Industrial purification of pharmaceutical antibodies: development, operation, and validation of chromatography processes.
about
Industrialization of mAb production technology: the bioprocessing industry at a crossroadsConformational plasticity of RNA for target recognition as revealed by the 2.15 A crystal structure of a human IgG-aptamer complexRecovery and purification process development for monoclonal antibody productionRNA plasticity and selectivity applicable to therapeutics and novel biosensor developmentVirus filtration of high-concentration monoclonal antibody solutions.Ion exchange chromatography of antibody fragments.Combinatorial de novo design and application of a biomimetic affinity ligand for the purification of human anti-HIV mAb 4E10 from transgenic tobacco.Cation-exchange chromatography of monoclonal antibodies: characterisation of a novel stationary phase designed for production-scale purificationImpact of antibody aggregation on a flowthrough anion-exchange membrane process.Overview on the use of therapeutic antibodies in drug discovery.Porcine circovirus (PCV) removal by Q sepharose fast flow chromatographyA novel approach to monitor clearance of host cell proteins associated with monoclonal antibodies.Plant cell cultures for the production of recombinant proteins.Transgenic plants in the biopharmaceutical market.Expression Cloning and Production of Human Heavy-Chain-Only Antibodies from Murine Transgenic Plasma Cells.Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin GImplementation of advanced technologies in commercial monoclonal antibody production.Native Folding of a Recombinant gpE1/gpE2 Heterodimer Vaccine Antigen from a Precursor Protein Fused with Fc IgG.Aggregates in monoclonal antibody manufacturing processes.State-of-the-art in downstream processing of monoclonal antibodies: process trends in design and validation.Partitioning in aqueous two-phase systems: Analysis of strengths, weaknesses, opportunities and threats.The present state of the art in expression, production and characterization of monoclonal antibodies.Affinity-based precipitation via a bivalent peptidic hapten for the purification of monoclonal antibodies.Feasibility study of semi-selective protein precipitation with salt-tolerant copolymers for industrial purification of therapeutic antibodies.Studying host cell protein interactions with monoclonal antibodies using high throughput protein A chromatography.High-throughput methods for miniaturization and automation of monoclonal antibody purification processes.Effects of increased voltage on resolution in preparative isoelectric focusing of myoglobin varia.Quality by design approach for viral clearance by protein a chromatography.Elucidation of acid-induced unfolding and aggregation of human immunoglobulin IgG1 and IgG2 Fc.Effect of copper sulfate on performance of a serum-free CHO cell culture process and the level of free thiol in the recombinant antibody expressed.Effects of altered FcγR binding on antibody pharmacokinetics in cynomolgus monkeysViral clearance by flow-through mode ion exchange columns and membrane adsorbers.Monoclonal antibody purification using cationic polyelectrolytes: an alternative to column chromatography.Identification and prevention of antibody disulfide bond reduction during cell culture manufacturing.Anion exchange chromatography provides a robust, predictable process to ensure viral safety of biotechnology products.Viral clearance using disposable systems in monoclonal antibody commercial downstream processing.Understanding the mechanism of virus removal by Q sepharose fast flow chromatography during the purification of CHO-cell derived biotherapeutics.Purification of antibody and antibody-fragment from E. coli homogenate using 6,9-diamino-2-ethoxyacridine lactate as precipitation agent.Development of a new bioprocess scheme using frozen seed train intermediates to initiate CHO cell culture manufacturing campaigns.Air sparging for prevention of antibody disulfide bond reduction in harvested CHO cell culture fluid.
P2860
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P2860
Industrial purification of pharmaceutical antibodies: development, operation, and validation of chromatography processes.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Industrial purification of pha ...... n of chromatography processes.
@ast
Industrial purification of pha ...... n of chromatography processes.
@en
Industrial purification of pha ...... n of chromatography processes.
@nl
type
label
Industrial purification of pha ...... n of chromatography processes.
@ast
Industrial purification of pha ...... n of chromatography processes.
@en
Industrial purification of pha ...... n of chromatography processes.
@nl
prefLabel
Industrial purification of pha ...... n of chromatography processes.
@ast
Industrial purification of pha ...... n of chromatography processes.
@en
Industrial purification of pha ...... n of chromatography processes.
@nl
P2093
P2860
P1476
Industrial purification of pha ...... n of chromatography processes.
@en
P2093
Fahrner RL
Feuerhelm D
Knudsen HL
Vanderlaan M
P2860
P304
P356
10.1080/02648725.2001.10648017
P577
2001-01-01T00:00:00Z