Cellular senescence and the senescent secretory phenotype: therapeutic opportunities.
about
Multiple facets of p53 in senescence induction and maintenanceDNA Damage: A Main Determinant of Vascular Aging"Inflammaging" as a Druggable Target: A Senescence-Associated Secretory Phenotype-Centered View of Type 2 DiabetesFinding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging MoleculesMolecular mechanisms of biological aging in intervertebral discsCellular senescence impact on immune cell fate and functionCellular Senescence and the Biology of Aging, Disease, and FrailtyPathogenesis of endothelial cell dysfunction in chronic kidney disease: a retrospective and what the future may holdDNA damage response (DDR) and senescence: shuttled inflamma-miRNAs on the stage of inflamm-agingParainflammation, chronic inflammation, and age-related macular degenerationStromal Fibroblast in Age-Related Cancer: Role in Tumorigenesis and Potential as Novel Therapeutic TargetDo telomeres adapt to physiological stress? Exploring the effect of exercise on telomere length and telomere-related proteinsMacroautophagy and the oncogene-induced senescenceImmune surveillance of unhealthy cells by natural killer cellsPrimary biliary cirrhosis is a generalized autoimmune epithelitisTherapeutic targeting of replicative immortalityDynamic modelling of pathways to cellular senescence reveals strategies for targeted interventionsExtracellular microRNAs and endothelial hyperglycaemic memory: a therapeutic opportunity?Aging and adipose tissue: potential interventions for diabetes and regenerative medicineShort Telomeres in Key Tissues Initiate Local and Systemic Aging in ZebrafishPhosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cellsDefining the toxicology of agingRapamycin induces pluripotent genes associated with avoidance of replicative senescenceAging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cellsContact inhibition and high cell density deactivate the mammalian target of rapamycin pathway, thus suppressing the senescence programOxidative DNA damage caused by inflammation may link to stress-induced non-targeted effects.Loss of Arp2/3 induces an NF-κB-dependent, nonautonomous effect on chemotactic signalingAge-associated defects in EphA2 signaling impair the migration of human cardiac progenitor cells.Primary sclerosing cholangitis and the microbiota: current knowledge and perspectives on etiopathogenesis and emerging therapiesSenescence associated macrophages and "macroph-aging": are they pieces of the same puzzle?Developments in our understanding of the effects of growth hormone on white adipose tissue from mice: implications to the clinic.Identification of senescence-associated circular RNAs (SAC-RNAs) reveals senescence suppressor CircPVT1Old Maids: Aging and Its Impact on Microglia Function.Expansion of myeloid-derived suppressor cells with aging in the bone marrow of mice through a NF-κB-dependent mechanism.Ionizing radiation reduces ADAM10 expression in brain microvascular endothelial cells undergoing stress-induced senescence.Long-lived crowded-litter mice exhibit lasting effects on insulin sensitivity and energy homeostasis.Senescent tumor cells lead the collective invasion in thyroid cancer.Revisiting the hallmarks of cancer.Molecular and phenotypic biomarkers of agingp53 Modulates the Fate of Cardiac Progenitor Cells Ex Vivo and in the Diabetic Heart In Vivo.
P2860
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P2860
Cellular senescence and the senescent secretory phenotype: therapeutic opportunities.
description
2013 nî lūn-bûn
@nan
2013 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մարտին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Cellular senescence and the senescent secretory phenotype: therapeutic opportunities.
@ast
Cellular senescence and the senescent secretory phenotype: therapeutic opportunities.
@en
Cellular senescence and the senescent secretory phenotype: therapeutic opportunities.
@nl
type
label
Cellular senescence and the senescent secretory phenotype: therapeutic opportunities.
@ast
Cellular senescence and the senescent secretory phenotype: therapeutic opportunities.
@en
Cellular senescence and the senescent secretory phenotype: therapeutic opportunities.
@nl
prefLabel
Cellular senescence and the senescent secretory phenotype: therapeutic opportunities.
@ast
Cellular senescence and the senescent secretory phenotype: therapeutic opportunities.
@en
Cellular senescence and the senescent secretory phenotype: therapeutic opportunities.
@nl
P2093
P2860
P356
P1476
Cellular senescence and the senescent secretory phenotype: therapeutic opportunities.
@en
P2093
James L Kirkland
Jan van Deursen
Judith Campisi
Tamara Tchkonia
P2860
P304
P356
10.1172/JCI64098
P407
P577
2013-03-01T00:00:00Z