Heterochromatin silencing of p53 target genes by a small viral protein.
about
Neuroblastoma: oncogenic mechanisms and therapeutic exploitation of necroptosisUncovering the role of p53 splice variants in human malignancy: a clinical perspectiveA Structural Basis for the Assembly and Functions of a Viral Polymer that Inactivates Multiple Tumor SuppressorsDrosophila Wnt and STAT Define Apoptosis-Resistant Epithelial Cells for Tissue Regeneration after Irradiationp53-mediated heterochromatin reorganization regulates its cell fate decisions.E1B and E4 oncoproteins of adenovirus antagonize the effect of apoptosis inducing factorProteasomal degradation of p53 by human papillomavirus E6 oncoprotein relies on the structural integrity of p53 core domain.Current status of gene therapy for brain tumors.Adenoviral vectors stimulate glucagon transcription in human mesenchymal stem cells expressing pancreatic transcription factors.The repression domain of the E1B 55-kilodalton protein participates in countering interferon-induced inhibition of adenovirus replication.P53-mediated rapid induction of apoptosis conveys resistance to viral infection in Drosophila melanogaster.Impact of the adenoviral E4 Orf3 protein on the activity and posttranslational modification of p53.Inhibition of p53 by adenovirus type 12 E1B-55K deregulates cell cycle control and sensitizes tumor cells to genotoxic agentsAdenovirus replaces mitotic checkpoint controls.Cytotoxic effects of replication-competent adenoviruses on human esophageal carcinoma are enhanced by forced p53 expression.Soluble guanylyl cyclase α1 and p53 cytoplasmic sequestration and down-regulation in prostate cancer.Discovery of Novel Isatin-Based p53 InducersTimely synthesis of the adenovirus type 5 E1B 55-kilodalton protein is required for efficient genome replication in normal human cells.Targeting Gene-Viro-Therapy with AFP driving Apoptin gene shows potent antitumor effect in hepatocarcinomaChanging the ubiquitin landscape during viral manipulation of the DNA damage response.A Multi Targeting Conditionally Replicating Adenovirus Displays Enhanced Oncolysis while Maintaining Expression of Immunotherapeutic Agents.Epigenetic mechanisms in virus-induced tumorigenesis.Genome-wide studies of the transcriptional regulation by p53.Functional and Structural Mimicry of Cellular Protein Kinase A Anchoring Proteins by a Viral OncoproteinCombination of a third generation bisphosphonate and replication-competent adenoviruses augments the cytotoxicity on mesothelioma.Biophysical and functional analyses suggest that adenovirus E4-ORF3 protein requires higher-order multimerization to function against promyelocytic leukemia protein nuclear bodiesAdenovirus E4-ORF3 Targets PIAS3 and Together with E1B-55K Remodels SUMO Interactions in the Nucleus and at Virus Genome Replication Domains.Human T-cell leukemia virus type 1 (HTLV-1) and leukemic transformation: viral infectivity, Tax, HBZ and therapy.Adenoviral protein V promotes a process of viral assembly through nucleophosmin 1.Visualizing viral protein structures in cells using genetic probes for correlated light and electron microscopy.The Adenovirus E4-ORF3 Protein Stimulates SUMOylation of General Transcription Factor TFII-I to Direct Proteasomal DegradationHuman cytomegalovirus pUL29/28 and pUL38 repression of p53-regulated p21CIP1 and caspase 1 promoters during infection.The p53 protein does not facilitate adenovirus type 5 replication in normal human cells.Long story short: p53 mediates innate immunity.Limited but durable changes to cellular gene expression in a model of latent adenovirus infection are reflected in childhood leukemic cell lines.Interference with p53 functions in human viral infections, a target for novel antiviral strategies?Extra sex combs, chromatin, and cancer: exploring epigenetic regulation and tumorigenesis in Drosophila.Design stars: how small DNA viruses remodel the host nucleus.Lysine-specific modifications of p53: a matter of life and death?Host-virus interactions: from the perspectives of epigenetics.
P2860
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P2860
Heterochromatin silencing of p53 target genes by a small viral protein.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Heterochromatin silencing of p53 target genes by a small viral protein.
@ast
Heterochromatin silencing of p53 target genes by a small viral protein.
@en
Heterochromatin silencing of p53 target genes by a small viral protein.
@nl
type
label
Heterochromatin silencing of p53 target genes by a small viral protein.
@ast
Heterochromatin silencing of p53 target genes by a small viral protein.
@en
Heterochromatin silencing of p53 target genes by a small viral protein.
@nl
prefLabel
Heterochromatin silencing of p53 target genes by a small viral protein.
@ast
Heterochromatin silencing of p53 target genes by a small viral protein.
@en
Heterochromatin silencing of p53 target genes by a small viral protein.
@nl
P2093
P2860
P356
P1433
P1476
Heterochromatin silencing of p53 target genes by a small viral protein.
@en
P2093
Clodagh C O'Shea
Conrado Soria
Fanny E Estermann
Kristen C Espantman
P2860
P2888
P304
P356
10.1038/NATURE09307
P407
P577
2010-08-01T00:00:00Z
P5875
P6179
1027064031