Anti-interleukin 6 receptor antibody treatment in rheumatic disease.
about
JAK/STAT but not ERK1/ERK2 pathway mediates interleukin (IL)-6/soluble IL-6R down-regulation of Type II collagen, aggrecan core, and link protein transcription in articular chondrocytes. Association with a down-regulation of SOX9 expressionJoint disease caused by defective gp130-mediated STAT signaling.Structure of the extracellular domains of the human interleukin-6 receptor alpha -chainThe pathological and physiological roles of IL-6 amplifier activationInverse correlation between serum interleukin-6 and iron levels among Japanese adults: a cross-sectional study.Directed evolution of a three-finger neurotoxin by using cDNA display yields antagonists as well as agonists of interleukin-6 receptor signaling.Autoimmune hepatitis: new paradigms in the pathogenesis, diagnosis, and management.Cytokine-modulating strategies and newer cytokine targets for arthritis therapy.Interleukin 6 in autoimmune and inflammatory diseases: a personal memoirIL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomised placebo-controlled trialThe adrenal hormone metabolism in the immune/inflammatory reaction.Etanercept ameliorates inflammation and pain in a novel mono-arthritic multi-flare model of streptococcal cell wall induced arthritis.Synovial macrophage-osteoclast differentiation in inflammatory arthritisSeeking balance: Potentiation and inhibition of multiple sclerosis autoimmune responses by IL-6 and IL-10.Cytokine signal regulation and autoimmune disorders.Radiation damage and radioprotectants: new concepts in the era of molecular medicineCytokine networks--towards new therapies for rheumatoid arthritis.Consensus statement on blocking the effects of interleukin-6 and in particular by interleukin-6 receptor inhibition in rheumatoid arthritis and other inflammatory conditions.Krüppel-Like Factor 4 Is a Regulator of Proinflammatory Signaling in Fibroblast-Like Synoviocytes through Increased IL-6 Expression.Methotrexate for the treatment of juvenile idiopathic arthritis: process to approval for JIA indication in Japan.Therapeutic efficacy of intra-articular adrenomedullin injection in antigen-induced arthritis in rabbits.Increased levels of IL-6, sIL-6R, and sgp130 in the aqueous humor and serum of patients with diabetic retinopathy.Serum interleukin-6 expression level and its clinical significance in patients with dermatomyositisBlockade of interleukin-6 signaling augments regulatory T-cell reconstitution and attenuates the severity of graft-versus-host disease.Long-term safety and efficacy of tocilizumab, an anti-IL-6 receptor monoclonal antibody, in monotherapy, in patients with rheumatoid arthritis (the STREAM study): evidence of safety and efficacy in a 5-year extension study.Tocilizumab: The evidence for its place in the treatment of juvenile idiopathic arthritis.Tocilizumab for the treatment of systemic juvenile idiopathic arthritis.Interleukin-6: possible biological roles during exercise.Tocilizumab for treating rheumatoid arthritis: an evaluation of pharmacokinetics/pharmacodynamics and clinical efficacy.Chemically modified DNA aptamers bind interleukin-6 with high affinity and inhibit signaling by blocking its interaction with interleukin-6 receptor.Old and new therapeutics for Rheumatoid Arthritis: in vivo models and drug development.Maternal serum amyloid A level as a novel marker of primary unexplained recurrent early pregnancy loss.Sarilumab and Nonbiologic Disease-Modifying Antirheumatic Drugs in Patients With Active Rheumatoid Arthritis and Inadequate Response or Intolerance to Tumor Necrosis Factor Inhibitors.Modulatory Effects of Chrysanyhemi Flos Pharmacopuncture on Nitric-oxide (NO) Production in Murin Macrophagy CellsTocilizumab in refractory adult Still's disease.Long-term efficacy and safety of tocilizumab in giant cell arteritis and large vessel vasculitisAutocrine insulin-like growth factor 1 and stem cell factor but not interleukin 6 support self-renewal of human myeloma cells.Cocoa flavonoid-enriched diet modulates systemic and intestinal immunoglobulin synthesis in adult Lewis rats.Increased levels of IL-6, IL-1β, and TNF-α in Kashin-Beck disease and rats induced by T-2 toxin and selenium deficiency.Profile of tocilizumab and its potential in the treatment of giant cell arteritis.
P2860
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P2860
Anti-interleukin 6 receptor antibody treatment in rheumatic disease.
description
2000 nî lūn-bûn
@nan
2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Anti-interleukin 6 receptor antibody treatment in rheumatic disease.
@ast
Anti-interleukin 6 receptor antibody treatment in rheumatic disease.
@en
Anti-interleukin 6 receptor antibody treatment in rheumatic disease.
@nl
type
label
Anti-interleukin 6 receptor antibody treatment in rheumatic disease.
@ast
Anti-interleukin 6 receptor antibody treatment in rheumatic disease.
@en
Anti-interleukin 6 receptor antibody treatment in rheumatic disease.
@nl
prefLabel
Anti-interleukin 6 receptor antibody treatment in rheumatic disease.
@ast
Anti-interleukin 6 receptor antibody treatment in rheumatic disease.
@en
Anti-interleukin 6 receptor antibody treatment in rheumatic disease.
@nl
P2093
P2860
P1476
Anti-interleukin 6 receptor antibody treatment in rheumatic disease.
@en
P2093
Kishimoto T
Nishimoto N
Yoshizaki K
P2860
P356
10.1136/ARD.59.SUPPL_1.I21
P407
P478
59 Suppl 1
P577
2000-11-01T00:00:00Z