Synaptotagmin isoforms couple distinct ranges of Ca2+, Ba2+, and Sr2+ concentration to SNARE-mediated membrane fusion
about
Cell biology of Ca2+-triggered exocytosisSynaptotagmin-1 and -7 are functionally overlapping Ca2+ sensors for exocytosis in adrenal chromaffin cellsGenetic analysis of synaptotagmin-7 function in synaptic vesicle exocytosisThe functional significance of synaptotagmin diversity in neuroendocrine secretionSynaptotagmin-IV modulates synaptic function and long-term potentiation by regulating BDNF releaseSynaptotagmin 7 functions as a Ca2+-sensor for synaptic vesicle replenishmentAnalysis of the synaptotagmin family during reconstituted membrane fusion. Uncovering a class of inhibitory isoformsRelease mode of large and small dense-core vesicles specified by different synaptotagmin isoforms in PC12 cellsSynaptotagmin-mediated bending of the target membrane is a critical step in Ca(2+)-regulated fusionPalmitoylation-dependent association with CD63 targets the Ca2+ sensor synaptotagmin VII to lysosomesCa2+ and synaptotagmin VII-dependent delivery of lysosomal membrane to nascent phagosomes.Productive hemifusion intermediates in fast vesicle fusion driven by neuronal SNAREs.The mouth of a dense-core vesicle opens and closes in a concerted action regulated by calcium and amphiphysin.Axonal and dendritic synaptotagmin isoforms revealed by a pHluorin-syt functional screenCross-linking of phospholipid membranes is a conserved property of calcium-sensitive synaptotagminsLoss of synaptotagmin IV results in a reduction in synaptic vesicles and a distortion of the Golgi structure in cultured hippocampal neuronsMechanisms of neuromodulation as dissected using Sr2+ at motor nerve endingsDocking, not fusion, as the rate-limiting step in a SNARE-driven vesicle fusion assayRegulation of exocytosis and fusion pores by synaptotagmin-effector interactions.Linker mutations reveal the complexity of synaptotagmin 1 action during synaptic transmission.Distinct fusion properties of synaptotagmin-1 and synaptotagmin-7 bearing dense core granulesPhosphatidylserine in the brain: metabolism and function.Ca2+-triggered simultaneous membrane penetration of the tandem C2-domains of synaptotagmin IMechanism and function of synaptotagmin-mediated membrane apposition.Doc2 is a Ca2+ sensor required for asynchronous neurotransmitter release.Reconstituted synaptotagmin I mediates vesicle docking, priming, and fusion.Vesicle Motion during Sustained Exocytosis in Chromaffin Cells: Numerical Model Based on Amperometric Measurements.Structural elements that underlie Doc2β function during asynchronous synaptic transmission.An Engineered Metal Sensor Tunes the Kinetics of Synaptic Transmission.Synaptotagmin C2A loop 2 mediates Ca2+-dependent SNARE interactions essential for Ca2+-triggered vesicle exocytosisSex-specific regulation of follicle-stimulating hormone secretion by synaptotagmin 9.Regulation of insulin secretion and GLUT4 trafficking by the calcium sensor synaptotagmin VII.Expression and function of synaptotagmin VII in CTLsPurification, crystallization and X-ray diffraction analysis of human synaptotagmin 1 C2A-C2BCalcium-induced calcium release supports recruitment of synaptic vesicles in auditory hair cells.Different states of synaptotagmin regulate evoked versus spontaneous release.Network synchronization in hippocampal neuronsPutting the clamps on membrane fusion: how complexin sets the stage for calcium-mediated exocytosis.Doc2b promotes GLUT4 exocytosis by activating the SNARE-mediated fusion reaction in a calcium- and membrane bending-dependent mannerSynaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca2+.
