Hypoxia modulates EWS-FLI1 transcriptional signature and enhances the malignant properties of Ewing's sarcoma cells in vitro.
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Bone Tumor Environment as a Potential Therapeutic Target in Ewing SarcomaMolecular mechanisms of ETS transcription factor-mediated tumorigenesisIntercohort gene expression co-analysis reveals chemokine receptors as prognostic indicators in Ewing's sarcomaHeterogeneous role of the glutathione antioxidant system in modulating the response of ESFT to fenretinide in normoxia and hypoxiaMetformin as an adjuvant drug against pediatric sarcomas: hypoxia limits therapeutic effects of the drugDual targeting of EWS-FLI1 activity and the associated DNA damage response with trabectedin and SN38 synergistically inhibits Ewing sarcoma cell growthMolecular dissection of the mechanism by which EWS/FLI expression compromises actin cytoskeletal integrity and cell adhesion in Ewing sarcoma.Signaling mechanisms of the epithelial-mesenchymal transition.Hypoxia, stem cells and bone tumorHypoxia-regulated target genes implicated in tumor metastasis.The association between let-7, RAS and HIF-1α in Ewing Sarcoma tumor growthThe CXCR4-CXCL12 axis in Ewing sarcoma: promotion of tumor growth rather than metastatic diseaseNeuropeptide Y (NPY) in tumor growth and progression: Lessons learned from pediatric oncologyHypoxia-inducible factor (HIF)-1α and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1α level and transcriptional activity.Systems biology of Ewing sarcoma: a network model of EWS-FLI1 effect on proliferation and apoptosis.Variability in functional p53 reactivation by PRIMA-1(Met)/APR-246 in Ewing sarcoma.Hypoxia shifts activity of neuropeptide Y in Ewing sarcoma from growth-inhibitory to growth-promoting effects.Biomarkers of Osteosarcoma, Chondrosarcoma, and Ewing Sarcoma.Oxidative stress and therapeutic opportunities: focus on the Ewing's sarcoma family of tumors.The tumor microenvironment: part 1.Drugs targeting the bone microenvironment: new therapeutic tools in Ewing's sarcoma?Hypoxia-inducible factors: mediators of cancer progression; prognostic and therapeutic targets in soft tissue sarcomas.Hsa-mir-145 is the top EWS-FLI1-repressed microRNA involved in a positive feedback loop in Ewing's sarcoma.TRAIL-based therapy in pediatric bone tumors: how to overcome resistance.Micro-Environmental Stress Induces Src-Dependent Activation of Invadopodia and Cell Migration in Ewing Sarcoma.In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis.Suppression of FOXO1 is responsible for a growth regulatory repressive transcriptional sub-signature of EWS-FLI1 in Ewing sarcoma.Factors Affecting EWS-FLI1 Activity in Ewing's Sarcoma.Cell-to-cell heterogeneity of EWSR1-FLI1 activity determines proliferation/migration choices in Ewing sarcoma cells.Bone sarcomas: from biology to targeted therapies.Next steps in preventing Ewing sarcoma progression.Established Models and New Paradigms for Hypoxia-Driven Cancer-Associated Bone Disease.Personalized genomic analysis based on circulating tumor cells of extra-skeletal Ewing sarcoma of the uterus: A case report of a 16-year-old Korean femaleMicroRNA‑34b promotes proliferation, migration and invasion of Ewing's sarcoma cells by downregulating Notch1
P2860
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P2860
Hypoxia modulates EWS-FLI1 transcriptional signature and enhances the malignant properties of Ewing's sarcoma cells in vitro.
description
2010 nî lūn-bûn
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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
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2010年學術文章
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name
Hypoxia modulates EWS-FLI1 tra ...... wing's sarcoma cells in vitro.
@ast
Hypoxia modulates EWS-FLI1 tra ...... wing's sarcoma cells in vitro.
@en
type
label
Hypoxia modulates EWS-FLI1 tra ...... wing's sarcoma cells in vitro.
@ast
Hypoxia modulates EWS-FLI1 tra ...... wing's sarcoma cells in vitro.
@en
prefLabel
Hypoxia modulates EWS-FLI1 tra ...... wing's sarcoma cells in vitro.
@ast
Hypoxia modulates EWS-FLI1 tra ...... wing's sarcoma cells in vitro.
@en
P2093
P2860
P1433
P1476
Hypoxia modulates EWS-FLI1 tra ...... wing's sarcoma cells in vitro.
@en
P2093
Dave N T Aryee
Idriss M Bennani-Baiti
Karin Muehlbacher
Maximilian Kauer
Michael Kreppel
Paul Meltzer
Raphaela Schwentner
Reinhard Kofler
Robert L Walker
P2860
P304
P356
10.1158/0008-5472.CAN-09-4333
P407
P577
2010-05-04T00:00:00Z