Protein phosphatase 2A is a negative regulator of IL-2 production in patients with systemic lupus erythematosus.
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Dephosphorylation of Carma1 by PP2A negatively regulates T-cell activationDisturbed T Cell Signaling and Altered Th17 and Regulatory T Cell Subsets in the Pathogenesis of Systemic Lupus ErythematosusProtein Phosphatase Methyl-Esterase PME-1 Protects Protein Phosphatase 2A from Ubiquitin/Proteasome DegradationEndotoxin conditioning induces VCP/p97-mediated and inducible nitric-oxide synthase-dependent Tyr284 nitration in protein phosphatase 2A.The pathology of T cells in systemic lupus erythematosusTranscription factor Ikaros represses protein phosphatase 2A (PP2A) expression through an intronic binding site.Pathogenesis of human systemic lupus erythematosus: recent advances.The IL-2 defect in systemic lupus erythematosus disease has an expansive effect on host immunityT cells as therapeutic targets in SLE.Transcriptional activation of the cAMP-responsive modulator promoter in human T cells is regulated by protein phosphatase 2A-mediated dephosphorylation of SP-1 and reflects disease activity in patients with systemic lupus erythematosus.Spleen tyrosine kinase (Syk) regulates systemic lupus erythematosus (SLE) T cell signaling.Abnormalities of T cell signaling in systemic lupus erythematosus.Induction of PP2A Bβ, a regulator of IL-2 deprivation-induced T-cell apoptosis, is deficient in systemic lupus erythematosus.Promoter hypomethylation results in increased expression of protein phosphatase 2A in T cells from patients with systemic lupus erythematosus.Systemic lupus erythematosus: from genes to organ damage.Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups.T cells as a therapeutic target in SLE.The dysregulation of cytokine networks in systemic lupus erythematosus.Cutting edge: protein phosphatase 2A confers susceptibility to autoimmune disease through an IL-17-dependent mechanism.Estrogen upregulates cyclic AMP response element modulator α expression and downregulates interleukin-2 production by human T lymphocytesProtein kinase Cδ oxidation contributes to ERK inactivation in lupus T cellsSystems biology in systemic lupus erythematosus: integrating genes, biology and immune function.Guidelines for assessing immunocompetency in clinical trials for autoimmune diseases.Phosphatase PP2A is requisite for the function of regulatory T cells.Systemic lupus erythematosus: new molecular targets.The catalytic subunit of protein phosphatase 2A (PP2Ac) promotes DNA hypomethylation by suppressing the phosphorylated mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK)/phosphorylated ERK/DNMT1 protein pathwayNovel molecular targets in the treatment of systemic lupus erythematosus.PP2A dephosphorylates Elf-1 and determines the expression of CD3zeta and FcRgamma in human systemic lupus erythematosus T cells.Protein phosphatase 2A enables expression of interleukin 17 (IL-17) through chromatin remodelingTranscriptional regulation of IL-2 in health and autoimmunityEpigenetic mechanisms in lupus.Mechanisms for suppression of interleukin-6 expression in peritoneal macrophages from docosahexaenoic acid-fed miceA systemic lupus erythematosus gene expression array in disease diagnosis and classification: a preliminary report.Estradiol targets T cell signaling pathways in human systemic lupus.cAMP responsive element modulator: a critical regulator of cytokine productionBAFF activates Erk1/2 promoting cell proliferation and survival by Ca2+-CaMKII-dependent inhibition of PP2A in normal and neoplastic B-lymphoid cells.Role of Protein Phosphatase 2A in Osteoblast Differentiation and Function.Gene-function studies in systemic lupus erythematosus.Epigenetics in 2013. DNA methylation and miRNA: key roles in systemic autoimmunity.Interleukin 2 in the pathogenesis and therapy of type 1 diabetes.
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P2860
Protein phosphatase 2A is a negative regulator of IL-2 production in patients with systemic lupus erythematosus.
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Protein phosphatase 2A is a ne ...... systemic lupus erythematosus.
@ast
Protein phosphatase 2A is a ne ...... systemic lupus erythematosus.
@en
Protein phosphatase 2A is a ne ...... systemic lupus erythematosus.
@nl
type
label
Protein phosphatase 2A is a ne ...... systemic lupus erythematosus.
@ast
Protein phosphatase 2A is a ne ...... systemic lupus erythematosus.
@en
Protein phosphatase 2A is a ne ...... systemic lupus erythematosus.
@nl
prefLabel
Protein phosphatase 2A is a ne ...... systemic lupus erythematosus.
@ast
Protein phosphatase 2A is a ne ...... systemic lupus erythematosus.
@en
Protein phosphatase 2A is a ne ...... systemic lupus erythematosus.
@nl
P2093
P2860
P356
P1476
Protein phosphatase 2A is a ne ...... systemic lupus erythematosus.
@en
P2093
George C Tsokos
Vasileios C Kyttaris
Yuang-Taung Juang
P2860
P304
P356
10.1172/JCI24895
P407
P577
2005-10-13T00:00:00Z