High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1
about
Human ABCA7 supports apolipoprotein-mediated release of cellular cholesterol and phospholipid to generate high density lipoproteinABCA5 resides in lysosomes, and ABCA5 knockout mice develop lysosomal disease-like symptomsDifferential phospholipid substrates and directional transport by ATP-binding cassette proteins ABCA1, ABCA7, and ABCA4 and disease-causing mutantsSynthetic LXR ligand inhibits the development of atherosclerosis in miceControl of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alphaGene therapy for lipid disordersInterstitial lung disease in children -- genetic background and associated phenotypes.ATP-binding cassette (ABC) transporters in normal and pathological lungMammalian P4-ATPases and ABC transporters and their role in phospholipid transportHigh-density Lipoproteins and Apolipoprotein A-I: Potential New Players in the Prevention and Treatment of Lung DiseaseBlack rice and anthocyanins induce inhibition of cholesterol absorption in vitroABCA1 overexpression leads to hyperalphalipoproteinemia and increased biliary cholesterol excretion in transgenic miceHepatobiliary cholesterol transport is not impaired in Abca1-null mice lacking HDLIs it time to modify the reverse cholesterol transport model?Monocyte/macrophage expression of ABCA1 has minimal contribution to plasma HDL levelsAbnormal lipoprotein metabolism and reversible female infertility in HDL receptor (SR-BI)-deficient miceNutritional lipidomics: molecular metabolism, analytics, and diagnosticsBeta-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatmentHelical apolipoproteins of high-density lipoprotein enhance phagocytosis by stabilizing ATP-binding cassette transporter A7The farnesoid X-receptor is an essential regulator of cholesterol homeostasisSterol regulatory element-binding protein-2- and liver X receptor-driven dual promoter regulation of hepatic ABC transporter A1 gene expression: mechanism underlying the unique response to cellular cholesterol statusIdentification and characterization of rodent ABCA1 in isolated type II pneumocytesInhibition of ERK1/2 and activation of liver X receptor synergistically induce macrophage ABCA1 expression and cholesterol effluxIdentification of three loci affecting HDL-cholesterol levels in a screen for chemically induced recessive mutations in micePreferential ATP-binding cassette transporter A1-mediated cholesterol efflux from late endosomes/lysosomesEffects of deletion of macrophage ABCA7 on lipid metabolism and the development of atherosclerosis in the presence and absence of ABCA1Epidemiology of age-related macular degeneration (AMD): associations with cardiovascular disease phenotypes and lipid factors."Skittish" Abca2 knockout mice display tremor, hyperactivity, and abnormal myelin ultrastructure in the central nervous system.Selective evaluation of high density lipoprotein from mouse small intestine by an in situ perfusion technique.Enlargement of high density lipoprotein in mice via liver X receptor activation requires apolipoprotein E and is abolished by cholesteryl ester transfer protein expression.Novel approaches to treating cardiovascular disease: lessons from Tangier disease.Transbilayer phospholipid movements in ABCA1-deficient cells.Prelesional arterial endothelial phenotypes in hypercholesterolemia: universal ABCA1 upregulation contrasts with region-specific gene expression in vivoVLDL/LDL acts as a drug carrier and regulates the transport and metabolism of drugs in the body.The effects of ABCG5/G8 polymorphisms on HDL-cholesterol concentrations depend on ABCA1 genetic variants in the Boston Puerto Rican Health StudyXenobiotic, bile acid, and cholesterol transporters: function and regulation.Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-IGenomewide Association Study Identifies Novel Genetic Loci That Modify Antiplatelet Effects and Pharmacokinetics of ClopidogrelThe ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout miceProject normal: defining normal variance in mouse gene expression.
P2860
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P2860
High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1
description
2000 nî lūn-bûn
@nan
2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
High density lipoprotein defic ...... binding cassette transporter-1
@ast
High density lipoprotein defic ...... binding cassette transporter-1
@en
type
label
High density lipoprotein defic ...... binding cassette transporter-1
@ast
High density lipoprotein defic ...... binding cassette transporter-1
@en
prefLabel
High density lipoprotein defic ...... binding cassette transporter-1
@ast
High density lipoprotein defic ...... binding cassette transporter-1
@en
P2093
P2860
P356
P1476
High density lipoprotein defic ...... binding cassette transporter-1
@en
P2093
C Aldinger
C Broccardo
P2860
P304
P356
10.1073/PNAS.97.8.4245
P407
P577
2000-04-01T00:00:00Z