Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel. - Wikidata - thesis-toulmin - TriplyDB

Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel.

Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel.

http://www.wikidata.org/entity/Q34466626

about

Control of rapsyn stability by the CUL-3-containing E3 ligase complex Redox regulation of CLIC1 by cysteine residues associated with the putative channel pore Bioorthogonal chemistry: fishing for selectivity in a sea of functionality Expanding the genetic code for biological studies Slow peptide bond formation by proline and other N-alkylamino acids in translation Genetically encoding unnatural amino acids for cellular and neuronal studies The 5-HT3 receptor as a therapeutic target Pathways and Barriers for Ion Translocation through the 5-HT3A Receptor Channel Decrypting the sequence of structural events during the gating transition of pentameric ligand-gated ion channels based on an interpolated elastic network model X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation Stereoelectronic and steric effects in side chains preorganize a protein main chain NMR structure of the transmembrane domain of the n-acetylcholine receptor β2 subunit Structural basis for regulation of the Crk signaling protein by a proline switch.Structural Insights into Substrate Binding by PvFKBP35, a Peptidylprolyl cis-trans Isomerase from the Human Malarial Parasite Plasmodium vivax Structure of the interleukin-2 tyrosine kinase Src homology 2 domain; comparison between X-ray and NMR-derived structures Structure and evolution of the spliceosomal peptidyl-prolyl cis-trans isomerase Cwc27 Allosteric activation mechanism of the cys-loop receptors Recent advances in Cys-loop receptor structure and function Site-directed spin labeling reveals pentameric ligand-gated ion channel gating motions Identification and glycerol-induced correction of misfolding mutations in the X-linked mental retardation gene CASK An Electrostatic Funnel in the GABA-Binding Pathway Interaction of the aromatics Tyr-72/Trp-288 in the interface of the extracellular and transmembrane domains is essential for proton gating of acid-sensing ion channels cis-trans-Amide isomerism of the 3,4-dehydroproline residue, the 'unpuckered' proline Proline cis-trans isomerization controls autoinhibition of a signaling protein.In vivo incorporation of non-canonical amino acids by using the chemical aminoacylation strategy: a broadly applicable mechanistic tool Embedded cholesterol in the nicotinic acetylcholine receptor Detection of discriminative sequence patterns in the neighborhood of proline cis peptide bonds and their functional annotation.Rational design of protein stability: effect of (2S,4R)-4-fluoroproline on the stability and folding pathway of ubiquitin Structural determinants of selective alpha-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP.Targeted molecular dynamics study of C-loop closure and channel gating in nicotinic receptors.High throughput electrophysiology with Xenopus oocytes Mechanism of action of cyclophilin a explored by metadynamics simulations.Molecular dynamics of the proline switch and its role in Crk signaling.Chemical scale studies of the Phe-Pro conserved motif in the cys loop of Cys loop receptors.The cis conformation of proline leads to weaker binding of a p53 peptide to MDM2 compared to trans.Proline isomerization in the C-terminal region of HSP27.Tunable control of polyproline helix (PPII) structure via aromatic electronic effects: an electronic switch of polyproline helix.β Subunit M2-M3 loop conformational changes are uncoupled from α1 β glycine receptor channel gating: implications for human hereditary hyperekplexia.Influence of lithium cations on prolyl peptide bonds.A unified view of the role of electrostatic interactions in modulating the gating of Cys loop receptors.

P2860

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P2860

Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel.

http://www.wikidata.org/entity/Q34466626

description

2005 nî lūn-bûn

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2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

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2005年論文

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2005年论文

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name

Cis-trans isomerization at a p ...... transmitter-gated ion channel.

@ast

Cis-trans isomerization at a p ...... transmitter-gated ion channel.

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Cis-trans isomerization at a p ...... transmitter-gated ion channel.

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type

label

Cis-trans isomerization at a p ...... transmitter-gated ion channel.

@ast

Cis-trans isomerization at a p ...... transmitter-gated ion channel.

@en

Cis-trans isomerization at a p ...... transmitter-gated ion channel.

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prefLabel

Cis-trans isomerization at a p ...... transmitter-gated ion channel.

@ast

Cis-trans isomerization at a p ...... transmitter-gated ion channel.

@en

Cis-trans isomerization at a p ...... transmitter-gated ion channel.

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Cis-trans isomerization at a p ...... otransmitter-gated ion channel

@en

P2093

Darren L Beene

http://www.w3.org/2001/XMLSchema#string

Dennis A Dougherty

http://www.w3.org/2001/XMLSchema#string

Lori W Lee

http://www.w3.org/2001/XMLSchema#string

Sarah C R Lummis

http://www.w3.org/2001/XMLSchema#string

P2860

From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor

Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

Structure and gating mechanism of the acetylcholine receptor pore

Cation-pi interactions in ligand recognition by serotonergic (5-HT3A) and nicotinic acetylcholine receptors: the anomalous binding properties of nicotine

Refined structure of the nicotinic acetylcholine receptor at 4A resolution

Use of Steric Interactions To Control Peptide Turn Geometry. Synthesis of Type VI beta-Turn Mimics with 5-tert-Butylproline.

Hinges, swivels and switches: the role of prolines in signalling via transmembrane alpha-helices.

Coupling of agonist binding to channel gating in the GABA(A) receptor.

Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism

P2888

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248-252

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scholarly article

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10.1038/NATURE04130

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7065

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438

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2005-11-01T00:00:00Z

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7487278

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1023667529

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16281040

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neurotransmitter