Slp4-a/granuphilin-a regulates dense-core vesicle exocytosis in PC12 cells.
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Munc18-1 regulates early and late stages of exocytosis via syntaxin-independent protein interactionsDistinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cellsRabphilin and Noc2 are recruited to dense-core vesicles through specific interaction with Rab27A in PC12 cellsThe C2B domain of rabphilin directly interacts with SNAP-25 and regulates the docking step of dense core vesicle exocytosis in PC12 cellsRNA interference-mediated silencing of synaptotagmin IX, but not synaptotagmin I, inhibits dense-core vesicle exocytosis in PC12 cellsSlac2-c (synaptotagmin-like protein homologue lacking C2 domains-c), a novel linker protein that interacts with Rab27, myosin Va/VIIa, and actinScrg1, a novel protein of the CNS is targeted to the large dense-core vesicles in neuronal cellsA general role for Rab27a in secretory cells.The interplay between the Rab27A effectors Slp4-a and MyRIP controls hormone-evoked Weibel-Palade body exocytosis.Regulation of synaptic transmission by RAB-3 and RAB-27 in Caenorhabditis elegans.Rab27A Is Present in Mouse Pancreatic Acinar Cells and Is Required for Digestive Enzyme Secretion.PI3K p110α/Akt signaling negatively regulates secretion of the intestinal peptide neurotensin through interference of granule transport.Atg16L1, an essential factor for canonical autophagy, participates in hormone secretion from PC12 cells independently of autophagic activity.Synaptotagmin-like proteins control the formation of a single apical membrane domain in epithelial cellsRab27A and its effector MyRIP link secretory granules to F-actin and control their motion towards release sitesHow peptide hormone vesicles are transported to the secretion site for exocytosis.Kinesin-1 controls mast cell degranulation and anaphylaxis through PI3K-dependent recruitment to the granular Slp3/Rab27b complex.Rab proteins and the secretory pathway: the case of rab18 in neuroendocrine cells.The actin-binding domain of Slac2-a/melanophilin is required for melanosome distribution in melanocytesStable RNA interference of synaptotagmin I in PC12 cells results in differential regulation of transmitter release.Roles of myosin Va and Rab3D in membrane remodeling of immature secretory granules.Downregulation of Rab27A contributes to metformin-induced suppression of breast cancer stem cellsThe Slp4-a linker domain controls exocytosis through interaction with Munc18-1.syntaxin-1a complex.Synaptotagmin-like protein 4 and Rab8 interact and increase dense granule release in platelets.Identification of Inherited Retinal Disease-Associated Genetic Variants in 11 Candidate Genes.Alternative splicing in the first alpha-helical region of the Rab-binding domain of Rim regulates Rab3A binding activity: is Rim a Rab3 effector protein during evolution?Nerve growth factor-dependent sorting of synaptotagmin IV protein to mature dense-core vesicles that undergo calcium-dependent exocytosis in PC12 cells.Slp4-a/granuphilin-a interacts with syntaxin-2/3 in a Munc18-2-dependent manner.Identification of Secretory Granule Phosphatidylinositol 4,5-Bisphosphate-interacting Proteins Using an Affinity Pulldown Strategy
P2860
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P2860
Slp4-a/granuphilin-a regulates dense-core vesicle exocytosis in PC12 cells.
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2002 nî lūn-bûn
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2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2002 թվականի օգոստոսին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年论文
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name
Slp4-a/granuphilin-a regulates dense-core vesicle exocytosis in PC12 cells.
@ast
Slp4-a/granuphilin-a regulates dense-core vesicle exocytosis in PC12 cells.
@en
Slp4-a/granuphilin-a regulates dense-core vesicle exocytosis in PC12 cells.
@nl
type
label
Slp4-a/granuphilin-a regulates dense-core vesicle exocytosis in PC12 cells.
@ast
Slp4-a/granuphilin-a regulates dense-core vesicle exocytosis in PC12 cells.
@en
Slp4-a/granuphilin-a regulates dense-core vesicle exocytosis in PC12 cells.
@nl
prefLabel
Slp4-a/granuphilin-a regulates dense-core vesicle exocytosis in PC12 cells.
@ast
Slp4-a/granuphilin-a regulates dense-core vesicle exocytosis in PC12 cells.
@en
Slp4-a/granuphilin-a regulates dense-core vesicle exocytosis in PC12 cells.
@nl
P2093
P2860
P356
P1476
Slp4-a/granuphilin-a regulates dense-core vesicle exocytosis in PC12 cells.
@en
P2093
Chika Saegusa
Eiko Kanno
Mitsunori Fukuda
Taruho S Kuroda
Yukie Ogata
P2860
P304
39673-39678
P356
10.1074/JBC.M205349200
P407
P577
2002-08-09T00:00:00Z