Gene expression signature in organized and growth-arrested mammary acini predicts good outcome in breast cancer
about
A comprehensive panel of three-dimensional models for studies of prostate cancer growth, invasion and drug responsesGrowth of lung cancer cells in three-dimensional microenvironments reveals key features of tumor malignancyDifferential gene expression in normal and transformed human mammary epithelial cells in response to oxidative stressUnraveling the microenvironmental influences on the normal mammary gland and breast cancerNetwork analysis of breast cancer progression and reversal using a tree-evolving network algorithmFrom microarray to biology: an integrated experimental, statistical and in silico analysis of how the extracellular matrix modulates the phenotype of cancer cells.Transcriptional Characterization of Compounds: Lessons Learned from the Public LINCS Data.Prognostic breast cancer signature identified from 3D culture model accurately predicts clinical outcome across independent datasetsA signature-based method for indexing cell cycle phase distribution from microarray profiles.Genomics Portals: integrative web-platform for mining genomics data.Vaccinia-related kinase 1 (VRK1) confers resistance to DNA-damaging agents in human breast cancer by affecting DNA damage responseMechanisms of disease: epithelial-mesenchymal transition--does cellular plasticity fuel neoplastic progression?Modelling molecular mechanisms of breast cancer and invasion: lessons from the normal glandCentrosomal protein 55 activates NF-κB signalling and promotes pancreatic cancer cells aggressiveness.Differential inhibitor sensitivity between human kinases VRK1 and VRK2.Extracellular matrix, nuclear and chromatin structure, and gene expression in normal tissues and malignant tumors: a work in progress.Gene expression in the third dimension: the ECM-nucleus connection.Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer.LMW-E/CDK2 deregulates acinar morphogenesis, induces tumorigenesis, and associates with the activated b-Raf-ERK1/2-mTOR pathway in breast cancer patientsGenome-wide gene expression analysis in cancer cells reveals 3D growth to affect ECM and processes associated with cell adhesion but not DNA repair.The need for complex 3D culture models to unravel novel pathways and identify accurate biomarkers in breast cancerIncreased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathwaysRaf-induced MMP9 disrupts tissue architecture of human breast cells in three-dimensional culture and is necessary for tumor growth in vivo.Primary trastuzumab resistance: new tricks for an old drug.Clinical relevance of Ephs and ephrins in cancer: lessons from breast, colorectal, and lung cancer profiling.The impact of adhesion peptides within hydrogels on the phenotype and signaling of normal and cancerous mammary epithelial cells.Design and Characterization of Novel EphA2 Agonists for Targeted Delivery of Chemotherapy to Cancer Cells.MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibitionThe Bag-1 inhibitor, Thio-2, reverses an atypical 3D morphology driven by Bag-1L overexpression in a MCF-10A model of ductal carcinoma in situ.Stromal genes add prognostic information to proliferation and histoclinical markers: a basis for the next generation of breast cancer gene signatures.Cell shape regulates global histone acetylation in human mammary epithelial cellsK-Ras and B-Raf oncogenes inhibit colon epithelial polarity establishment through up-regulation of c-myc.An "elite hacker": breast tumors exploit the normal microenvironment program to instruct their progression and biological diversity.The multifaceted roles of Eph/ephrin signaling in breast cancer.Locus-specific and activity-independent gene repositioning during early tumorigenesis.Molecular profiling of prostatic acinar morphogenesis identifies PDCD4 and KLF6 as tissue architecture-specific prognostic markers in prostate cancer.The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression.Regulation of tumor initiation and metastatic progression by Eph receptor tyrosine kinases.Three-dimensional cell culture to model epithelia in the female reproductive system.Molecular genetic analysis of VRK1 in mammary epithelial cells: depletion slows proliferation in vitro and tumor growth and metastasis in vivo.
P2860
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P2860
Gene expression signature in organized and growth-arrested mammary acini predicts good outcome in breast cancer
description
2006 nî lūn-bûn
@nan
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Gene expression signature in o ...... good outcome in breast cancer
@ast
Gene expression signature in o ...... good outcome in breast cancer
@en
Gene expression signature in o ...... good outcome in breast cancer
@nl
type
label
Gene expression signature in o ...... good outcome in breast cancer
@ast
Gene expression signature in o ...... good outcome in breast cancer
@en
Gene expression signature in o ...... good outcome in breast cancer
@nl
prefLabel
Gene expression signature in o ...... good outcome in breast cancer
@ast
Gene expression signature in o ...... good outcome in breast cancer
@en
Gene expression signature in o ...... good outcome in breast cancer
@nl
P2093
P2860
P1433
P1476
Gene expression signature in o ...... good outcome in breast cancer
@en
P2093
Irene Bosch
Katherine J Martin
Kris Xhaja
Marcia V Fournier
Mina J Bissell
Paraic A Kenny
Paul Yaswen
P2860
P304
P356
10.1158/0008-5472.CAN-06-0515
P407
P577
2006-07-01T00:00:00Z