A roadmap for natural product discovery based on large-scale genomics and metabolomics. - Wikidata - thesis-toulmin - TriplyDB

A roadmap for natural product discovery based on large-scale genomics and metabolomics.

A roadmap for natural product discovery based on large-scale genomics and metabolomics.

http://www.wikidata.org/entity/Q34364094

about

Cyclisation mechanisms in the biosynthesis of ribosomally synthesised and post-translationally modified peptides Systems Biology Approaches to Understand Natural Products Biosynthesis Synthetic biology for pharmaceutical drug discovery Structure, Bioactivity, and Resistance Mechanism of Streptomonomicin, an Unusual Lasso Peptide from an Understudied Halophilic Actinomycete Convergent biosynthetic pathways to β-lactam antibiotics Synthetic biology to access and expand nature's chemical diversity Biodiversity, Anti-Trypanosomal Activity Screening, and Metabolomic Profiling of Actinomycetes Isolated from Mediterranean Sponges Molecules to Ecosystems: Actinomycete Natural Products In situ Genomic charting of ribosomally synthesized natural product chemical space facilitates targeted mining An Integrated Metabolomic and Genomic Mining Workflow To Uncover the Biosynthetic Potential of Bacteria Computational approaches to natural product discovery Assembly and clustering of natural antibiotics guides target identification Integration of high-content screening and untargeted metabolomics for comprehensive functional annotation of natural product libraries Elucidating the Rimosamide-Detoxin Natural Product Families and Their Biosynthesis Using Metabolite/Gene Cluster Correlations.Plant metabolic clusters - from genetics to genomics.Screening and identification of novel biologically active natural compounds.Interpreting Microbial Biosynthesis in the Genomic Age: Biological and Practical Considerations.Intraspecies comparison of Streptomyces pratensis genomes reveals high levels of recombination and gene conservation between strains of disparate geographic origin.Draft Genome Sequence of Streptomyces albus Strain NBRC 13014T, the Type Species of the Genus Streptomyces.Multiplexed metagenome mining using short DNA sequence tags facilitates targeted discovery of epoxyketone proteasome inhibitors Molecular networking and pattern-based genome mining improves discovery of biosynthetic gene clusters and their products from Salinispora species.Strain-level diversity of secondary metabolism in Streptomyces albus Synergistic binding of the leader and core peptides by the lantibiotic synthetase HalM2.Minimum Information about a Biosynthetic Gene cluster.Discovery of phosphonic acid natural products by mining the genomes of 10,000 actinomycetes.Expanded natural product diversity revealed by analysis of lanthipeptide-like gene clusters in actinobacteria Linking Biosynthetic Gene Clusters to their Metabolites via Pathway- Targeted Molecular Networking.antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters Genomic insights into the evolution of hybrid isoprenoid biosynthetic gene clusters in the MAR4 marine streptomycete clade Yeast homologous recombination-based promoter engineering for the activation of silent natural product biosynthetic gene clusters.Inhibitory interactions promote frequent bistability among competing bacteria Actinobacteria possessing antimicrobial and antioxidant activities isolated from the pollen of scots pine (Pinus sylvestris) grown on the Baikal shore.Synthetic Biology of Natural Products.New Structural Templates for Clinically Validated and Novel Targets in Antimicrobial Drug Research and Development.Discovery of MRSA active antibiotics using primary sequence from the human microbiome.Genome sequencing and description of Oerskovia enterophila VJag, an agar- and cellulose-degrading bacterium.Application of 3D NMR for Structure Determination of Peptide Natural Products.Metabolic profiling as a tool for prioritizing antimicrobial compounds New Insights into the Biosynthetic Logic of Ribosomally Synthesized and Post-translationally Modified Peptide Natural Products.Metabologenomics: Correlation of Microbial Gene Clusters with Metabolites Drives Discovery of a Nonribosomal Peptide with an Unusual Amino Acid Monomer

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A roadmap for natural product discovery based on large-scale genomics and metabolomics.

http://www.wikidata.org/entity/Q34364094

description

2014 nî lūn-bûn

@nan

2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

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2014年論文

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2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

A roadmap for natural product discovery based on large-scale genomics and metabolomics.

@ast

A roadmap for natural product discovery based on large-scale genomics and metabolomics.

@en

A roadmap for natural product discovery based on large-scale genomics and metabolomics.

@nl

type

label

A roadmap for natural product discovery based on large-scale genomics and metabolomics.

@ast

A roadmap for natural product discovery based on large-scale genomics and metabolomics.

@en

A roadmap for natural product discovery based on large-scale genomics and metabolomics.

@nl

prefLabel

A roadmap for natural product discovery based on large-scale genomics and metabolomics.

@ast

A roadmap for natural product discovery based on large-scale genomics and metabolomics.

@en

A roadmap for natural product discovery based on large-scale genomics and metabolomics.

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Nature Chemical Biology

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A roadmap for natural product discovery based on large-scale genomics and metabolomics.

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Anthony W Goering

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David P Labeda

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James R Doroghazi

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Konstantin A Tchalukov

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Neil L Kelleher

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Robert R Haines

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P2860

ETE: a python Environment for Tree Exploration

Cytoscape: a software environment for integrated models of biomolecular interaction networks

Genome sequencing in microfabricated high-density picolitre reactors

MUSCLE: multiple sequence alignment with high accuracy and high throughput

Evolution of lanthipeptide synthetases

NORINE: a database of nonribosomal peptides

De novo assembly of human genomes with massively parallel short read sequencing

Velvet: algorithms for de novo short read assembly using de Bruijn graphs

Versatile and open software for comparing large genomes

Clustal W and Clustal X version 2.0

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10.1038/NCHEMBIO.1659

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11

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10

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William W Metcalf

Jessica C Albright

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2014-09-28T00:00:00Z

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266254513

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25262415

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4201863

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