DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function. - Wikidata - thesis-toulmin - TriplyDB

DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function.

DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function.

http://www.wikidata.org/entity/Q34474083

about

ATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to Adaptor Hematopoietic Stem Cell Regulation by Type I and II Interferons in the Pathogenesis of Acquired Aplastic Anemia The Importance of Physiologically Relevant Cell Lines for Studying Virus-Host Interactions Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress.Down-regulated GATA-1 up-regulates interferon regulatory factor 3 in lung adenocarcinoma.cGAS is essential for cellular senescence.Type 1 interferons contribute to the clearance of senescent cell.A new model to study neurodegeneration in ataxia oculomotor apraxia type 2 NKG2D ligands mediate immunosurveillance of senescent cells.Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression Late stages of T cell maturation in the thymus involve NF-κB and tonic type I interferon signaling Interferon-α signaling promotes embryonic HSC maturation.TLR9 re-expression in cancer cells extends the S-phase and stabilizes p16(INK4a) protein expression Cell senescence is an antiviral defense mechanism IFITM1 suppression blocks proliferation and invasion of aromatase inhibitor-resistant breast cancer in vivo by JAK/STAT-mediated induction of p21.Melanocytic nevi and melanoma: unraveling a complex relationship.Negative regulation of type I IFN signaling by phosphorylation of STAT2 on T387.PRDM16 represses the type I interferon response in adipocytes to promote mitochondrial and thermogenic programing.Type I Interferons and Natural Killer Cell Regulation in Cancer.Type I Interferons Control Proliferation and Function of the Intestinal Epithelium.Bone Marrow-Derived Mesenchymal Stem Cells From Patients With Systemic Lupus Erythematosus Have a Senescence-Associated Secretory Phenotype Mediated by a Mitochondrial Antiviral Signaling Protein-Interferon-β Feedback Loop.Modulating Both Tumor Cell Death and Innate Immunity Is Essential for Improving Radiation Therapy Effectiveness.DNA repair and systemic lupus erythematosus.Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence.Reduced dynamic range of antiviral innate immune responses in aging.Lentiviral vectors escape innate sensing but trigger p53 in human hematopoietic stem and progenitor cells.Age-associated mRNA expression changes in bovine endometrial cells in vitro.Histone chaperone HIRA deposits histone H3.3 onto foreign viral DNA and contributes to anti-viral intrinsic immunity.IFN-1 Bid crosstalk: foe or friend to stem cells.ATM-activated autotaxin (ATX) propagates inflammation and DNA damage in lung epithelial cells: a new mode of action for silica-induced DNA damage?Downregulation of B-myb promotes senescence via the ROS-mediated p53/p21 pathway, in vascular endothelial cells.Up-regulation of IRF-3 expression through GATA-1 acetylation by histone deacetylase inhibitor in lung adenocarcinoma A549 cells.Distinct Effects of Type I and III Interferons on Enteric Viruses.Cytosolic sensing of immuno-stimulatory DNA, the enemy within.Ataxia telangiectasia syndrome: moonlighting ATM.PIKKing a way to regulate inflammation.Fetal and Maternal Innate Immunity Receptors Have Opposing Effects on the Severity of Experimental Malaria in Pregnancy: Beneficial Roles for Fetus-Derived Toll-Like Receptor 4 and Type I Interferon Receptor 1.A Cell-Intrinsic Interferon-like Response Links Replication Stress to Cellular Aging Caused by Progerin.MLL5 suppresses antiviral innate immune response by facilitating STUB1-mediated RIG-I degradation.Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells.

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P2860

DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function.

http://www.wikidata.org/entity/Q34474083

description

2015 nî lūn-bûn

@nan

2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2015年の論文

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2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

name

DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function.

@ast

DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function.

@en

DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function.

@nl

type

label

DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function.

@ast

DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function.

@en

DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function.

@nl

prefLabel

DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function.

@ast

DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function.

@en

DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function.

@nl

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J.CELREP.2015.03.069

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DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function.

@en

P2093

Bin Zhao

http://www.w3.org/2001/XMLSchema#string

Christopher J Carbone

http://www.w3.org/2001/XMLSchema#string

F Brad Johnson

http://www.w3.org/2001/XMLSchema#string

Hui Zheng

http://www.w3.org/2001/XMLSchema#string

Kanstantsin V Katlinski

http://www.w3.org/2001/XMLSchema#string

Manti Guha

http://www.w3.org/2001/XMLSchema#string

Ning Li

http://www.w3.org/2001/XMLSchema#string

Qijun Chen

http://www.w3.org/2001/XMLSchema#string

Qiujing Yu

http://www.w3.org/2001/XMLSchema#string

Roger A Greenberg

http://www.w3.org/2001/XMLSchema#string

P2860

ATM-dependent phosphorylation of ATF2 is required for the DNA damage response

PKCε promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria

ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks

Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation

DNA damage signaling and p53-dependent senescence after prolonged beta-interferon stimulation

Trex1 prevents cell-intrinsic initiation of autoimmunity

Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination

Activation of interferon regulatory factor 3 in response to DNA-damaging agents

Viruses and interferon: a fight for supremacy

Cytoplasmic DNA innate immune pathways

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785-797

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scholarly article

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10.1016/J.CELREP.2015.03.069

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5

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11

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Christopher J. Lengner

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2015-04-23T00:00:00Z

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275662233

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4426031

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