about
Translational toxicology and rescue strategies of the hERG channel dysfunction: biochemical and molecular mechanistic aspectsRole of risk stratification and genetics in sudden cardiac death.Molecular determinants of interactions between the N-terminal domain and the transmembrane core that modulate hERG K+ channel gating.Mutation and gender-specific risk in type 2 long QT syndrome: implications for risk stratification for life-threatening cardiac events in patients with long QT syndrome.Modification of hERG1 channel gating by Cd2+.Functional cross-talk between the α1- and β1-adrenergic receptors modulates the rapidly activating delayed rectifier potassium current in guinea pig ventricular myocytes.Isoform-specific dominant-negative effects associated with hERG1 G628S mutation in long QT syndrome.Nonsense-mediated mRNA decay caused by a frameshift mutation in a large kindred of type 2 long QT syndrome.Role of ion channels in sepsis-induced atrial tachyarrhythmias in guinea pigs.Interaction of local anesthetics with the K (+) channel pore domain: KcsA as a model for drug-dependent tetramer stabilityLQT2 nonsense mutations generate trafficking defective NH2-terminally truncated channels by the reinitiation of translation.HERG1 channel agonists and cardiac arrhythmia.Genomic biomarkers of SUDEP in brain and heart.Cardiac slices as a predictive tool for arrhythmogenic potential of drugs and chemicals.Cardiac electrophysiology in mice: a matter of size.Mechanism of electromechanical coupling in voltage-gated potassium channels.Predicting drug-induced QT prolongation and torsades de pointes: a review of preclinical endpoint measures.(-)-Epicatechin rescues the As2 O3 -induced HERG K(+) channel deficiency possibly through upregulating transcription factor SP1 expression.Fatty acid analogue N-arachidonoyl taurine restores function of IKs channels with diverse long QT mutations.Potassium Channels in Epilepsy.Beyond Anthracyclines: Preemptive Management of Cardiovascular Toxicity in the Era of Targeted Agents for Hematologic Malignancies.Molecular Pathophysiology of Congenital Long QT Syndrome.Acute and subacute effects of the selective serotonin-noradrenaline reuptake inhibitor duloxetine on cardiac hERG channels.Molecular Mechanisms of Crude Oil Developmental Toxicity in Fish.Placing ion channels into a signaling network of T cells: from maturing thymocytes to healthy T lymphocytes or leukemic T lymphoblasts.Early LQT2 nonsense mutation generates N-terminally truncated hERG channels with altered gating properties by the reinitiation of translation.Interactions between the N-terminal tail and the gating machinery of hERG K⁺ channels both in closed and open/inactive states.Blockade of permeation by potassium but normal gating of the G628S nonconducting hERG channel mutant.Gating mechanism of Kv11.1 (hERG) K+ channels without covalent connection between voltage sensor and pore domains.Postmortem genetic analysis of sudden unexpected death in infancy: neonatal genetic screening may enable the prevention of sudden infant death.Impact of novel N-aryl piperamide NO donors on NF-κB translocation in neuroinflammation: rational drug-designing synthesis and biological evaluation.Functional characterization of Kv11.1 (hERG) potassium channels split in the voltage-sensing domain.Relative positioning of Kv11.1 (hERG) K channel cytoplasmic domain-located fluorescent tags toward the plasma membrane
P2860
Q27008208-82E42F5C-56E6-4ED7-B6DE-48D0157E86F0Q30240811-EEACEF48-B9C3-4238-9618-19DAF574A9B1Q30474096-7E596AFF-8CFE-488A-919C-35A64AD05FF0Q33637446-4B767591-8EAD-4B9D-8A89-C9564E417C3DQ34028236-B3643E0E-804E-45F1-9989-8550FD2A5356Q34158573-012CE431-A063-4053-AC17-2548F4DDB333Q34372638-2AFC7384-2BC2-4149-A74D-9F1E7F7D4E74Q35180478-A5BF0EC3-F47E-4AE5-ADFB-14410642644FQ36153305-53511B21-DAC7-428E-9949-B660F253B97FQ37009060-703CB480-91F7-48BA-8ADF-027DF5C8E42EQ37342090-4C1752EA-632F-466D-A58C-874E5561EE55Q37699209-D46D036E-FDBC-4A42-87E5-8D8EAB0B8DB3Q37707209-00BB7A0D-4B45-41BB-9DDA-2DACF0184CB0Q37808482-E80CB01F-2B0D-40ED-A871-2831F6609483Q38042920-62D88DF6-8475-4788-8BCF-FEB33A1DFE28Q38044382-AFB0C1D4-CB88-4D56-93B6-81874EBA53C2Q38112652-BF1AA63B-E70D-4152-83A2-7A0ED54050EAQ38646540-5F8E15E7-FC20-458F-80B2-3E73302552CCQ38805694-2C4A7665-77B3-4125-BEC4-F2CF33F471E1Q38824328-D78E922D-C8A6-4F20-B4E1-8E751305AC37Q38944823-935C13AE-A43D-423A-AB90-871517BBF2D1Q38997049-301AC3AF-FE13-4E84-9D39-2BFC0532C636Q39153130-4B394120-FB44-4439-A636-C5B599EAE732Q39427481-0A71A36B-A1A2-46FD-9EC6-63F53225940AQ42061814-5EF0C9DA-E078-4F50-BD39-08D1F549C19DQ42177138-CE2D3137-ED19-47D9-86DB-85CB5A5E412EQ42683368-D8CB2F4C-534A-4330-988A-75483CFDBCDFQ42845231-7B626DB3-60B8-4301-929F-29774A37B673Q47261912-73D8C004-8B5D-4B1B-A23F-6C7033BC87D0Q47765779-307D63CA-A501-4968-BEA3-CFCDC2FD0DE2Q49959079-BA03567C-35D2-4129-AE68-F7EFAC88696CQ55385752-15A26AED-AD71-49BC-9881-F70E813C1A41Q57811395-820FB3FB-075D-495B-9D90-BD0A0784DF9F
P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
HERG1 channelopathies
@ast
HERG1 channelopathies
@en
type
label
HERG1 channelopathies
@ast
HERG1 channelopathies
@en
prefLabel
HERG1 channelopathies
@ast
HERG1 channelopathies
@en
P2860
P1433
P1476
HERG1 channelopathies
@en
P2093
Michael C Sanguinetti
P2860
P2888
P304
P356
10.1007/S00424-009-0758-8
P577
2009-11-22T00:00:00Z
P5875
P6179
1039057024