Unfolding the role of chaperones and chaperonins in human disease.
about
Hereditary spastic paraplegia SPG13 is associated with a mutation in the gene encoding the mitochondrial chaperonin Hsp60Proteomic characterization of an isolated fraction of synthetic proteasome inhibitor (PSI)-induced inclusions in PC12 cells might offer clues to aggresomes as a cellular defensive response against proteasome inhibition by PSI.The ATPases: a new family for a family-based drug design approach.Analysis of the heat shock response in mouse liver reveals transcriptional dependence on the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha).Proteomic changes in the rat brain induced by homogenous irradiation and by the bystander effect resulting from high energy synchrotron X-ray microbeams.Chaperones increase association of tau protein with microtubules.Keratins: guardians of the liver.Regulation of Proteome Maintenance Gene Expression by Activators of Peroxisome Proliferator-Activated Receptor α.Guanidine-HCl dependent structural unfolding of M-crystallin: fluctuating native state like topologies and intermolecular association.Is the transportation highway the right road for hereditary spastic paraplegia?Convergence of heat shock protein 90 with ubiquitin in filamentous alpha-synuclein inclusions of alpha-synucleinopathies.Chemical chaperones--a new concept in drug research.Functional rescue of experimental ischemic optic neuropathy with αB-crystallin.Menin missense mutants associated with multiple endocrine neoplasia type 1 are rapidly degraded via the ubiquitin-proteasome pathway.NMNAT suppresses tau-induced neurodegeneration by promoting clearance of hyperphosphorylated tau oligomers in a Drosophila model of tauopathy.Genetic disorders involving molecular-chaperone genes: a perspective.A Novel Method for Assessing the Chaperone Activity of Proteins.The pathology of cellular anti-stress mechanisms: a new frontier.Mutation in the epsilon subunit of the cytosolic chaperonin-containing t-complex peptide-1 (Cct5) gene causes autosomal recessive mutilating sensory neuropathy with spastic paraplegia.Association of heat-shock proteins in various neurodegenerative disorders: is it a master key to open the therapeutic door?Phenylketonuria: genotype-phenotype correlations based on expression analysis of structural and functional mutations in PAH.Inhibition of insulin amyloid formation by small stress molecules.Heat shock protein 90 indirectly regulates ERK activity by affecting Raf protein metabolism.Transduced human PEP-1-heat shock protein 27 efficiently protects against brain ischemic insult.Hsp90 Maintains the Stability and Function of the Tau Phosphorylating Kinase GSK3β.Genetic testing including targeted gene panel in a diverse clinical population of children with autism spectrum disorder: Findings and implications.HSP70-2 (HSPA1B) is associated with noncognitive symptoms in late-onset Alzheimer's disease.
P2860
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P2860
Unfolding the role of chaperones and chaperonins in human disease.
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Unfolding the role of chaperones and chaperonins in human disease.
@ast
Unfolding the role of chaperones and chaperonins in human disease.
@en
Unfolding the role of chaperones and chaperonins in human disease.
@nl
type
label
Unfolding the role of chaperones and chaperonins in human disease.
@ast
Unfolding the role of chaperones and chaperonins in human disease.
@en
Unfolding the role of chaperones and chaperonins in human disease.
@nl
prefLabel
Unfolding the role of chaperones and chaperonins in human disease.
@ast
Unfolding the role of chaperones and chaperonins in human disease.
@en
Unfolding the role of chaperones and chaperonins in human disease.
@nl
P1433
P1476
Unfolding the role of chaperones and chaperonins in human disease.
@en
P2093
Biesecker LG
Slavotinek AM
P304
P356
10.1016/S0168-9525(01)02413-1
P577
2001-09-01T00:00:00Z