about
Interdependence of nutrient metabolism and the circadian clock system: Importance for metabolic healthElectric light, particularly at night, disrupts human circadian rhythmicity: is that a problem?Circadian clock-coupled lung cellular and molecular functions in chronic airway diseasesChemical chronobiology: Toward drugs manipulating time.Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (TH 17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor RORγTherapeutic applications of circadian rhythms for the cardiovascular systemManipulating the circadian and sleep cycles to protect against metabolic diseaseCircadian molecular clock in lung pathophysiologyEmerging models for the molecular basis of mammalian circadian timingTherapeutic Effect of a Synthetic RORα/γ Agonist in an Animal Model of AutismClock genes, pancreatic function, and diabetesDevelopment of a Topical Treatment for Psoriasis Targeting RORγ: From Bench to SkinPharmacological targeting of the mammalian clock regulates sleep architecture and emotional behaviourRev-Erb co-regulates muscle regeneration via tethered interaction with the NF-Y cistromeOverexpression of the Circadian Clock Gene Rev-erbα Affects Murine Bone Mesenchymal Stem Cell Proliferation and Osteogenesis.SIRT1 in the Ventromedial Hypothalamus: A Nutrient Sensor Input Into the Internal TimekeeperAntiobesity Effect of a Small Molecule Repressor of RORγ.Personalized medicine for pathological circadian dysfunctions.Melatonin Contributes to the Seasonality of Multiple Sclerosis Relapses.Potent Effects of Flavonoid Nobiletin on Amplitude, Period, and Phase of the Circadian Clock Rhythm in PER2::LUCIFERASE Mouse Embryonic FibroblastsRORγt(+)Foxp3(+) Cells are an Independent Bifunctional Regulatory T Cell Lineage and Mediate Crescentic GNRetinoic Acid-Related Orphan Receptors (RORs): Regulatory Functions in Immunity, Development, Circadian Rhythm, and Metabolism.Characterization of parasite-specific indels and their proposed relevance for selective anthelminthic drug targeting.Molecular Targets for Small-Molecule Modulators of Circadian Clocks.Segregation of Clock and Non-Clock Regulatory Functions of REV-ERB.Pan-cancer analyses of the nuclear receptor superfamilyMouse aldehyde-oxidase-4 controls diurnal rhythms, fat deposition and locomotor activityROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer.Transgenic Adipose-specific Expression of the Nuclear Receptor RORα Drives a Striking Shift in Fat Distribution and Impairs Glycemic Control.Circadian clock components RORα and Bmal1 mediate the anti-proliferative effect of MLN4924 in osteosarcoma cells.Retinoic-acid-orphan-receptor-C inhibition suppresses Th17 cells and induces thymic aberrations.Clock-Enhancing Small Molecules and Potential Applications in Chronic Diseases and Aging.Molecular mechanisms of the circadian clockwork in mammals.Circadian clock and stress interactions in the molecular biology of psychiatric disorders.Circadian systems biology in Metazoa.RORα modulates semaphorin 3E transcription and neurovascular interaction in pathological retinal angiogenesis.N-Arylsulfonyl Indolines as Retinoic Acid Receptor-Related Orphan Receptor γ (RORγ) Agonists.Nuclear receptors and nonalcoholic fatty liver disease.Emerging drugs affecting skeletal muscle function and mitochondrial biogenesis - Potential implications for sports drug testing programs.Targeting hepatic glucose metabolism in the treatment of type 2 diabetes.
P2860
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P2860
description
2014 nî lūn-bûn
@nan
2014 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մարտին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
REV-ERB and ROR nuclear receptors as drug targets.
@ast
REV-ERB and ROR nuclear receptors as drug targets.
@en
REV-ERB and ROR nuclear receptors as drug targets.
@nl
type
label
REV-ERB and ROR nuclear receptors as drug targets.
@ast
REV-ERB and ROR nuclear receptors as drug targets.
@en
REV-ERB and ROR nuclear receptors as drug targets.
@nl
prefLabel
REV-ERB and ROR nuclear receptors as drug targets.
@ast
REV-ERB and ROR nuclear receptors as drug targets.
@en
REV-ERB and ROR nuclear receptors as drug targets.
@nl
P2860
P356
P1476
REV-ERB and ROR nuclear receptors as drug targets
@en
P2093
Douglas J Kojetin
P2860
P2888
P304
P356
10.1038/NRD4100
P50
P577
2014-03-01T00:00:00Z