Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases. - Wikidata - thesis-toulmin - TriplyDB

Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases.

Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases.

http://www.wikidata.org/entity/Q34149948

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Neutrophil anti-neutrophil cytoplasmic autoantibody proteins: bactericidal increasing protein, lactoferrin, cathepsin, and elastase as serological markers of inflammatory bowel and other diseases Interleukin-1 Family Cytokines in Liver Diseases The Role of Serine Proteases and Antiproteases in the Cystic Fibrosis Lung New selective peptidyl di(chlorophenyl) phosphonate esters for visualizing and blocking neutrophil proteinase 3 in human diseases.Staphylococcus aureus secretes a unique class of neutrophil serine protease inhibitors Potent Elastase Inhibitors from Cyanobacteria: Structural Basis and Mechanisms Mediating Cytoprotective and Anti-Inflammatory Effects in Bronchial Epithelial Cells Structure basis 1/2SLPI and porcine pancreas trypsin interaction Potent and Selective Human Neutrophil Elastase Inhibitors with Novel Equatorial Ring Topology: in vivo Efficacy of the Polar Pyrimidopyridazine BAY-8040 in a Pulmonary Arterial Hypertension Rat Model Neutrophils: Between host defence, immune modulation, and tissue injury NSP4, an elastase-related protease in human neutrophils with arginine specificity Neutrophil serine proteases and their endogenous inhibitors in coronary artery ectasia patients N-Arylacyl O-sulfonated aminoglycosides as novel inhibitors of human neutrophil elastase, cathepsin G and proteinase 3 SerpinB1 is critical for neutrophil survival through cell-autonomous inhibition of cathepsin G Secretory leukocyte protease inhibitor (SLPI) is, like its homologue trappin-2 (pre-elafin), a transglutaminase substrate Transcriptome analysis of epigenetically modulated genome indicates signature genes in manifestation of type 1 diabetes and its prevention in NOD mice Overhauser-enhanced MRI of elastase activity from in vitro human neutrophil degranulation Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases Congenital neutropenia: diagnosis, molecular bases and patient management.Plant Proteinase Inhibitor BbCI Modulates Lung Inflammatory Responses and Mechanic and Remodeling Alterations Induced by Elastase in Mice.Protease Expression Levels in Prostate Cancer Tissue Can Explain Prostate Cancer-Associated Seminal Biomarkers-An Explorative Concept Study.Anti-allergic Hydroxy Fatty Acids from Typhonium blumei Explored through ChemGPS-NP.Alpha-1 antitrypsin, a diagnostic and prognostic marker of vernal keratoconjunctivitis.Large-scale proteomics differentiates cholesteatoma from surrounding tissues and identifies novel proteins related to the pathogenesis.Human cysteine cathepsins are not reliable markers of infection by Pseudomonas aeruginosa in cystic fibrosis.Functional characterization of polymorphisms in the peptidase inhibitor 3 (elafin) gene and validation of their contribution to risk of acute respiratory distress syndrome.Lack of cathelicidin processing in Papillon-Lefèvre syndrome patients reveals essential role of LL-37 in periodontal homeostasis Proteinase 3-dependent caspase-3 cleavage modulates neutrophil death and inflammation.Does human leukocyte elastase degrade intact skin elastin?Cytokines induced neutrophil extracellular traps formation: implication for the inflammatory disease condition.Bio-Revitalization: Effects of NASHA on Genes Involving Tissue Remodeling.PlGF mediates neutrophil elastase-induced airway epithelial cell apoptosis and emphysema The endogenous Th17 response in NO2-promoted allergic airway disease is dispensable for airway hyperresponsiveness and distinct from Th17 adoptive transfer.Sirtinol inhibits neutrophil elastase activity and attenuates lipopolysaccharide-mediated acute lung injury in mice Neutrophil serine proteases in antibacterial defense.FRET-based and other fluorescent proteinase probes.Design of ultrasensitive probes for human neutrophil elastase through hybrid combinatorial substrate library profiling.The serine protease inhibitor elafin maintains normal growth control by opposing the mitogenic effects of neutrophil elastase.Autoprocessing of neutrophil elastase near its active site reduces the efficiency of natural and synthetic elastase inhibitors.Proteinase 3 and Serpin B1: a novel pathway in the regulation of caspase-3 activation, neutrophil spontaneous apoptosis, and inflammation.Design of a Selective Substrate and Activity Based Probe for Human Neutrophil Serine Protease 4

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Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases.

http://www.wikidata.org/entity/Q34149948

description

2010 nî lūn-bûn

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2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Neutrophil elastase, proteinas ...... tic targets in human diseases.

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Neutrophil elastase, proteinas ...... tic targets in human diseases.

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Neutrophil elastase, proteinas ...... tic targets in human diseases.

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Neutrophil elastase, proteinas ...... tic targets in human diseases.

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Neutrophil elastase, proteinas ...... tic targets in human diseases.

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Neutrophil elastase, proteinas ...... tic targets in human diseases.

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Neutrophil elastase, proteinas ...... tic targets in human diseases.

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Neutrophil elastase, proteinas ...... tic targets in human diseases.

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Neutrophil elastase, proteinas ...... tic targets in human diseases.

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Pharmacological Reviews

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Neutrophil elastase, proteinas ...... tic targets in human diseases.

@en

P2093

Brice Korkmaz

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Dieter E Jenne

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Francis Gauthier

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Marshall S Horwitz

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P2860

Purifkation and Characterization of Elastase-Specific Inhibitor. Sequence Homology with Mucus Proteinase Inhibitor

Altered trafficking of lysosomal proteins in Hermansky-Pudlak syndrome due to mutations in the beta 3A subunit of the AP-3 adaptor

Cathepsin G activates protease-activated receptor-4 in human platelets

Structure of a serpin-protease complex shows inhibition by deformation

The granzyme B inhibitor, PI-9, is present in endothelial and mesothelial cells, suggesting that it protects bystander cells during immune responses

Killing activity of neutrophils is mediated through activation of proteases by K+ flux

Sequence and molecular characterization of human monocyte/neutrophil elastase inhibitor

Active site distortion is sufficient for proteinase inhibition by serpins: structure of the covalent complex of alpha1-proteinase inhibitor with porcine pancreatic elastase

Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2

Molecular cloning, expression, and partial characterization of two novel members of the ovalbumin family of serine proteinase inhibitors

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scholarly article

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10.1124/PR.110.002733

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4

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62

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2010-12-01T00:00:00Z

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21079042

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2993259

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