Molecular rearrangements of the MLL gene are present in most cases of infant acute myeloid leukemia and are strongly correlated with monocytic or myelomonocytic phenotypes.
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Cdx4 and menin co-regulate Hoxa9 expression in hematopoietic cellsNew insight into the molecular mechanisms of MLL-associated leukemiaDietary flavonoids and the MLL gene: A pathway to infant leukemia?Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemiaStructure of the MLL CXXC domain-DNA complex and its functional role in MLL-AF9 leukemia.Crystal structure of menin reveals binding site for mixed lineage leukemia (MLL) proteinMenin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemiaMolecular basis of the mixed lineage leukemia-menin interaction: implications for targeting mixed lineage leukemias.The role of HTS in drug discovery at the University of Michigan.The role of therapeutic leukapheresis in hyperleukocytotic AML.Recent advances in the treatment of infant acute myeloid leukemia.MLL gene rearrangements in infant leukemia vary with age at diagnosis and selected demographic factors: a Children's Oncology Group (COG) study.Melanoma proteoglycan modifies gene expression to stimulate tumor cell motility, growth, and epithelial-to-mesenchymal transitionPseudo-rearrangement of the MLL gene at chromosome 11q23: a cautionary note on genotype analysis of leukaemia patients.Epigenetic regulations in hematopoietic Hox code.MLL-SEPT5 fusion transcript in infant acute myeloid leukemia with t(11;22)(q23;q11).Improved outcome of childhood acute myeloid leukemia in an Eastern European country: Lithuanian experience.Symptomatic central nervous system involvement in adult patients with acute myeloid leukemia.Establishment of a new human acute monocytic leukemia cell line TZ-1 with t(1;11)(p32;q23) and fusion gene MLL-EPS15.Successful Unrelated Stem Cell Transplantation in an Infant With Congenital Acute Myelogenous Leukemia FAB M5 Showing Massive Cutaneous Infiltrations--A Challenging Multidisciplinary Approach.Molecular analysis of infant acute leukemia.Flow cytometry: recent advances in diagnosis and monitoring of leukemia.Molecular targeting in acute myeloid leukemiaThe distribution of MLL breakpoints correlates with outcome in infant acute leukaemia.Siblings presenting with progressive congenital aleukemic leukemia cutis.Age-related patterns of immunoglobulin and T-cell receptor gene rearrangements in precursor-B-ALL: implications for detection of minimal residual disease.The MLL (11q23) and AF-4 (4q21) genes disrupted in t(4;11) acute leukemia: molecular and clinical studies.Acute myeloid leukemia with MLL rearrangements: clinicobiological features, prognostic impact and value of flow cytometry in the detection of residual leukemic cells.Facile target validation in an animal model with intracellularly expressed monobodiesAcute Myeloid Leukemia
P2860
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P2860
Molecular rearrangements of the MLL gene are present in most cases of infant acute myeloid leukemia and are strongly correlated with monocytic or myelomonocytic phenotypes.
description
1994 nî lūn-bûn
@nan
1994 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Molecular rearrangements of th ...... or myelomonocytic phenotypes.
@ast
Molecular rearrangements of th ...... or myelomonocytic phenotypes.
@en
Molecular rearrangements of th ...... or myelomonocytic phenotypes.
@nl
type
label
Molecular rearrangements of th ...... or myelomonocytic phenotypes.
@ast
Molecular rearrangements of th ...... or myelomonocytic phenotypes.
@en
Molecular rearrangements of th ...... or myelomonocytic phenotypes.
@nl
prefLabel
Molecular rearrangements of th ...... or myelomonocytic phenotypes.
@ast
Molecular rearrangements of th ...... or myelomonocytic phenotypes.
@en
Molecular rearrangements of th ...... or myelomonocytic phenotypes.
@nl
P2093
P2860
P356
P1476
Molecular rearrangements of th ...... or myelomonocytic phenotypes.
@en
P2093
D C Arthur
G D Hammond
I D Bernstein
J H Kersey
P H Sorensen
S J Korsmeyer
P2860
P304
P356
10.1172/JCI116978
P407
P577
1994-01-01T00:00:00Z