Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors.
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Interleukin-6 affects cell death escaping mechanisms acting on Bax-Ku70-Clusterin interactions in human colon cancer progressionp53 acetylation is crucial for its transcription-independent proapoptotic functionsNuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancerNon-homologous end joining, but not homologous recombination, enables survival for cells exposed to a histone deacetylase inhibitor.Protein post-translational modifications: In silico prediction tools and molecular modeling.Amphiregulin promotes resistance to gefitinib in nonsmall cell lung cancer cells by regulating Ku70 acetylation.Histone deacetylase inhibitor (HDACI) mechanisms of action: emerging insights.Regulation of ku70-bax complex in cells.Ku protein as the main cellular target of cell-surface-bound circulating DNA.The effects of histone deacetylase inhibitors on heterochromatin: implications for anticancer therapy?New insights into the link between DNA damage and apoptosis.SMAR1 coordinates HDAC6-induced deacetylation of Ku70 and dictates cell fate upon irradiation.CLU blocks HDACI-mediated killing of neuroblastoma.RuvBL2 is involved in histone deacetylase inhibitor PCI-24781-induced cell death in SK-N-DZ neuroblastoma cells.HDAC inhibitors potentiate the activity of the BCR/ABL kinase inhibitor KW-2449 in imatinib-sensitive or -resistant BCR/ABL+ leukemia cells in vitro and in vivo.Increased acetylation in the DNA-binding domain of TR4 nuclear receptor by the coregulator ARA55 leads to suppression of TR4 transactivationSuberoylanilide hydroxamic acid induces hypersensitivity to radiation therapy in acute myelogenous leukemia cells expressing constitutively active FLT3 mutants.Malignant T cells in cutaneous T-cell lymphoma lesions contain decreased levels of the antiapoptotic protein Ku70Histone deacetylase inhibitors sensitize lung cancer cells to hyperthermia: involvement of Ku70/SirT-1 in thermo-protectionHDAC6 deacetylates Ku70 and regulates Ku70-Bax binding in neuroblastoma.Bax deficiency extends the survival of Ku70 knockout mice that develop lung and heart diseases.Combined exercise and insulin-like growth factor-1 supplementation induces neurogenesis in old rats, but do not attenuate age-associated DNA damageDeformed epidermal autoregulatory factor-1 (DEAF1) interacts with the Ku70 subunit of the DNA-dependent protein kinase complex.CREB-binding protein is a mediator of neuroblastoma cell death induced by the histone deacetylase inhibitor trichostatin A.Interaction of a cyclin E fragment with Ku70 regulates Bax-mediated apoptosis.Endogenous modulators and pharmacological inhibitors of histone deacetylases in cancer therapy.Expression of the Ku70 subunit (XRCC6) and protection from low dose ionizing radiation during zebrafish embryogenesis.Prediction of Nepsilon-acetylation on internal lysines implemented in Bayesian Discriminant MethodResveratrol sensitizes acute myelogenous leukemia cells to histone deacetylase inhibitors through reactive oxygen species-mediated activation of the extrinsic apoptotic pathwaySubcellular Localization of Class I Histone Deacetylases in the Developing Xenopus tectum.Role of Ku70 and Bax in epigallocatechin-3-gallate-induced apoptosis of A549 cells in vivo.Regulation of the proapoptotic factor Bax by Ku70-dependent deubiquitylation.PLK1 inhibitors synergistically potentiate HDAC inhibitor lethality in imatinib mesylate-sensitive or -resistant BCR/ABL+ leukemia cells in vitro and in vivo.CREB-binding protein regulates Ku70 acetylation in response to ionization radiation in neuroblastomaComplex molecular mechanisms cooperate to mediate histone deacetylase inhibitors anti-tumour activity in neuroblastoma cells.A jekyll and hyde role of cyclin E in the genotoxic stress response: switching from cell cycle control to apoptosis regulation.The NAE inhibitor pevonedistat interacts with the HDAC inhibitor belinostat to target AML cells by disrupting the DDR.Epigenomics and breast cancerBax-induced apoptosis shortens the life span of DNA repair defect Ku70-knockout mice by inducing emphysema
P2860
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P2860
Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Ku70 acetylation mediates neur ...... istone deacetylase inhibitors.
@ast
Ku70 acetylation mediates neur ...... istone deacetylase inhibitors.
@en
type
label
Ku70 acetylation mediates neur ...... istone deacetylase inhibitors.
@ast
Ku70 acetylation mediates neur ...... istone deacetylase inhibitors.
@en
prefLabel
Ku70 acetylation mediates neur ...... istone deacetylase inhibitors.
@ast
Ku70 acetylation mediates neur ...... istone deacetylase inhibitors.
@en
P2093
P2860
P356
P1476
Ku70 acetylation mediates neur ...... istone deacetylase inhibitors.
@en
P2093
Anthony W Opipari
Chitra Subramanian
Roland P S Kwok
Valerie P Castle
P2860
P304
P356
10.1073/PNAS.0408351102
P407
P577
2005-03-18T00:00:00Z