Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients. - Wikidata - thesis-toulmin - TriplyDB

Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients.

Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients.

http://www.wikidata.org/entity/Q34470414

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Update on ultrasensitive technologies to facilitate research on blood biomarkers for central nervous system disorders The P42 peptide and Peptide-based therapies for Huntington's disease Neural and mesenchymal stem cells in animal models of Huntington's disease: past experiences and future challenges Molecular diagnostics of neurodegenerative disorders Huntington's disease cerebrospinal fluid seeds aggregation of mutant huntingtin.Neurofilament light protein in blood as a potential biomarker of neurodegeneration in Huntington's disease: a retrospective cohort analysis Cataract-associated P23T γD-crystallin retains a native-like fold in amorphous-looking aggregates formed at physiological pH.Gene suppression strategies for dominantly inherited neurodegenerative diseases: lessons from Huntington's disease and spinocerebellar ataxia.Cerebrospinal Fluid Inflammatory Biomarkers Reflect Clinical Severity in Huntington's Disease Tau or neurofilament light-Which is the more suitable biomarker for Huntington's disease?Study of plasma-derived miRNAs mimic differences in Huntington's disease brain.AMPK activation protects from neuronal dysfunction and vulnerability across nematode, cellular and mouse models of Huntington's disease.Huntington's Disease: The Most Curable Incurable Brain Disorder?Selected CSF biomarkers indicate no evidence of early neuroinflammation in Huntington disease.Cerebrospinal fluid total tau concentration predicts clinical phenotype in Huntington's disease.Mutant huntingtin is secreted via a late endosomal/lysosomal unconventional secretory pathway.Targeting cerebrovascular impairments in Huntington's disease: a novel treatment perspective.Is Huntington's disease a tauopathy?Cerebrospinal Fluid Biomarkers for Huntington's Disease.Faulty splicing and cytoskeleton abnormalities in Huntington's disease.Huntington Disease: Linking Pathogenesis to the Development of Experimental Therapeutics.Huntington's Disease: Calcium Dyshomeostasis and Pathology Models Polyglutamine expansion affects huntingtin conformation in multiple Huntington's disease models.Gene suppression approaches to neurodegeneration.Olesoxime suppresses calpain activation and mutant huntingtin fragmentation in the BACHD rat.Novel allele-specific quantification methods reveal no effects of adult onset CAG repeats on HTT mRNA and protein levels.Therapies targeting DNA and RNA in Huntington's disease.Phosphorylation of huntingtin at residue T3 is decreased in Huntington's disease and modulates mutant huntingtin protein conformation.The Evidence for the Spread and Seeding Capacities of the Mutant Huntingtin Protein in in Vitro Systems and Their Therapeutic Implications.Mutant huntingtin protein expression and blood-spinal cord barrier dysfunction in huntington disease.Validation of Ultrasensitive Mutant Huntingtin Detection in Human Cerebrospinal Fluid by Single Molecule Counting Immunoassay.Cerebrospinal fluid neurogranin and TREM2 in Huntington's disease.Cerebrospinal fluid sCD27 levels indicate active T cell-mediated inflammation in premanifest Huntington's disease.A Critical Evaluation of Wet Biomarkers for Huntington's Disease: Current Status and Ways Forward.Translation of MicroRNA-Based Huntingtin-Lowering Therapies from Preclinical Studies to the Clinic.Salivary levels of total huntingtin are elevated in Huntington's disease patients.Unconventional Secretion and Intercellular Transfer of Mutant Huntingtin.Quantification of Total and Mutant Huntingtin Protein Levels in Biospecimens Using a Novel alphaLISA Assay Quantification of the Light Subunit of Neurofilament Protein in Cerebrospinal Fluid of Huntington's Disease Patients

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Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients.

http://www.wikidata.org/entity/Q34470414

description

2015 nî lūn-bûn

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2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի ապրիլին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

Quantification of mutant hunti ...... Huntington's disease patients.

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Quantification of mutant hunti ...... Huntington's disease patients.

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Quantification of mutant hunti ...... Huntington's disease patients.

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type

label

Quantification of mutant hunti ...... Huntington's disease patients.

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Quantification of mutant hunti ...... Huntington's disease patients.

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Quantification of mutant hunti ...... Huntington's disease patients.

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prefLabel

Quantification of mutant hunti ...... Huntington's disease patients.

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Quantification of mutant hunti ...... Huntington's disease patients.

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Quantification of mutant hunti ...... Huntington's disease patients.

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Journal of Clinical Investigation

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Quantification of mutant hunti ...... Huntington's disease patients.

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Andreas Weiss

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Douglas Macdonald

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James R C Miller

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Nicola Robertson

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Rainer Kuhn

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Roberto Boggio

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Salman Haider

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity

Dramatic mutation instability in HD mouse striatum: does polyglutamine load contribute to cell-specific vulnerability in Huntington's disease?

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression

Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: analysis of 36-month observational data.

Huntington disease: natural history, biomarkers and prospects for therapeutics.

Quantification assays for total and polyglutamine-expanded huntingtin proteins.

Huntington's disease: from molecular pathogenesis to clinical treatment.

Cerebrospinal fluid and plasma biomarkers in Alzheimer disease.

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1979-1986

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10.1172/JCI80743

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5

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125

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Sarah J. Tabrizi

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Henrik Zetterberg

Blair R Leavitt

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2015-04-06T00:00:00Z

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25844897

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Huntington disease

cerebrospinal fluid

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4463213

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