephen Wincovitch

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P2860

MDC1 is a mediator of the mammalian DNA damage checkpoint

BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates

hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks

Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination

Elg1 forms an alternative RFC complex important for DNA replication and genome integrity

ELG1, a yeast gene required for genome stability, forms a complex related to replication factor C

Saccharomyces cerevisiae CTF18 and CTF4 are required for sister chromatid cohesion

Elg1 forms an alternative PCNA-interacting RFC complex required to maintain genome stability.

A novel Rad24 checkpoint protein complex closely related to replication factor C.

The ELG1 clamp loader plays a role in sister chromatid cohesion

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10.4161/CC.8.19.9752

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19

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8

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26813677

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19755857

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