Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes.
about
The Plasmodium berghei RC strain is highly diverged and harbors putatively novel drug resistance variants.Photosensitized INA-Labelled protein 1 (PhIL1) is novel component of the inner membrane complex and is required for Plasmodium parasite development.Profiling invasive Plasmodium falciparum merozoites using an integrated omics approach.Compositional and expression analyses of the glideosome during the Plasmodium life cycle reveal an additional myosin light chain required for maximum motility.The Promise of Systems Biology Approaches for Revealing Host Pathogen Interactions in Malaria.Genetically Validated Drug Targets in Leishmania; Current Knowledge and Future Prospects.A genetic screen in rodent malaria parasites identifies five new apicoplast putative membrane transporters, one of which is essential in human malaria parasites.The cytosolic glyoxalases of Plasmodium falciparum are dispensable during asexual blood-stage development.Identifying Potential Plasmodium vivax Sporozoite Stage Vaccine Candidates: An Analysis of Genetic Diversity and Natural Selection.The mitochondrial ribosomal protein L13 is critical for the structural and functional integrity of the mitochondrion in Plasmodium falciparum.Mutations in the pantothenate kinase of Plasmodium falciparum confer diverse sensitivity profiles to antiplasmodial pantothenate analogues.Phosphoethanolamine-N-methyltransferase is a potential biomarker for the diagnosis of P. knowlesi and P. falciparum malaria.Two essential Thioredoxins mediate apicoplast biogenesis, protein import, and gene expression in Toxoplasma gondii.Single-cell RNA-seq reveals hidden transcriptional variation in malaria parasitesDrugs in Development for Malaria.Inverse docking based screening and identification of protein targets for Cassiarin alkaloids against Plasmodium falciparum.Tackling resistance: emerging antimalarials and new parasite targets in the era of eliminationDeciphering the targets of retroviral protease inhibitors in Plasmodium bergheiRecQ helicases in the malaria parasite Plasmodium falciparum affect genome stability, gene expression patterns and DNA replication dynamicsEpistasis studies reveal redundancy among calcium-dependent protein kinases in motility and invasion of malaria parasitesUracil moieties in genomic DNAIntegrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasitesChallenges and recent progress in drug discovery for tropical diseasesSuppression of Drug Resistance Reveals a Genetic Mechanism of Metabolic Plasticity in Malaria ParasitesCharacterization of a Protein Phosphatase Type-1 and a Kinase Anchoring Protein in
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P2860
Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes.
description
2017 nî lūn-bûn
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2017 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2017 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
name
Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes.
@ast
Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes.
@en
type
label
Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes.
@ast
Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes.
@en
prefLabel
Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes.
@ast
Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes.
@en
P2093
P2860
P50
P1433
P1476
Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes.
@en
P2093
Akhil B Vaidya
Burcu Anar
Colin Herd
Ellen Bushell
Frank Schwach
Katarzyna Modrzynska
Oliver Billker
Rowena E Martin
Tom Metcalf
P2860
P304
260-272.e8
P356
10.1016/J.CELL.2017.06.030
P407
P50
P577
2017-07-01T00:00:00Z