The beta subunit increases Ca2+ currents and gating charge movements of human cardiac L-type Ca2+ channels.
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Novel functional properties of Ca(2+) channel beta subunits revealed by their expression in adult rat heart cellsA short history of voltage-gated calcium channelsThe Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic PotentialGating deficiency in a familial hemiplegic migraine type 1 mutant P/Q-type calcium channelBARP suppresses voltage-gated calcium channel activity and Ca2+-evoked exocytosisExcitatory but not inhibitory synaptic transmission is reduced in lethargic (Cacnb4(lh)) and tottering (Cacna1atg) mouse thalamiThe ß subunit of voltage-gated Ca2+ channelsMembrane-associated guanylate kinase-like properties of beta-subunits required for modulation of voltage-dependent Ca2+ channelsBeta-subunits promote the expression of Ca(V)2.2 channels by reducing their proteasomal degradation.Multiple modulation pathways of calcium channel activity by a beta subunit. Direct evidence of beta subunit participation in membrane trafficking of the alpha1C subunit.Functional exofacially tagged N-type calcium channels elucidate the interaction with auxiliary α2δ-1 subunits.Recovery of Ca2+ current, charge movements, and Ca2+ transients in myotubes deficient in dihydropyridine receptor beta 1 subunit transfected with beta 1 cDNA.Reduced Ca2+ current, charge movement, and absence of Ca2+ transients in skeletal muscle deficient in dihydropyridine receptor beta 1 subunit.Differential regulation of skeletal muscle L-type Ca2+ current and excitation-contraction coupling by the dihydropyridine receptor beta subunit.Involvement of the carboxy-terminus region of the dihydropyridine receptor beta1a subunit in excitation-contraction coupling of skeletal muscleVariable ratio of permeability to gating charge of rBIIA sodium channels and sodium influx in Xenopus oocytes.Modulation of the gating of unitary cardiac L-type Ca(2+) channels by conditioning voltage and divalent ionsCalcium channel auxiliary α2δ and β subunits: trafficking and one step beyond.14-3-3τ promotes surface expression of Cav2.2 (α1B) Ca2+ channels.Regulation of maximal open probability is a separable function of Ca(v)beta subunit in L-type Ca2+ channel, dependent on NH2 terminus of alpha1C (Ca(v)1.2alpha).Ion-dependent inactivation of barium current through L-type calcium channels.Mechanism of auxiliary subunit modulation of neuronal alpha1E calcium channelsComplexes of the alpha1C and beta subunits generate the necessary signal for membrane targeting of class C L-type calcium channels.Autoimmune channelopathies as a novel mechanism in cardiac arrhythmias.Modified sympathetic nerve system activity with overexpression of the voltage-dependent calcium channel beta3 subunit.Molecular determinant for run-down of L-type Ca2+ channels localized in the carboxyl terminus of the 1C subunit.Role of the C terminus of the alpha 1C (CaV1.2) subunit in membrane targeting of cardiac L-type calcium channels.Current modulation and membrane targeting of the calcium channel alpha1C subunit are independent functions of the beta subunit.Differential effects of Ca2+ channel beta1a and beta2a subunits on complex formation with alpha1S and on current expression in tsA201 cells.Identification of palmitoylation sites within the L-type calcium channel beta2a subunit and effects on channel function.Molecular studies on the voltage dependence of dihydropyridine action on L-type Ca2+ channels. Critical involvement of tyrosine residues in motif IIIS6 and IVS6.The beta1a subunit regulates the functional properties of adult frog and mouse L-type Ca2+ channels of skeletal muscle.Membrane targeting of L-type calcium channels. Role of palmitoylation in the subcellular localization of the beta2a subunit.
P2860
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P2860
The beta subunit increases Ca2+ currents and gating charge movements of human cardiac L-type Ca2+ channels.
description
1996 nî lūn-bûn
@nan
1996 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի մարտին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
The beta subunit increases Ca2 ...... cardiac L-type Ca2+ channels.
@ast
The beta subunit increases Ca2 ...... cardiac L-type Ca2+ channels.
@en
The beta subunit increases Ca2 ...... cardiac L-type Ca2+ channels.
@nl
type
label
The beta subunit increases Ca2 ...... cardiac L-type Ca2+ channels.
@ast
The beta subunit increases Ca2 ...... cardiac L-type Ca2+ channels.
@en
The beta subunit increases Ca2 ...... cardiac L-type Ca2+ channels.
@nl
prefLabel
The beta subunit increases Ca2 ...... cardiac L-type Ca2+ channels.
@ast
The beta subunit increases Ca2 ...... cardiac L-type Ca2+ channels.
@en
The beta subunit increases Ca2 ...... cardiac L-type Ca2+ channels.
@nl
P2860
P1433
P1476
The beta subunit increases Ca2 ...... cardiac L-type Ca2+ channels.
@en
P2093
I R Josephson
P2860
P304
P356
10.1016/S0006-3495(96)79685-6
P407
P577
1996-03-01T00:00:00Z