The two major human metapneumovirus genetic lineages are highly related antigenically, and the fusion (F) protein is a major contributor to this antigenic relatedness - Wikidata - thesis-toulmin - TriplyDB

The two major human metapneumovirus genetic lineages are highly related antigenically, and the fusion (F) protein is a major contributor to this antigenic relatedness

The two major human metapneumovirus genetic lineages are highly related antigenically, and the fusion (F) protein is a major contributor to this antigenic relatedness

http://www.wikidata.org/entity/Q34439107

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Human Metapneumovirus: lessons learned over the first decade Human metapneumovirus in adults The clinical presentation and outcomes of children infected with newly identified respiratory tract viruses A recombinant human monoclonal antibody to human metapneumovirus fusion protein that neutralizes virus in vitro and is effective therapeutically in vivo.The immune response to human metapneumovirus is associated with aberrant immunity and impaired virus clearance in BALB/c mice Humoral immunity to human metapneumovirus infection in adults Molecular epidemiology and evolution of human respiratory syncytial virus and human metapneumovirus.Population-based incidence of human metapneumovirus infection among hospitalized children.The cotton rat (Sigmodon hispidus) is a permissive small animal model of human metapneumovirus infection, pathogenesis, and protective immunity.Soluble recombinant human metapneumovirus G protein is immunogenic but not protective.Infection of nonhuman primates with recombinant human metapneumovirus lacking the SH, G, or M2-2 protein categorizes each as a nonessential accessory protein and identifies vaccine candidates A wild goose metapneumovirus containing a large attachment glycoprotein is avirulent but immunoprotective in domestic turkeys Progress in the development of human parainfluenza virus vaccines Chimeric recombinant human metapneumoviruses with the nucleoprotein or phosphoprotein open reading frame replaced by that of avian metapneumovirus exhibit improved growth in vitro and attenuation in vivo Cytotoxic T-lymphocyte epitope vaccination protects against human metapneumovirus infection and disease in mice.Severe acute respiratory syndrome coronavirus infection of golden Syrian hamsters.Human Metapneumovirus: An Important Cause of Respiratory Disease in Children and Adults.Genetic variability of attachment (G) and Fusion (F) protein genes of human metapneumovirus strains circulating during 2006-2009 in Kolkata, Eastern India Human metapneumovirus infection in chimpanzees, United States Modification of the trypsin-dependent cleavage activation site of the human metapneumovirus fusion protein to be trypsin independent does not increase replication or spread in rodents or nonhuman primates.The role of human metapneumovirus in upper respiratory tract infections in children: a 20-year experience.Viral replication and lung lesions in BALB/c mice experimentally inoculated with avian metapneumovirus subgroup C isolated from chickens A broadly neutralizing human monoclonal antibody exhibits in vivo efficacy against both human metapneumovirus and respiratory syncytial virus.Nonsegmented negative-strand viruses as vaccine vectors.Serologic cross-reactions between nucleocapsid proteins of human respiratory syncytial virus and human metapneumovirus.Detection and genetic diversity of human metapneumovirus in hospitalized children with acute respiratory infections in India.Human metapneumovirus induces more severe disease and stronger innate immune response in BALB/c mice as compared with respiratory syncytial virus Human metapneumovirus fusion protein vaccines that are immunogenic and protective in cotton rats.Frequent frameshift and point mutations in the SH gene of human metapneumovirus passaged in vitro.Seroprevalence of human respiratory syncytial virus and human metapneumovirus in healthy population analyzed by recombinant fusion protein-based enzyme linked immunosorbent assay.New generation live vaccines against human respiratory syncytial virus designed by reverse genetics.Identification and evaluation of a highly effective fusion inhibitor for human metapneumovirus Epidemiology of human metapneumovirus.Live vaccines for human metapneumovirus designed by reverse genetics.Burden of human metapneumovirus infection in young children.An alphavirus replicon-based human metapneumovirus vaccine is immunogenic and protective in mice and cotton rats.Integrin alphavbeta1 promotes infection by human metapneumovirus.Human metapneumovirus reinfection among children in Thailand determined by ELISA using purified soluble fusion protein.A live attenuated human metapneumovirus vaccine strain provides complete protection against homologous viral infection and cross-protection against heterologous viral infection in BALB/c mice.Human metapneumovirus establishes persistent infection in the lungs of mice and is reactivated by glucocorticoid treatment.

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The two major human metapneumovirus genetic lineages are highly related antigenically, and the fusion (F) protein is a major contributor to this antigenic relatedness

http://www.wikidata.org/entity/Q34439107

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2004 nî lūn-bûn

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2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2004年の論文

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JVI.78.13.6927-6937.2004

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Journal of Virology

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Brian R Murphy

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Emerito Amaro-Carambot

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Jeffrey M Riggs

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Josephine M McAuliffe

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Mario H Skiadopoulos

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Marisa St Claire

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Peter L Collins

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Sonja R Surman

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Stéphane Biacchesi

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Ursula J Buchholz

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P2860

Paramyxovirus RNA synthesis and the requirement for hexamer genome length: the rule of six revisited

Children with respiratory disease associated with metapneumovirus in Hong Kong

Bovine parainfluenza virus type 3 (BPIV3) fusion and hemagglutinin-neuraminidase glycoproteins make an important contribution to the restricted replication of BPIV3 in primates.

Identification of mutations contributing to the temperature-sensitive, cold-adapted, and attenuation phenotypes of the live-attenuated cold-passage 45 (cp45) human parainfluenza virus 3 candidate vaccine.

A newly discovered human pneumovirus isolated from young children with respiratory tract disease.

Molecular cloning and sequence analysis of human parainfluenza type 4A virus HN gene: its irregularities on structure and activities.

Analysis of the genomic sequence of a human metapneumovirus.

The G glycoprotein of human respiratory syncytial viruses of subgroups A and B: extensive sequence divergence between antigenically related proteins.

Human metapneumovirus infections in hospitalized children.

The genome length of human parainfluenza virus type 2 follows the rule of six, and recombinant viruses recovered from non-polyhexameric-length antigenomic cDNAs contain a biased distribution of correcting mutations.

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6927-6937

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10.1128/JVI.78.13.6927-6937.2004

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13

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78

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