AMP-activated protein kinase (AMPK) negatively regulates Nox4-dependent activation of p53 and epithelial cell apoptosis in diabetes. - Wikidata - thesis-toulmin - TriplyDB

AMP-activated protein kinase (AMPK) negatively regulates Nox4-dependent activation of p53 and epithelial cell apoptosis in diabetes.

AMP-activated protein kinase (AMPK) negatively regulates Nox4-dependent activation of p53 and epithelial cell apoptosis in diabetes.

http://www.wikidata.org/entity/Q34333672

about

Role of autophagy in chronic kidney diseases Role of redoximiRs in fibrogenesis The balance of powers: Redox regulation of fibrogenic pathways in kidney injury Molecular mechanisms of diabetic kidney disease Role of NADPH Oxidase in Metabolic Disease-Related Renal Injury: An Update Obesity and Diabetic Kidney Disease: Role of Oxidant Stress and Redox Balance Mitochondrial hormesis and diabetic complications c-Abl mediates angiotensin II-induced apoptosis in podocytes Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes Wild-type and mutant p53 differentially regulate NADPH oxidase 4 in TGF-β-mediated migration of human lung and breast epithelial cells Fatty Acid Oxidation Compensates for Lipopolysaccharide-Induced Warburg Effect in Glucose-Deprived Monocytes.Nox4 mediates renal cell carcinoma cell invasion through hypoxia-induced interleukin 6- and 8- production.Sestrins orchestrate cellular metabolism to attenuate aging.New targets for treatment of diabetic nephropathy: what we have learned from animal models.20-HETE and EETs in diabetic nephropathy: a novel mechanistic pathway MicroRNA-21 orchestrates high glucose-induced signals to TOR complex 1, resulting in renal cell pathology in diabetes.New insight into the molecular drug target of diabetic nephropathy.Antioxidant and anti-inflammatory activities of berberine in the treatment of diabetes mellitus.Insulin signaling: implications for podocyte biology in diabetic kidney disease.Upstream regulators and downstream effectors of NADPH oxidases as novel therapeutic targets for diabetic kidney disease.Tadalafil Integrates Nitric Oxide-Hydrogen Sulfide Signaling to Inhibit High Glucose-induced Matrix Protein Synthesis in Podocytes p47(phox) contributes to albuminuria and kidney fibrosis in mice.AMP-activated protein kinase (AMPK) activation inhibits nuclear translocation of Smad4 in mesangial cells and diabetic kidneys.Targeting NADPH oxidase with a novel dual Nox1/Nox4 inhibitor attenuates renal pathology in type 1 diabetes.Hydrogen sulfide inhibits high glucose-induced matrix protein synthesis by activating AMP-activated protein kinase in renal epithelial cells.IGF-I increases the expression of fibronectin by Nox4-dependent Akt phosphorylation in renal tubular epithelial cells Conditioned Medium from Early-Outgrowth Bone Marrow Cells Is Retinal Protective in Experimental Model of Diabetes Regulation of NAD(P)H oxidases by AMPK in cardiovascular systems Activation of AMP-activated protein kinase prevents TGF-β1-induced epithelial-mesenchymal transition and myofibroblast activation.Role of apoptosis-inducing factor, proline dehydrogenase, and NADPH oxidase in apoptosis and oxidative stress Reversal of persistent fibrosis in aging by targeting Nox4-Nrf2 redox imbalance The impact of thiamine treatment in the diabetes mellitus.A novel inverse relationship between metformin-triggered AMPK-SIRT1 signaling and p53 protein abundance in high glucose-exposed HepG2 cells.Transforming Growth Factor β1-induced Apoptosis in Podocytes via the Extracellular Signal-regulated Kinase-Mammalian Target of Rapamycin Complex 1-NADPH Oxidase 4 Axis Podocyte p53 Limits the Severity of Experimental Alport Syndrome.Diabetic conditions modulate the adenosine monophosphate-activated protein kinase of podocytes.Low-Dose IL-17 Therapy Prevents and Reverses Diabetic Nephropathy, Metabolic Syndrome, and Associated Organ Fibrosis.Angiotensin II Modulates p130Cas of Podocytes by the Suppression of AMP-Activated Protein Kinase.Increased oxidative stress and apoptosis in the hypothalamus of diabetic male mice in the insulin receptor substrate-2 knockout model.Mammalian target of rapamycin regulates Nox4-mediated podocyte depletion in diabetic renal injury.

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P2860

AMP-activated protein kinase (AMPK) negatively regulates Nox4-dependent activation of p53 and epithelial cell apoptosis in diabetes.

http://www.wikidata.org/entity/Q34333672

description

2010 nî lūn-bûn

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2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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AMP-activated protein kinase ( ...... al cell apoptosis in diabetes.

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AMP-activated protein kinase ( ...... al cell apoptosis in diabetes.

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AMP-activated protein kinase ( ...... al cell apoptosis in diabetes.

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AMP-activated protein kinase ( ...... ial cell apoptosis in diabetes

@en

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Assaad A Eid

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Balakuntalam S Kasinath

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Bridget M Ford

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Goutam Ghosh-Choudhury

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Hanna E Abboud

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Jeffrey L Barnes

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Karen Block

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P2860

p53 has a direct apoptogenic role at the mitochondria

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

The AMP-activated protein kinase--fuel gauge of the mammalian cell?

Adiponectin regulates albuminuria and podocyte function in mice

Activation of PKC-delta and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy

Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases.

Biochemistry and molecular cell biology of diabetic complications

A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

The AMP-activated protein kinase activator AICAR does not induce GLUT4 translocation to transverse tubules but stimulates glucose uptake and p38 mitogen-activated protein kinases alpha and beta in skeletal muscle

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