The hepatitis C virus NS3 serine proteinase and NS4A cofactor: establishment of a cell-free trans-processing assay.
about
NS4A protein as a marker of HCV history suggests that different HCV genotypes originally evolved from genotype 1bInteractions between viral nonstructural proteins and host protein hVAP-33 mediate the formation of hepatitis C virus RNA replication complex on lipid raftDevelopment of a cell-based high-throughput specificity screen using a hepatitis C virus-bovine viral diarrhea virus dual replicon assay.Subcellular localization, stability, and trans-cleavage competence of the hepatitis C virus NS3-NS4A complex expressed in tetracycline-regulated cell lines.Stimulation of hepatitis C virus (HCV) nonstructural protein 3 (NS3) helicase activity by the NS3 protease domain and by HCV RNA-dependent RNA polymerasePreclinical profile of VX-950, a potent, selective, and orally bioavailable inhibitor of hepatitis C virus NS3-4A serine proteaseVX-950, a Novel Hepatitis C Virus (HCV) NS3-4A Protease Inhibitor, Exhibits Potent Antiviral Activities in HCV Replicon CellsTopology of the Membrane-Associated Hepatitis C Virus Protein NS4BEnzymatic characterization of hepatitis C virus NS3/4A complexes expressed in mammalian cells by using the herpes simplex virus amplicon systemChimeric Sindbis viruses dependent on the NS3 protease of hepatitis C virusThe NS3 proteinase domain of hepatitis C virus is a zinc-containing enzymePolynucleotide modulation of the protease, nucleoside triphosphatase, and helicase activities of a hepatitis C virus NS3-NS4A complex isolated from transfected COS cellsBovine viral diarrhea virus NS3 serine proteinase: polyprotein cleavage sites, cofactor requirements, and molecular model of an enzyme essential for pestivirus replicationProbing the substrate specificity of hepatitis C virus NS3 serine protease by using synthetic peptidesThe hepatitis C virus NS4A protein: interactions with the NS4B and NS5A proteinsA novel recombinant single-chain hepatitis C virus ns3-ns4a protein with improved helicase activityPhenotypic Characterization of Resistant Val36 Variants of Hepatitis C Virus NS3-4A Serine ProteasePhenotypic and structural analyses of hepatitis C virus NS3 protease Arg155 variants: sensitivity to telaprevir (VX-950) and interferon alphaThe herpesvirus proteases as targets for antiviral chemotherapy.Non-peptide inhibitors of HCV serine proteinase.Serpin mechanism of hepatitis C virus nonstructural 3 (NS3) protease inhibition: induced fit as a mechanism for narrow specificity.High-throughput screening of low molecular weight NS3-NS4A protease inhibitors using a fluorescence resonance energy transfer substrate.The NS3/4A proteinase of the hepatitis C virus: unravelling structure and function of an unusual enzyme and a prime target for antiviral therapy.Inhibitory effects of sudanese medicinal plant extracts on hepatitis C virus (HCV) protease.Antiviral activity of Acacia nilotica against Hepatitis C Virus in liver infected cellsAnalysis of the Enzymatic Activity of an NS3 Helicase Genotype 3a Variant Sequence Obtained from a Relapse Patient.Selectively infective phages (SIP).Real-world challenges for hepatitis C virus medications: a critical overview.Protease inhibitors as antiviral agents.In vitro resistance studies of hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061: structural analysis indicates different resistance mechanisms.Human and murine antibody recognition is focused on the ATPase/helicase, but not the protease domain of the hepatitis C virus nonstructural 3 protein.In vitro studies of cross-resistance mutations against two hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061.Hepatitis C virus NS4A and NS4B proteins suppress translation in vivo.Site-specific protease activity of the carboxyl-terminal domain of Semliki Forest virus replicase protein nsP2.Isolation and characterization of RNA aptamers specific for the hepatitis C virus nonstructural protein 3 protease.
