Probing molecular mechanisms of the Hsp90 chaperone: biophysical modeling identifies key regulators of functional dynamics.
about
Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewThe impact of a ligand binding on strand migration in the SAM-I riboswitchDifferential modulation of functional dynamics and allosteric interactions in the Hsp90-cochaperone complexes with p23 and Aha1: a computational study.Allosteric regulation of the Hsp90 dynamics and stability by client recruiter cochaperones: protein structure network modelingComputational modeling of allosteric regulation in the hsp90 chaperones: a statistical ensemble analysis of protein structure networks and allosteric communications.Structure-based network analysis of activation mechanisms in the ErbB family of receptor tyrosine kinases: the regulatory spine residues are global mediators of structural stability and allosteric interactions.Dancing through Life: Molecular Dynamics Simulations and Network-Centric Modeling of Allosteric Mechanisms in Hsp70 and Hsp110 Chaperone Proteins.Computational Analysis of Residue Interaction Networks and Coevolutionary Relationships in the Hsp70 Chaperones: A Community-Hopping Model of Allosteric Regulation and CommunicationLong noncoding RNA CPS1-IT1 suppresses the metastasis of hepatocellular carcinoma by regulating HIF-1α activity and inhibiting epithelial-mesenchymal transition.Molecular dynamics simulations of hsp90 with an eye to inhibitor design.Heat-shock protein 90 (Hsp90) as anticancer target for drug discovery: an ample computational perspective.Mechanism of Inhibition of Hsp90 Dimerization by Gyrase B Inhibitor Coumermycin A1 (C-A1) Revealed by Molecular Dynamics Simulations and Thermodynamic Calculations.Force distribution reveals signal transduction in E. coli Hsp90.Structural bioinformatics and protein docking analysis of the molecular chaperone-kinase interactions: towards allosteric inhibition of protein kinases by targeting the hsp90-cdc37 chaperone machinery.Atomistic simulations and network-based modeling of the Hsp90-Cdc37 chaperone binding with Cdk4 client protein: A mechanism of chaperoning kinase clients by exploiting weak spots of intrinsically dynamic kinase domains.Computational close up on protein-protein interactions: how to unravel the invisible using molecular dynamics simulations?Evolution of In Silico Strategies for Protein-Protein Interaction Drug Discovery
P2860
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P2860
Probing molecular mechanisms of the Hsp90 chaperone: biophysical modeling identifies key regulators of functional dynamics.
description
2012 nî lūn-bûn
@nan
2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Probing molecular mechanisms o ...... lators of functional dynamics.
@ast
Probing molecular mechanisms o ...... lators of functional dynamics.
@en
Probing molecular mechanisms o ...... lators of functional dynamics.
@nl
type
label
Probing molecular mechanisms o ...... lators of functional dynamics.
@ast
Probing molecular mechanisms o ...... lators of functional dynamics.
@en
Probing molecular mechanisms o ...... lators of functional dynamics.
@nl
prefLabel
Probing molecular mechanisms o ...... lators of functional dynamics.
@ast
Probing molecular mechanisms o ...... lators of functional dynamics.
@en
Probing molecular mechanisms o ...... lators of functional dynamics.
@nl
P2860
P1433
P1476
Probing molecular mechanisms o ...... lators of functional dynamics.
@en
P2093
Anshuman Dixit
P2860
P304
P356
10.1371/JOURNAL.PONE.0037605
P407
P577
2012-05-18T00:00:00Z