Huntingtin protein interactions altered by polyglutamine expansion as determined by quantitative proteomic analysis. - Wikidata - thesis-toulmin - TriplyDB

Huntingtin protein interactions altered by polyglutamine expansion as determined by quantitative proteomic analysis.

Huntingtin protein interactions altered by polyglutamine expansion as determined by quantitative proteomic analysis.

http://www.wikidata.org/entity/Q34274478

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Amyloid cannot resist identification Oligonucleotide-based strategies to combat polyglutamine diseases.Striatal Vulnerability in Huntington's Disease: Neuroprotection Versus Neurotoxicity.Proteins in aggregates functionally impact multiple neurodegenerative disease models by forming proteasome-blocking complexes.Phosphorylation of mutant huntingtin at serine 116 modulates neuronal toxicity.Bacterial expression and preliminary crystallographic studies of a 149-residue fragment of human Caprin-1.Proteins with Intrinsically Disordered Domains Are Preferentially Recruited to Polyglutamine Aggregates.Identification of novel polyglutamine-expanded aggregation species in spinal and bulbar muscular atrophy Mechanism of allele-selective inhibition of huntingtin expression by duplex RNAs that target CAG repeats: function through the RNAi pathway Protease-sensitive prions with 144-bp insertion mutations RNA toxicity in polyglutamine disorders: concepts, models, and progress of research Crystal structure of a dimerization domain of human Caprin-1: insights into the assembly of an evolutionarily conserved ribonucleoprotein complex consisting of Caprin-1, FMRP and G3BP1 Non-targeted identification of prions and amyloid-forming proteins from yeast and mammalian cells.New insight into neurodegeneration: the role of proteomics.Challenges of Huntington's disease and quest for therapeutic biomarkers.Invited review: decoding the pathophysiological mechanisms that underlie RNA dysregulation in neurodegenerative disorders: a review of the current state of the art.Allele-selective suppression of mutant genes in polyglutamine diseases.RNA processing-associated molecular mechanisms of neurodegenerative diseases.Exosomes and Homeostatic Synaptic Plasticity Are Linked to Each other and to Huntington's, Parkinson's, and Other Neurodegenerative Diseases by Database-Enabled Analyses of Comprehensively Curated Datasets.Epigenetic mechanisms in neurogenesis.RNA toxicity induced by expanded CAG repeats in Huntington's disease.A link between chromatin condensation mechanisms and Huntington's disease: connecting the dots.Huntington's Disease: Mechanisms of Pathogenesis and Therapeutic Strategies.Huntingtin polyQ Mutation Impairs the 17β-Estradiol/Neuroglobin Pathway Devoted to Neuron Survival.Neuroglobin and friends.Transcriptome sequencing reveals aberrant alternative splicing in Huntington's disease.Quantitative Proteomic Analysis Reveals Similarities between Huntington's Disease (HD) and Huntington's Disease-Like 2 (HDL2) Human Brains.PRMT5- mediated symmetric arginine dimethylation is attenuated by mutant huntingtin and is impaired in Huntington's disease (HD).Post-translational modifications clustering within proteolytic domains decrease mutant huntingtin toxicity.Aberrant subcellular localization of SQSTM1/p62 contributes to increased vulnerability to proteotoxic stress recovery in Huntington's disease.A comprehensive in silico analysis of huntingtin and its interactome.Maintenance of the Innate Seizure Threshold by Cyclooxygenase-2 is Not Influenced by the Translational Silencer, T-cell Intracellular Antigen-1.Profilin reduces aggregation and phase separation of huntingtin N-terminal fragments by preferentially binding to soluble monomers and oligomers.The COOH-terminal domain of huntingtin interacts with RhoGEF kalirin and modulates cell survival.RNAi-based therapies for Huntington’s disease: delivery challenges and opportunities Protein Co-Aggregation Related to Amyloids: Methods of Investigation, Diversity, and Classification Crosstalk between Endoplasmic Reticulum Stress and Protein Misfolding in Neurodegenerative Diseases

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Huntingtin protein interactions altered by polyglutamine expansion as determined by quantitative proteomic analysis.

http://www.wikidata.org/entity/Q34274478

description

2012 nî lūn-bûn

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2012 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2012 թվականի մայիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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Huntingtin protein interaction ...... antitative proteomic analysis.

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Huntingtin protein interaction ...... antitative proteomic analysis.

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Huntingtin protein interaction ...... antitative proteomic analysis.

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Huntingtin protein interaction ...... antitative proteomic analysis.

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Huntingtin protein interaction ...... antitative proteomic analysis.

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Huntingtin protein interaction ...... antitative proteomic analysis.

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Huntingtin protein interaction ...... antitative proteomic analysis.

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Huntingtin protein interaction ...... antitative proteomic analysis.

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Huntingtin protein interaction ...... uantitative proteomic analysis

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Ekaterine Chighladze

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Nicolas Arbez

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Robert N Cole

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Tamara Ratovitski

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Tatiana Boronina

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P2860

Huntingtin interacting proteins are genetic modifiers of neurodegeneration

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

A brain-specific isoform of mitochondrial apoptosis-inducing factor: AIF2

Export of mitochondrial AIF in response to proapoptotic stimuli depends on processing at the intermembrane space

A huntingtin-associated protein enriched in brain with implications for pathology

A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease

Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme

Rhes, a striatal specific protein, mediates mutant-huntingtin cytotoxicity

HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain

HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system

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2006-2021

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scholarly article

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10.4161/CC.20423

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10

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11

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Shelley M Herbrich

Christopher A Ross

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2012-05-15T00:00:00Z

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224949713

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3359124

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