P2860
Q26269905-EB338739-0F64-4489-83BB-82E862CD939DQ26269935-03FD2194-D76E-4A18-AFAE-0E7FD5BCD153Q26269936-E5A3AC57-D9AB-4EA7-A962-82148A219455Q26865014-5EF595F9-FBD7-40F4-B6FF-0AB1066DB81CQ28505296-29E31716-B870-4916-8A27-620C07104944Q28507653-FC19E15F-58D7-479F-9A29-D207B0DD0D87Q28576116-F6375F51-0B09-4E64-8C8E-E691D014766DQ28578017-9CE113E1-3178-42CE-9270-B25D064AA007Q28584744-9416A7A2-302D-4951-87FF-789610A4AF49Q28591116-F3A1EC7E-6FBD-42D7-8975-84B5B904E46AQ28594550-9EB2D440-3FCE-4322-BF07-B287692F99EDQ30481113-A42E71D8-A76A-4984-BDD0-C1201B6AD23CQ30483372-C141F0FB-E382-4EB6-8389-9C8DF80537A0Q30513861-2E1E6B20-20EB-4CBA-9E09-A59990E10B57Q33338314-D3E6A271-4BFB-4E48-845B-2871E9145976Q33529950-0A6B8DCA-C4A8-47FD-AF0C-D4CD040C65ECQ33699991-9920FBB2-A3A0-4371-AF9D-3B7F386DB14DQ33888728-4CAAA778-C877-43B9-91B8-C0B9AC290EB4Q34063787-428DFAE6-2963-4A33-BD6B-88A666532C33Q34069969-11E5A890-73BD-4C76-8285-2CAE8DEB78A4Q34081432-E2942CB2-917D-471F-B88B-C8ABCE0C5A73Q34647336-AF40C681-34B5-461C-AFA8-47432F241BE7Q34984621-78814751-9F88-4768-88F3-F021AD2E9893Q35089614-E7E41F21-5443-4D8D-AC5A-6447804F37F1Q35562324-B949A11E-01A6-4302-A611-539564953E72Q35636573-757A57D6-A354-45A9-A413-F153DD6E593EQ35870869-6B6037DE-1C87-4307-BF02-DA736E683D01Q35946201-44B5C150-659B-4ABB-A4C8-3794566C2544Q35995925-B9EF0CA6-0D68-4103-AED0-43FAB9A045E5Q36173880-905EC8B0-F232-46DA-AD34-4DF39B7595A7Q36207553-57ED4B78-4034-421F-96C7-B5E0F446C714Q36371942-40A04FED-EC2C-474E-B4B1-7278228F097CQ36388801-A75E1D47-EC4D-43D6-A61E-9D90DE35BC03Q36459421-0E49407A-FF67-4AF6-A488-D5544428E5A6Q36598054-146E0C59-6D58-4F92-BFA6-A4622190A1EBQ36719125-C95F7497-5DB9-4DF7-9DA6-256DCA14F4CAQ36742957-630B7854-9889-4F8B-A8A4-9505F5651099Q36756483-0F016642-74F1-471A-9356-4CC3B74ED832Q36758428-3C024307-A071-41D9-96CE-4120170EBA78Q36943507-CAB445E5-D7D3-4169-B132-4090DBCA778D
P2860
Synaptotagmin isoforms couple distinct ranges of Ca2+, Ba2+, and Sr2+ concentration to SNARE-mediated membrane fusion
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Synaptotagmin isoforms couple ...... SNARE-mediated membrane fusion
@ast
Synaptotagmin isoforms couple ...... SNARE-mediated membrane fusion
@en
Synaptotagmin isoforms couple ...... SNARE-mediated membrane fusion
@nl
type
label
Synaptotagmin isoforms couple ...... SNARE-mediated membrane fusion
@ast
Synaptotagmin isoforms couple ...... SNARE-mediated membrane fusion
@en
Synaptotagmin isoforms couple ...... SNARE-mediated membrane fusion
@nl
prefLabel
Synaptotagmin isoforms couple ...... SNARE-mediated membrane fusion
@ast
Synaptotagmin isoforms couple ...... SNARE-mediated membrane fusion
@en
Synaptotagmin isoforms couple ...... SNARE-mediated membrane fusion
@nl
P2860
P356
P1476
Synaptotagmin isoforms couple ...... SNARE-mediated membrane fusion
@en
P2093
Akhil Bhalla
Ward C Tucker
P2860
P304
P356
10.1091/MBC.E05-04-0277
P577
2005-08-10T00:00:00Z