P2860
Q21245104-1FC9E012-15C9-4AEE-9831-9067A7E44280Q24600344-769FA3C3-E2CF-4B6A-B34B-CCFAC0A3FAC8Q27469439-9732162C-63D4-4DFA-9053-74593CEA088DQ27469636-30D3946D-E4F5-4A7D-9F8C-49B4C1869FF2Q27470016-0FF04F80-9A2A-4773-9F59-A1EBAD177EB3Q27473126-0C597E87-2581-4BB3-BD21-163C6A02CFD1Q27473228-A8B4EB28-A853-4706-85CF-3DF52A6B4883Q27473470-2B113CBA-C3C7-48F1-91D1-5C60675535F6Q27480392-F210596A-0C9E-4C5B-B0D3-54BEBE931C2BQ27480780-5D5D0E63-C715-4BAB-8767-2B8A3875D83FQ27480807-EF94AE9D-1A69-4860-8E67-60A49B7917D3Q27480818-DE7AA5DD-27F6-4206-9582-67C0327F8879Q27480836-77C33591-F396-4F1F-A6AE-8D40E00D3E75Q27480843-4CC3043F-1BAF-4495-8C89-7F0A7F0355D2Q27480848-F7FE19CC-5410-44EE-8862-3764C87960A5Q27484233-804CC740-6A44-4516-B9C0-DDCF5990DDC3Q27485288-AAB3B751-66DE-45BD-B046-0C754F3E9AAAQ27645411-0CD54007-90BF-4C3B-8C0D-2146742F8FB2Q30842506-8D8C3904-EBC7-4C9A-91B1-8B21A8F06A1CQ32119135-8770D729-6F3D-4D75-B5A4-5DF78AA3869BQ33196330-8E969904-9905-43AE-99C8-554B7582CA20Q33228537-C0716DE8-DB90-4E93-B782-01BF6FF22816Q33801327-553E6FB2-EFDD-45B7-B5C5-C7E06A73FC08Q33923422-46422F0C-8AAE-40A3-8EE2-1269169DEEA7Q35047714-4EDA4CEF-D69D-48EB-8936-CFCCA7B36C2EQ35866961-966AC099-4B37-4C32-8153-580CB953E7FDQ36871226-D46A2784-57C7-497D-A36B-6193216F6A1FQ39326974-C84FB771-8089-43D0-9982-752F6C5162D4Q39468942-8FA18CCB-9940-4AC1-81E6-186462F6B79BQ42982898-539216B8-82B3-4975-8774-28D7FBD4F246Q42988935-C09FF688-CAB5-43AA-AAD4-7EF72F39429DQ42994273-C5809D01-9E31-49B8-BFC4-EA1BFE97563BQ43035975-43BCFD51-7293-4E51-B46E-B2123BFE6C7EQ43643522-D9B3A05C-876B-445E-8B91-2247D875C6C7Q45742035-2AC9FAAA-348F-4601-9514-8E146264FAFF
P2860
The hepatitis C virus NS3 serine proteinase and NS4A cofactor: establishment of a cell-free trans-processing assay.
description
1995 nî lūn-bûn
@nan
1995 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
The hepatitis C virus NS3 seri ...... l-free trans-processing assay.
@ast
The hepatitis C virus NS3 seri ...... l-free trans-processing assay.
@en
type
label
The hepatitis C virus NS3 seri ...... l-free trans-processing assay.
@ast
The hepatitis C virus NS3 seri ...... l-free trans-processing assay.
@en
prefLabel
The hepatitis C virus NS3 seri ...... l-free trans-processing assay.
@ast
The hepatitis C virus NS3 seri ...... l-free trans-processing assay.
@en
P2860
P356
P1476
The hepatitis C virus NS3 seri ...... l-free trans-processing assay.
@en
P2860
P304
P356
10.1073/PNAS.92.17.7622
P407
P577
1995-08-01T00:00:00Z