Mechanism of specific membrane targeting by C2 domains: localized pools of target lipids enhance Ca2+ affinity.
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Dynamics and Membrane Interactions of Protein Kinase CBiophysical methods for the characterization of PTEN/lipid bilayer interactionsLateral diffusion of proteins on supported lipid bilayers: additive friction of synaptotagmin 7 C2A-C2B tandem domains.Structural determinants for Ca2+ and phosphatidylinositol 4,5-bisphosphate binding by the C2A domain of rabphilin-3AStructural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1Defining the interaction of perforin with calcium and the phospholipid membranePhospholipase A2 biochemistryPhospholipid-binding protein EhC2A mediates calcium-dependent translocation of transcription factor URE3-BP to the plasma membrane of Entamoeba histolytica.Ca2+ influx is an essential component of the positive-feedback loop that maintains leading-edge structure and activity in macrophages.Single-molecule studies reveal a hidden key step in the activation mechanism of membrane-bound protein kinase C-αActivation of L-type Ca2+ channels by protein kinase C is reduced in smooth muscle-specific Na+/Ca2+ exchanger knockout miceLocalization and function of cytosolic phospholipase A2alpha at the Golgi.Molecular mechanism of an oncogenic mutation that alters membrane targeting: Glu17Lys modifies the PIP lipid specificity of the AKT1 PH domain.Single molecule diffusion of membrane-bound proteins: window into lipid contacts and bilayer dynamics.An iron 13S-lipoxygenase with an α-linolenic acid specific hydroperoxidase activity from Fusarium oxysporum.Phosphatidylinositol 4,5-bisphosphate decreases the concentration of Ca2+, phosphatidylserine and diacylglycerol required for protein kinase C α to reach maximum activity.Phosphatidylinositol-4,5-bisphosphate enhances anionic lipid demixing by the C2 domain of PKCαDynamics of the phosphoinositide 3-kinase p110δ interaction with p85α and membranes reveals aspects of regulation distinct from p110αLipid targeting domain with dual-membrane specificity that expands the diversity of intracellular targeting reactions.Structural basis for calcium and phosphatidylserine regulation of phospholipase C δ1Membrane docking geometry and target lipid stoichiometry of membrane-bound PKCα C2 domain: a combined molecular dynamics and experimental study.The molecular basis of ceramide-1-phosphate recognition by C2 domains.Calcium-dependent isoforms of protein kinase C mediate glycine-induced synaptic enhancement at the calyx of Held.Regulation of PI3K by PKC and MARCKS: Single-Molecule Analysis of a Reconstituted Signaling PathwayRole of phosphorylation and basic residues in the catalytic domain of cytosolic phospholipase A2alpha in regulating interfacial kinetics and binding and cellular function.Single-molecule fluorescence studies of a PH domain: new insights into the membrane docking reaction.Phospholipases A2 and inflammatory responses in the central nervous system.Ferlin proteins in myoblast fusion and muscle growth.Interplay between phosphoinositide lipids and calcium signals at the leading edge of chemotaxing ameboid cells.Role of calcium in membrane interactions by PI(4,5)P₂-binding proteins.Hydrophobic contributions to the membrane docking of synaptotagmin 7 C2A domain: mechanistic contrast between isoforms 1 and 7The PIP2 binding mode of the C2 domains of rabphilin-3ANon-Native Metal Ion Reveals the Role of Electrostatics in Synaptotagmin 1-Membrane Interactions.Classical protein kinases C are regulated by concerted interaction with lipids: the importance of phosphatidylinositol-4,5-bisphosphate.Intramolecular conformational changes optimize protein kinase C signaling.Calcium binding rigidifies the C2 domain and the intradomain interaction of GIVA phospholipase A2 as revealed by hydrogen/deuterium exchange mass spectrometry.Calcium-dependent isoforms of protein kinase C mediate posttetanic potentiation at the calyx of Held.Effect of PIP2 binding on the membrane docking geometry of PKC alpha C2 domain: an EPR site-directed spin-labeling and relaxation studyC2 domain membrane penetration by group IVA cytosolic phospholipase A₂ induces membrane curvature changes.The TORC2-Dependent Signaling Network in the Yeast Saccharomyces cerevisiae.
P2860
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P2860
Mechanism of specific membrane targeting by C2 domains: localized pools of target lipids enhance Ca2+ affinity.
description
2007 nî lūn-bûn
@nan
2007 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մարտին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Mechanism of specific membrane ...... lipids enhance Ca2+ affinity.
@ast
Mechanism of specific membrane ...... lipids enhance Ca2+ affinity.
@en
type
label
Mechanism of specific membrane ...... lipids enhance Ca2+ affinity.
@ast
Mechanism of specific membrane ...... lipids enhance Ca2+ affinity.
@en
prefLabel
Mechanism of specific membrane ...... lipids enhance Ca2+ affinity.
@ast
Mechanism of specific membrane ...... lipids enhance Ca2+ affinity.
@en
P2093
P2860
P356
P1433
P1476
Mechanism of specific membrane ...... lipids enhance Ca2+ affinity.
@en
P2093
John A Corbin
John H Evans
Joseph J Falke
Kyle E Landgraf
P2860
P304
P356
10.1021/BI062140C
P407
P577
2007-03-17T00:00:00Z