Review: contribution of transgenic models to understanding human prion disease.
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Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disordersTransgenic Rabbits Expressing Ovine PrP Are Susceptible to ScrapieStrain specific resistance to murine scrapie associated with a naturally occurring human prion protein polymorphism at residue 171.Transmissibility of caprine scrapie in ovine transgenic mice.Mouse-hamster chimeric prion protein (PrP) devoid of N-terminal residues 23-88 restores susceptibility to 22L prions, but not to RML prions in PrP-knockout miceA naturally occurring variant of the human prion protein completely prevents prion disease.A novel and rapid method for obtaining high titre intact prion strains from mammalian brain.Soluble Aβ seeds are potent inducers of cerebral β-amyloid depositionTransmission Properties of Human PrP 102L Prions Challenge the Relevance of Mouse Models of GSS.Identification of I137M and other mutations that modulate incubation periods for two human prion strains.Iatrogenic CJD due to pituitary-derived growth hormone with genetically determined incubation times of up to 40 years.Mutated but Not Deleted Ovine PrP(C) N-Terminal Polybasic Region Strongly Interferes with Prion Propagation in Transgenic MiceAtypical scrapie prions from sheep and lack of disease in transgenic mice overexpressing human prion protein.Prion disease: experimental models and reality.The amyloid state of proteins in human diseases.Role of proteomics in understanding prion infection.Prion disease: a tale of folds and strains.Myelin damage due to local quantitative abnormalities in normal prion levels: evidence from subacute combined degeneration and multiple sclerosis.Inflammation in neurodegenerative diseases--an update.Mechanisms of prion-induced neurodegeneration.Mammalian prions and their wider relevance in neurodegenerative diseases.Effects of prion protein devoid of the N-terminal residues 25-50 on prion pathogenesis in mice.Sporadic Creutzfeldt-Jakob Disease: Prion Pathology in Medulla Oblongata-Possible Routes of Infection and Host Susceptibility.Genetic resistance to transmissible spongiform encephalopathies (TSE) in goatsPrion Protein Devoid of the Octapeptide Repeat Region Delays Bovine Spongiform Encephalopathy Pathogenesis in Mice.Methods for Molecular Diagnosis of Human Prion Disease.Experimental sheep BSE prions generate the vCJD phenotype when serially passaged in transgenic mice expressing human prion protein.Evaluating the causality of novel sequence variants in the prion protein gene by example
P2860
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P2860
Review: contribution of transgenic models to understanding human prion disease.
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2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Review: contribution of transgenic models to understanding human prion disease.
@ast
Review: contribution of transgenic models to understanding human prion disease.
@en
Review: contribution of transgenic models to understanding human prion disease.
@nl
type
label
Review: contribution of transgenic models to understanding human prion disease.
@ast
Review: contribution of transgenic models to understanding human prion disease.
@en
Review: contribution of transgenic models to understanding human prion disease.
@nl
prefLabel
Review: contribution of transgenic models to understanding human prion disease.
@ast
Review: contribution of transgenic models to understanding human prion disease.
@en
Review: contribution of transgenic models to understanding human prion disease.
@nl
P2860
P921
P1476
Review: contribution of transgenic models to understanding human prion disease
@en
P2093
J Collinge
P2860
P304
P356
10.1111/J.1365-2990.2010.01129.X
P5008
P577
2010-12-01T00:00:00Z