Aberrant cytoplasm localization and protein stability of SIRT1 is regulated by PI3K/IGF-1R signaling in human cancer cells. - Wikidata - thesis-toulmin - TriplyDB

Aberrant cytoplasm localization and protein stability of SIRT1 is regulated by PI3K/IGF-1R signaling in human cancer cells.

Aberrant cytoplasm localization and protein stability of SIRT1 is regulated by PI3K/IGF-1R signaling in human cancer cells.

http://www.wikidata.org/entity/Q34187339

about

Sirt1 and the Mitochondria The sirtuins promote Dishevelled-1 scaffolding of TIAM1, Rac activation and cell migration Perfluorooctanesulfonate Mediates Renal Tubular Cell Apoptosis through PPARgamma Inactivation Sirtuins: guardians of mammalian healthspan.Protein mislocalization: mechanisms, functions and clinical applications in cancer.Liver steatosis and increased ChREBP expression in mice carrying a liver specific SIRT1 null mutation under a normal feeding condition.SIRT1 deacetylase is overexpressed in human melanoma and its small molecule inhibition imparts anti-proliferative response via p53 activation The Expression of SIRT1 and DBC1 in Laryngeal and Hypopharyngeal Carcinomas.Ubiquitinated sirtuin 1 (SIRT1) function is modulated during DNA damage-induced cell death and survival.Induction of cell cycle arrest and apoptosis with downregulation of Hsp90 client proteins and histone modification by 4β-hydroxywithanolide E isolated from Physalis peruviana.Using mitochondrial sirtuins as drug targets: disease implications and available compounds.A small molecule Inauhzin inhibits SIRT1 activity and suppresses tumour growth through activation of p53.Mitochondrial transcription factor A serves as a danger signal by augmenting plasmacytoid dendritic cell responses to DNA.A biotin switch-based proteomics approach identifies 14-3-3ζ as a target of Sirt1 in the metabolic regulation of caspase-2.Janus-faced role of SIRT1 in tumorigenesis.SIRT1: Regulator of p53 Deacetylation Sirtuin 1 (SIRT1) and steroid hormone receptor activity in cancer Sirtuin deacetylases as therapeutic targets in the nervous system SIRT1 enhances matrix metalloproteinase-2 expression and tumor cell invasion in prostate cancer cells SIRT1 represses estrogen-signaling, ligand-independent ERα-mediated transcription, and cell proliferation in estrogen-responsive breast cells.The dual role of sirtuins in cancer.Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling.Sirtuin deacetylases in neurodegenerative diseases of aging.Sirtuins and cancer: new insights and cell signaling.SIRT1 regulation modulates stroke outcome.SIRT1 in neurodevelopment and brain senescence.Overexpression of Sirtuin-1 is associated with poor clinical outcome in esophageal squamous cell carcinoma.Sirtuin deacetylases: a new target for melanoma management.Clinicopathological significance of SIRT1 expression in colorectal adenocarcinoma.SIRT1 is upregulated in cutaneous T-cell lymphoma, and its inhibition induces growth arrest and apoptosis.DARPP-32 is required for MAPK/ERK signaling in thyroid cells.Inhibition of cortactin and SIRT1 expression attenuates migration and invasion of prostate cancer DU145 cells.Macromolecular crowding effect is critical for maintaining SIRT1's nuclear localization in cancer cells Nucleus or cytoplasm? The mysterious case of SIRT1's subcellular localization.The role of SIRT1 in cancer: the saga continues.Deacetylation of the tumor suppressor protein PML regulates hydrogen peroxide-induced cell death.Narrower insight to SIRT1 role in cancer: A potential therapeutic target to control epithelial-mesenchymal transition in cancer cells.Relation of the IGF/IGF1R system to autophagy in colitis and colorectal cancer.The dynamic shuttling of SIRT1 between cytoplasm and nuclei in bronchial epithelial cells by single and repeated cigarette smoke exposure.Expression/localization patterns of sirtuins (SIRT1, SIRT2, and SIRT7) during progression of cervical cancer and effects of sirtuin inhibitors on growth of cervical cancer cells.

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P2860

Aberrant cytoplasm localization and protein stability of SIRT1 is regulated by PI3K/IGF-1R signaling in human cancer cells.

http://www.wikidata.org/entity/Q34187339

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

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2010年論文

@zh-tw

2010年论文

@wuu

name

Aberrant cytoplasm localizatio ...... gnaling in human cancer cells.

@ast

Aberrant cytoplasm localizatio ...... gnaling in human cancer cells.

@en

Aberrant cytoplasm localizatio ...... gnaling in human cancer cells.

@nl

type

label

Aberrant cytoplasm localizatio ...... gnaling in human cancer cells.

@ast

Aberrant cytoplasm localizatio ...... gnaling in human cancer cells.

@en

Aberrant cytoplasm localizatio ...... gnaling in human cancer cells.

@nl

prefLabel

Aberrant cytoplasm localizatio ...... gnaling in human cancer cells.

@ast

Aberrant cytoplasm localizatio ...... gnaling in human cancer cells.

@en

Aberrant cytoplasm localizatio ...... gnaling in human cancer cells.

@nl

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International Journal of Biological Sciences

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Aberrant cytoplasm localizatio ...... ignaling in human cancer cells

@en

P2093

Douglas V Faller

http://www.w3.org/2001/XMLSchema#string

Joyce Wang

http://www.w3.org/2001/XMLSchema#string

Laura K Chmilewski

http://www.w3.org/2001/XMLSchema#string

Lijia Zhu

http://www.w3.org/2001/XMLSchema#string

Lora W Forman

http://www.w3.org/2001/XMLSchema#string

Vanessa Byles

http://www.w3.org/2001/XMLSchema#string

P2860

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation

Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses

The direct involvement of SirT1 in insulin-induced insulin receptor substrate-2 tyrosine phosphorylation

Role of SIRT1 in homologous recombination

Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence.

Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage

Sirtuin functions in health and disease

Sirtuin 1 is required for antagonist-induced transcriptional repression of androgen-responsive genes by the androgen receptor

Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins

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599-612

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10.7150/IJBS.6.599

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6

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6

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20941378

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2952410

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