Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells. - Wikidata - thesis-toulmin - TriplyDB

Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells.

Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells.

http://www.wikidata.org/entity/Q34069302

about

Therapeutic Implications of Targeting AKT Signaling in Melanoma Resistant mechanisms to BRAF inhibitors in melanoma Melanoma: oncogenic drivers and the immune system Emerging targeted therapies for melanoma treatment (review)Pathways and therapeutic targets in melanoma Resistance to BRAF inhibitors: unraveling mechanisms and future treatment options Reversing melanoma cross-resistance to BRAF and MEK inhibitors by co-targeting the AKT/mTOR pathway.Elucidating distinct roles for NF1 in melanomagenesis Alternative Treatments For Melanoma: Targeting BCL-2 Family Members to De-Bulk and Kill Cancer Stem Cells From bench to bedside: lessons learned in translating preclinical studies in cancer drug development AEBP1 upregulation confers acquired resistance to BRAF (V600E) inhibition in melanoma Function-Blocking ERBB3 Antibody Inhibits the Adaptive Response to RAF Inhibitor Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion Combinatorial drug screening and molecular profiling reveal diverse mechanisms of intrinsic and adaptive resistance to BRAF inhibition in V600E BRAF mutant melanomas.Effect of the leptin receptor Q223R polymorphism on the host transcriptome following infection with Entamoeba histolytica.Identification of glycogen synthase kinase 3α as a therapeutic target in melanoma Modulation of matrix elasticity with PEG hydrogels to study melanoma drug responsiveness.WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors.The MAPK pathway as an apoptosis enhancer in melanoma.The HSP90 inhibitor XL888 overcomes BRAF inhibitor resistance mediated through diverse mechanisms Targeted inhibition of BRAF kinase: opportunities and challenges for therapeutics in melanoma.Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis.Mouse hepatic oval cells require Met-dependent PI3K to impair TGF-β-induced oxidative stress and apoptosis.PTEN loss confers BRAF inhibitor resistance to melanoma cells through the suppression of BIM expression Sestrin2 protein positively regulates AKT enzyme signaling and survival in human squamous cell carcinoma and melanoma cells.Overcoming resistance to BRAF inhibition in BRAF-mutated metastatic melanoma BRAF inhibitor resistance mediated by the AKT pathway in an oncogenic BRAF mouse melanoma model Mechanisms of resistance to RAF inhibitors in melanoma Genomically amplified Akt3 activates DNA repair pathway and promotes glioma progression.Using quantitative proteomic analysis to understand genotype specific intrinsic drug resistance in melanoma.Adaptive upregulation of FOXD3 and resistance to PLX4032/4720-induced cell death in mutant B-RAF melanoma cells ERK2 phosphorylation of serine 77 regulates Bmf pro-apoptotic activity Replication-independent expression of anti-apoptosis marker genes in human peripheral blood mononuclear cells infected with the wild-type HIV-1 and reverse transcriptase variants NF-κB Regulation of c-FLIP Promotes TNFα-Mediated RAF Inhibitor Resistance in Melanoma The potential for BRAF V600 inhibitors in advanced cutaneous melanoma: rationale and latest evidence Therapeutic implications of targeting the PI3Kinase/AKT/mTOR signaling module in melanoma therapy.Targeting mutant BRAF in melanoma: current status and future development of combination therapy strategies Complexity in the signaling network: insights from the use of targeted inhibitors in cancer therapy.The Akt signaling pathway: an emerging therapeutic target in malignant melanoma.Effects of gender on gene expression in the blood of ischemic stroke patients.

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Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells.

http://www.wikidata.org/entity/Q34069302

description

2010 nî lūn-bûn

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2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

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name

Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells.

@ast

Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells.

@en

Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells.

@nl

type

label

Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells.

@ast

Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells.

@en

Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells.

@nl

prefLabel

Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells.

@ast

Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells.

@en

Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells.

@nl

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0008-5472.CAN-09-4471

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Cancer Research

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Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells.

@en

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Andrew E Aplin

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Yongping Shao

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P2860

Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis

VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

Disruption of epithelial cell-matrix interactions induces apoptosis

Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesis

A transforming mutation in the pleckstrin homology domain of AKT1 in cancer

Mutations of the BRAF gene in human cancer

Myofibroblasts and mechano-regulation of connective tissue remodelling

The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

Prostate epithelial cell lines form spheroids with evidence of glandular differentiation in three-dimensional Matrigel cultures

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6670-6681

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10.1158/0008-5472.CAN-09-4471

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16

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2010-07-20T00:00:00Z

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20647317

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