Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair. - Wikidata - thesis-toulmin - TriplyDB

Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair.

Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair.

http://www.wikidata.org/entity/Q34218130

about

Chk1 phosphorylation of Metnase enhances DNA repair but inhibits replication fork restart APRIN is a cell cycle specific BRCA2-interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancer FBH1 promotes DNA double-strand breakage and apoptosis in response to DNA replication stress FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stress FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51 Single-molecule sorting reveals how ubiquitylation affects substrate recognition and activities of FBH1 helicase.Breast cancer proteins PALB2 and BRCA2 stimulate polymerase η in recombination-associated DNA synthesis at blocked replication forks A proteomic characterization of factors enriched at nascent DNA molecules 6-thioguanine selectively kills BRCA2-defective tumors and overcomes PARP inhibitor resistance DNA Damage Signalling and Repair Inhibitors: The Long-Sought-After Achilles' Heel of Cancer Managing Single-Stranded DNA during Replication Stress in Fission Yeast Replication Stress: A Lifetime of Epigenetic Change Rescuing stalled or damaged replication forks Mechanism and regulation of incisions during DNA interstrand cross-link repair Activation of new replication foci under conditions of replication stress.Disruption of SUMO-targeted ubiquitin ligases Slx5-Slx8/RNF4 alters RecQ-like helicase Sgs1/BLM localization in yeast and human cells.Replication stress: getting back on track Recovery from the DNA Replication Checkpoint Replication fork instability and the consequences of fork collisions from rereplication Replication stress in Mammalian cells and its consequences for mitosis A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination RAD51 mutants cause replication defects and chromosomal instability Polymerase δ replicates both strands after homologous recombination-dependent fork restart The cancer therapeutic potential of Chk1 inhibitors: how mechanistic studies impact on clinical trial design Initiation of genome instability and preneoplastic processes through loss of Fhit expression Interference in DNA replication can cause mitotic chromosomal breakage unassociated with double-strand breaks RECQL5 and BLM exhibit divergent functions in cells defective for the Fanconi anemia pathway The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype Chemical Inhibitors of Non-Homologous End Joining Increase Targeted Construct Integration in Cryptococcus neoformans Hot spots of DNA double-strand breaks and genomic contacts of human rDNA units are involved in epigenetic regulation Proteomic analysis of the response to cell cycle arrests in human myeloid leukemia cells USP7 is a SUMO deubiquitinase essential for DNA replication Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting Destabilized SMC5/6 complex leads to chromosome breakage syndrome with severe lung disease RecO protein initiates DNA recombination and strand annealing through two alternative DNA binding mechanisms.RTEL1 contributes to DNA replication and repair and telomere maintenance.Spontaneous slow replication fork progression elicits mitosis alterations in homologous recombination-deficient mammalian cells.Immortalised breast epithelia survive prolonged DNA replication stress and return to cycle from a senescent-like state.RFWD3-Dependent Ubiquitination of RPA Regulates Repair at Stalled Replication Forks.ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery.

P2860

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P2860

Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair.

http://www.wikidata.org/entity/Q34218130

description

2010 nî lūn-bûn

@nan

2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Hydroxyurea-stalled replicatio ...... thways for restart and repair.

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Hydroxyurea-stalled replicatio ...... thways for restart and repair.

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Hydroxyurea-stalled replicatio ...... thways for restart and repair.

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type

label

Hydroxyurea-stalled replicatio ...... thways for restart and repair.

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Hydroxyurea-stalled replicatio ...... thways for restart and repair.

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Hydroxyurea-stalled replicatio ...... thways for restart and repair.

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prefLabel

Hydroxyurea-stalled replicatio ...... thways for restart and repair.

@ast

Hydroxyurea-stalled replicatio ...... thways for restart and repair.

@en

Hydroxyurea-stalled replicatio ...... thways for restart and repair.

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J.MOLCEL.2010.01.021

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Hydroxyurea-stalled replicatio ...... athways for restart and repair

@en

P2093

Manuel Luís Orta

http://www.w3.org/2001/XMLSchema#string

Natalia Issaeva

http://www.w3.org/2001/XMLSchema#string

Niklas Schultz

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P2860

Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro

The BRC repeats of BRCA2 modulate the DNA-binding selectivity of RAD51

The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair

Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing

Homologous recombination in DNA repair and DNA damage tolerance

Replisome assembly and the direct restart of stalled replication forks

Characterization of homologous recombination induced by replication inhibition in mammalian cells

Pathways of DNA double-strand break repair during the mammalian cell cycle

Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage

The Bloom's syndrome helicase suppresses crossing over during homologous recombination

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492-502

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4

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37

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Thomas Helleday

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41621255

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20188668

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2958316

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