A splice isoform of DNedd4, DNedd4-long, negatively regulates neuromuscular synaptogenesis and viability in Drosophila.
about
Drosophila Nedd4-long reduces Amphiphysin levels in muscles and leads to impaired T-tubule formation.Enhanced ubiquitin-dependent degradation by Nedd4 protects against α-synuclein accumulation and toxicity in animal models of Parkinson's disease.The role of ubiquitin-mediated pathways in regulating synaptic development, axonal degeneration and regeneration: insights from fly and worm.The WAGR syndrome gene PRRG4 is a functional homologue of the commissureless axon guidance gene.Septin 4, the drosophila ortholog of human CDCrel-1, accumulates in parkin mutant brains and is functionally related to the Nedd4 E3 ubiquitin ligase.
P2860
A splice isoform of DNedd4, DNedd4-long, negatively regulates neuromuscular synaptogenesis and viability in Drosophila.
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A splice isoform of DNedd4, DN ...... s and viability in Drosophila.
@ast
A splice isoform of DNedd4, DN ...... s and viability in Drosophila.
@en
A splice isoform of DNedd4, DN ...... s and viability in Drosophila.
@nl
type
label
A splice isoform of DNedd4, DN ...... s and viability in Drosophila.
@ast
A splice isoform of DNedd4, DN ...... s and viability in Drosophila.
@en
A splice isoform of DNedd4, DN ...... s and viability in Drosophila.
@nl
prefLabel
A splice isoform of DNedd4, DN ...... s and viability in Drosophila.
@ast
A splice isoform of DNedd4, DN ...... s and viability in Drosophila.
@en
A splice isoform of DNedd4, DN ...... s and viability in Drosophila.
@nl
P2093
P2860
P1433
P1476
A splice isoform of DNedd4, DN ...... s and viability in Drosophila.
@en
P2093
Alina Shtineman-Kotler
Daniela Rotin
Gabrielle L Boulianne
Konstantin G Iliadi
Leo Nguyen
P2860
P304
P356
10.1371/JOURNAL.PONE.0027007
P407
P50
P577
2011-11-14T00:00:00Z