Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in diabetic mice.
about
Development and characterization of a novel C-terminal inhibitor of Hsp90 in androgen dependent and independent prostate cancer cells.Baicalein alleviates diabetic peripheral neuropathy through inhibition of oxidative-nitrosative stress and p38 MAPK activation.Phenotypic changes in diabetic neuropathy induced by a high-fat diet in diabetic C57BL/6 mice.Heat shock response and insulin-associated neurodegeneration.C-terminal heat shock protein 90 inhibitor decreases hyperglycemia-induced oxidative stress and improves mitochondrial bioenergetics in sensory neurons.Modulating molecular chaperones improves sensory fiber recovery and mitochondrial function in diabetic peripheral neuropathyStandardized Profiling of The Membrane-Enriched Proteome of Mouse Dorsal Root Ganglia (DRG) Provides Novel Insights Into Chronic Pain.Modulating Molecular Chaperones Improves Mitochondrial Bioenergetics and Decreases the Inflammatory Transcriptome in Diabetic Sensory NeuronsSynthesis and evaluation of novologues as C-terminal Hsp90 inhibitors with cytoprotective activity against sensory neuron glucotoxicity.Diabetic peripheral neuropathy: should a chaperone accompany our therapeutic approach?KU-32, a novel drug for diabetic neuropathy, is safe for human islets and improves in vitro insulin secretion and viability.Induction of heat shock protein 70 (Hsp70) prevents neuregulin-induced demyelination by enhancing the proteasomal clearance of c-Jun.Development of Noviomimetics as C-Terminal Hsp90 InhibitorsEthoxyquin provides neuroprotection against cisplatin-induced neurotoxicityPromoting Neuronal Tolerance of Diabetic Stress: Modulating Molecular Chaperones.Heat shock protein 70 is necessary to improve mitochondrial bioenergetics and reverse diabetic sensory neuropathy following KU-32 therapy.Decreased thioredoxin-1 and increased HSP90 expression in skeletal muscle in subjects with type 2 diabetes or impaired glucose tolerance.Tolerating diabetes: an alternative therapeutic approach for diabetic neuropathy.Heat-shock protein 90 (Hsp90) promotes opioid-induced anti-nociception by an ERK mitogen-activated protein kinase (MAPK) mechanism in mouse brain.A Novel Class of Hsp90 C-Terminal Modulators Have Pre-Clinical Efficacy in Prostate Tumor Cells Without Induction of a Heat Shock Response.Drug-Induced HSP90 Inhibition Alleviates Pain in Monoarthritic Rats and Alters the Expression of New Putative Pain Players at the DRG.Targeting the Diabetic Chaperome to Improve Peripheral Neuropathy.Novel Molecular Strategies and Targets for Opioid Drug Discovery for the Treatment of Chronic Pain.Diverging Novobiocin Anti-Cancer Activity from Neuroprotective Activity through Modification of the Amide Tail.Role of Hypoxia Inducible Factor 1 in Hyperglycemia-Exacerbated Blood-Brain Barrier Disruption in Ischemic Stroke.Heat Shock Proteins in Vascular Diabetic Complications: Review and Future Perspective.Development of noviomimetics that modulate molecular chaperones and manifest neuroprotective effects.Targeting Heat Shock Protein 70 to Ameliorate c-Jun Expression and Improve Demyelinating Neuropathy.Modified biphenyl Hsp90 C-terminal inhibitors for the treatment of cancer.
P2860
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P2860
Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in diabetic mice.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in diabetic mice.
@ast
Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in diabetic mice.
@en
Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in diabetic mice.
@nl
type
label
Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in diabetic mice.
@ast
Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in diabetic mice.
@en
Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in diabetic mice.
@nl
prefLabel
Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in diabetic mice.
@ast
Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in diabetic mice.
@en
Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in diabetic mice.
@nl
P2093
P2860
P356
P1433
P1476
Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in diabetic mice.
@en
P2093
Brian S J Blagg
Chengyuan Li
Cuijuan Yu
Joanna M Krise
Michael J Urban
Michelle P McIntosh
Rick T Dobrowsky
Roger A Rajewski
Yuanming Lu
P2860
P304
P356
10.1042/AN20100015
P577
2010-08-11T00:00:00Z