Influenza A virus polymerase: structural insights into replication and host adaptation mechanisms
about
The polymerase of negative-stranded RNA virusesConnecting the study of wild influenza with the potential for pandemic diseaseThe Influenza Virus Polymerase Complex: An Update on Its Structure, Functions, and Significance for Antiviral Drug DesignUse of Aptamers as Diagnostics Tools and Antiviral Agents for Human VirusesMutational analysis of the binding pockets of the diketo acid inhibitor L-742,001 in the influenza virus PA endonucleaseAlteration of protein levels during influenza virus H1N1 infection in host cells: a proteomic survey of host and virus reveals differential dynamicsA penalized-likelihood method to estimate the distribution of selection coefficients from phylogenetic dataFunctional analysis of conserved motifs in influenza virus PB1 proteinProgress of small molecular inhibitors in the development of anti-influenza virus agents.Altered viral replication and cell responses by inserting microRNA recognition element into PB1 in pandemic influenza A virus (H1N1) 2009.Molecular analyses of H3N2 canine influenza viruses isolated from Korea during 2013-2014.A point mutation in the polymerase protein PB2 allows a reassortant H9N2 influenza isolate of wild-bird origin to replicate in human cellsMutations in polymerase genes enhanced the virulence of 2009 pandemic H1N1 influenza virus in miceCoESPRIT: a library-based construct screening method for identification and expression of soluble protein complexesGenomic and protein structural maps of adaptive evolution of human influenza A virus to increased virulence in the mouse.Viruses and prions of Saccharomyces cerevisiaeThematic minireview series: toward a structural basis for understanding influenza virus-host cell interactions.Generation and characterization of influenza A viruses with altered polymerase fidelity.Interactions between the influenza A virus RNA polymerase components and retinoic acid-inducible gene I.Influenza polymerase activity correlates with the strength of interaction between nucleoprotein and PB2 through the host-specific residue K/E627.Architecture and regulation of negative-strand viral enzymatic machineryHerpes Simplex Virus is Akt-ing in translational control.Integrating computational modeling and functional assays to decipher the structure-function relationship of influenza virus PB1 protein.Molecular basis of live-attenuated influenza virus.Interaction of the influenza A virus polymerase PB2 C-terminal region with importin alpha isoforms provides insights into host adaptation and polymerase assembly.Specific mutations in H5N1 mainly impact the magnitude and velocity of the host response in mice.A comprehensive map of the influenza A virus replication cycleCap-snatching mechanism in yeast L-A double-stranded RNA virusEquine and Canine Influenza H3N8 Viruses Show Minimal Biological Differences Despite Phylogenetic Divergence.Mechanisms of innate immune evasion in re-emerging RNA viruses.Temperature-Sensitive Mutants in the Influenza A Virus RNA Polymerase: Alterations in the PA Linker Reduce Nuclear Targeting of the PB1-PA Dimer and Result in Viral AttenuationIdentification of host genes linked with the survivability of chickens infected with recombinant viruses possessing H5N1 surface antigens from a highly pathogenic avian influenza virus.Ribosomal frameshifting used in influenza A virus expression occurs within the sequence UCC_UUU_CGU and is in the +1 direction.A novel small-molecule inhibitor of influenza A virus acts by suppressing PA endonuclease activity of the viral polymerase.Codon Deletions in the Influenza A Virus PA Gene Generate Temperature-Sensitive Viruses.New Insight into Metal Ion-Driven Catalysis of Nucleic Acids by Influenza PA-NterAntigenic drift of H1N1 influenza A virus in pigs with and without passive immunityN-acylhydrazone inhibitors of influenza virus PA endonuclease with versatile metal binding modes.Critical Role of the PA-X C-Terminal Domain of Influenza A Virus in Its Subcellular Localization and Shutoff ActivityVirology. Frameshifting to PA-X influenza
P2860
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P2860
Influenza A virus polymerase: structural insights into replication and host adaptation mechanisms
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Influenza A virus polymerase: ...... and host adaptation mechanisms
@ast
Influenza A virus polymerase: ...... and host adaptation mechanisms
@en
Influenza A virus polymerase: ...... and host adaptation mechanisms
@nl
type
label
Influenza A virus polymerase: ...... and host adaptation mechanisms
@ast
Influenza A virus polymerase: ...... and host adaptation mechanisms
@en
Influenza A virus polymerase: ...... and host adaptation mechanisms
@nl
prefLabel
Influenza A virus polymerase: ...... and host adaptation mechanisms
@ast
Influenza A virus polymerase: ...... and host adaptation mechanisms
@en
Influenza A virus polymerase: ...... and host adaptation mechanisms
@nl
P2860
P50
P356
P1476
Influenza A virus polymerase: ...... and host adaptation mechanisms
@en
P2093
Rob W H Ruigrok
P2860
P304
28411-28417
P356
10.1074/JBC.R110.117531
P407
P577
2010-06-10T00:00:00Z