Functional interactions and signaling properties of mammalian DNA mismatch repair proteins.
about
The base excision repair enzyme MED1 mediates DNA damage response to antitumor drugs and is associated with mismatch repair system integrityFas-associated death domain protein interacts with methyl-CpG binding domain protein 4: a potential link between genome surveillance and apoptosisActivation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damageInteraction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatinIdentification of the mismatch repair genes PMS2 and MLH1 as p53 target genes by using serial analysis of binding elementsGermline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomasMutations affecting a putative MutLalpha endonuclease motif impact multiple mismatch repair functionsRecognition and binding of mismatch repair proteins at an oncogenic hot spotDose dependent effects on cell cycle checkpoints and DNA repair by bendamustineThe alternating ATPase domains of MutS control DNA mismatch repairA Structural Hinge in Eukaryotic MutY Homologues Mediates Catalytic Activity and Rad9–Rad1–Hus1 Checkpoint Complex InteractionsSomatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cellsStructural, molecular and cellular functions of MSH2 and MSH6 during DNA mismatch repair, damage signaling and other noncanonical activitiesMismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase.Proteolysis of the mismatch repair protein MLH1 by caspase-3 promotes DNA damage-induced apoptosis.Mismatch repair and treatment resistance in ovarian cancer.Direct visualization of asymmetric adenine-nucleotide-induced conformational changes in MutL alpha.Novel PMS1 alleles preferentially affect the repair of primer strand loops during DNA replicationMbd4 inactivation increases Cright-arrowT transition mutations and promotes gastrointestinal tumor formation.Parameters of Reserpine Analogs That Induce MSH2/MSH6-Dependent Cytotoxic ResponseMED1: a central molecule for maintenance of genome integrity and response to DNA damageA role for DNA mismatch repair protein Msh2 in error-prone double-strand-break repair in mammalian chromosomesDimerization of MLH1 and PMS2 limits nuclear localization of MutLalpha.CTG repeat instability and size variation timing in DNA repair-deficient mice.Methylation-induced G(2)/M arrest requires a full complement of the mismatch repair protein hMLH1Complex relationship between mismatch repair proteins and MBD4 during immunoglobulin class switch recombinationIncreased incidence of endometrioid tumors caused by aberrations in E-cadherin promoter of mismatch repair-deficient mice.Is thymidine glycol containing DNA a substrate of E. coli DNA mismatch repair system?A role for DNA mismatch repair in sensing and responding to fluoropyrimidine damage.Histone deacetylase SIRT1 modulates and deacetylates DNA base excision repair enzyme thymine DNA glycosylase.Polymorphisms of mismatch repair gene hMLH1 and hMSH2 and risk of gastric cancer in a Chinese population.Molecular signaling mechanisms of apoptosis in hereditary non-polyposis colorectal cancerPerspective on mutagenesis and repair: the standard model and alternate modes of mutagenesis.Importance of MutL homologue MLH1 and MutS homologue MSH2 expression in Turkish patients with sporadic colorectal cancer.Molecular testing for microsatellite instability and its value in tumor characterization.Accurate homologous recombination is a prominent double-strand break repair pathway in mammalian chromosomes and is modulated by mismatch repair protein Msh2.Prognostic significance of DNA repair proteins MLH1, MSH2 and MGMT expression in non-small-cell lung cancer and precursor lesions.DNA damage, a biomarker of carcinogenesis: its measurement and modulation by diet and environment.The p38 mitogen-activated protein kinase pathway links the DNA mismatch repair system to the G2 checkpoint and to resistance to chemotherapeutic DNA-methylating agentsMLH1 expression sensitises ovarian cancer cells to cell death mediated by XIAP inhibition.
P2860
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P2860
Functional interactions and signaling properties of mammalian DNA mismatch repair proteins.
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Functional interactions and si ...... DNA mismatch repair proteins.
@ast
Functional interactions and si ...... DNA mismatch repair proteins.
@en
Functional interactions and si ...... DNA mismatch repair proteins.
@nl
type
label
Functional interactions and si ...... DNA mismatch repair proteins.
@ast
Functional interactions and si ...... DNA mismatch repair proteins.
@en
Functional interactions and si ...... DNA mismatch repair proteins.
@nl
prefLabel
Functional interactions and si ...... DNA mismatch repair proteins.
@ast
Functional interactions and si ...... DNA mismatch repair proteins.
@en
Functional interactions and si ...... DNA mismatch repair proteins.
@nl
P2860
P356
P1476
Functional interactions and si ...... DNA mismatch repair proteins.
@en
P2093
Bellacosa A
P2860
P2888
P304
P356
10.1038/SJ.CDD.4400948
P577
2001-11-01T00:00:00Z
P5875
P6179
1004325443