Activation of EPAC1/2 is essential for osteoclast formation by modulating NFκB nuclear translocation and actin cytoskeleton rearrangements
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MicroRNA-19b-3p Modulates Japanese Encephalitis Virus-Mediated Inflammation via Targeting RNF11Endogenous adenosine maintains cartilage homeostasis and exogenous adenosine inhibits osteoarthritis progression.The future of EPAC-targeted therapies: agonism versus antagonismBiochemical and pharmacological characterizations of ESI-09 based EPAC inhibitors: defining the ESI-09 "therapeutic window".Apremilast, a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors.Cytoplasmic hnRNPK interacts with GSK3β and is essential for the osteoclast differentiation.Structure-Activity Relationship Studies of Substituted 2-(Isoxazol-3-yl)-2-oxo-N'-phenyl-acetohydrazonoyl Cyanide Analogues: Identification of Potent Exchange Proteins Directly Activated by cAMP (EPAC) Antagonists.Osteoclasts-Key Players in Skeletal Health and Disease.Epac1 agonist decreased inflammatory proteins in retinal endothelial cells, and loss of Epac1 increased inflammatory proteins in the retinal vasculature of mice.MicroRNA-22 negatively regulates poly(I:C)-triggered type I interferon and inflammatory cytokine production via targeting mitochondrial antiviral signaling protein (MAVS).Exchange proteins directly activated by cAMP (EPACs): Emerging therapeutic targets.Exchange factors directly activated by cAMP mediate melanocortin 4 receptor-induced gene expression.Adenosine A2A receptor promotes collagen type III synthesis via β-catenin activation in human dermal fibroblasts.Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development.Suppression of osteoclastogenesis via α2-adrenergic receptors.
P2860
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P2860
Activation of EPAC1/2 is essential for osteoclast formation by modulating NFκB nuclear translocation and actin cytoskeleton rearrangements
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Activation of EPAC1/2 is essen ...... in cytoskeleton rearrangements
@ast
Activation of EPAC1/2 is essen ...... in cytoskeleton rearrangements
@en
Activation of EPAC1/2 is essen ...... in cytoskeleton rearrangements
@nl
type
label
Activation of EPAC1/2 is essen ...... in cytoskeleton rearrangements
@ast
Activation of EPAC1/2 is essen ...... in cytoskeleton rearrangements
@en
Activation of EPAC1/2 is essen ...... in cytoskeleton rearrangements
@nl
prefLabel
Activation of EPAC1/2 is essen ...... in cytoskeleton rearrangements
@ast
Activation of EPAC1/2 is essen ...... in cytoskeleton rearrangements
@en
Activation of EPAC1/2 is essen ...... in cytoskeleton rearrangements
@nl
P2093
P2860
P50
P356
P1433
P1476
Activation of EPAC1/2 is essen ...... in cytoskeleton rearrangements
@en
P2093
Aránzazu Mediero
Bruce N Cronstein
Miguel Perez-Aso
P2860
P304
P356
10.1096/FJ.14-255703
P407
P577
2014-08-13T00:00:00Z