PD-1 inhibits antiviral immunity at the effector phase in the liver. - Wikidata - thesis-toulmin - TriplyDB

PD-1 inhibits antiviral immunity at the effector phase in the liver.

PD-1 inhibits antiviral immunity at the effector phase in the liver.

http://www.wikidata.org/entity/Q34535179

about

Emerging mechanisms of immune regulation: the extended B7 family and regulatory T cells Pembrolizumab Immune checkpoint blockade in hepatocellular carcinoma: current progress and future directions The expression of PD-1 ligands and their involvement in regulation of T cell functions in acute and chronic woodchuck hepatitis virus infection Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression Functional Restoration of HCV-Specific CD8 T Cells by PD-1 Blockade Is Defined by PD-1 Expression and Compartmentalization Costimulatory molecule programmed death-1 in the cytotoxic response during chronic hepatitis C The CD8 T-cell response during tolerance induction in liver transplantation The Next Immune-Checkpoint Inhibitors: PD-1/PD-L1 Blockade in Melanoma Restoring function in exhausted CD8 T cells during chronic viral infection Lipidoid Nanoparticles Containing PD-L1 siRNA Delivered In Vivo Enter Kupffer Cells and Enhance NK and CD8(+) T Cell-mediated Hepatic Antiviral Immunity.Blockade of PD-1/B7-H1 interaction restores effector CD8+ T cell responses in a hepatitis C virus core murine model An IFN-gamma-IL-18 signaling loop accelerates memory CD8+ T cell proliferation.Hepatitis B Virus Immunopathology, Model Systems, and Current Therapies Octamer binding protein 2 (Oct2) regulates PD-L2 gene expression in B-1 cells through lineage-specific activity of a unique, intronic promoter.Natural course of chronic hepatitis B is characterized by changing patterns of programmed death type-1 of CD8-positive T cells.Respiratory syncytial virus is associated with an inflammatory response in lungs and architectural remodeling of lung-draining lymph nodes of newborn lambs.CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition IL-2high tissue-resident T cells in the human liver: Sentinels for hepatotropic infection.PD-1, gender, and autoimmunity.Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes.PD-1/B7-H1 interaction contribute to the spontaneous acceptance of mouse liver allograft Programmed death (PD)-1-deficient mice are extremely sensitive to murine hepatitis virus strain-3 (MHV-3) infection.Alloantigen expression on non-hematopoietic cells reduces graft-versus-leukemia effects in mice.PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice.Target-dependent B7-H1 regulation contributes to clearance of central nervous system infection and dampens morbidity.Targeting immune co-stimulatory effects of PD-L1 and PD-L2 might represent an effective therapeutic strategy in stroke.PD-1 blockage reverses immune dysfunction and hepatitis B viral persistence in a mouse animal model.Liver immunology.Longitudinal fluctuations in PD1 and PD-L1 expression in association with changes in anti-viral immune response in chronic hepatitis B.Expression of the interleukin-7 receptor alpha chain (CD127) on virus-specific CD8+ T cells identifies functionally and phenotypically defined memory T cells during acute resolving hepatitis B virus infection Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells Expression of PD-L1 and PD-L2 on human macrophages is up-regulated by HIV-1 and differentially modulated by IL-10 PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection.RSV-induced bronchial epithelial cell PD-L1 expression inhibits CD8+ T cell nonspecific antiviral activity.The hepatitis B virus-associated tumor microenvironment in hepatocellular carcinoma.Enhanced antiviral T cell function in the absence of B7-H1 is insufficient to prevent persistence but exacerbates axonal bystander damage during viral encephalomyelitis.Immunostaining of PD-1/PD-Ls in liver tissues of patients with hepatitis and hepatocellular carcinoma.Kupffer cell suppression of CD8+ T cells in human hepatocellular carcinoma is mediated by B7-H1/programmed death-1 interactions Immunotherapy of murine retrovirus-induced acquired immunodeficiency by CD4 T regulatory cell depletion and PD-1 blockade

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P2860

PD-1 inhibits antiviral immunity at the effector phase in the liver.

http://www.wikidata.org/entity/Q34535179

description

2003 nî lūn-bûn

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2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2003 թվականի հուլիսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

@zh-tw

2003年论文

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name

PD-1 inhibits antiviral immunity at the effector phase in the liver.

@ast

PD-1 inhibits antiviral immunity at the effector phase in the liver.

@en

PD-1 inhibits antiviral immunity at the effector phase in the liver.

@nl

type

label

PD-1 inhibits antiviral immunity at the effector phase in the liver.

@ast

PD-1 inhibits antiviral immunity at the effector phase in the liver.

@en

PD-1 inhibits antiviral immunity at the effector phase in the liver.

@nl

prefLabel

PD-1 inhibits antiviral immunity at the effector phase in the liver.

@ast

PD-1 inhibits antiviral immunity at the effector phase in the liver.

@en

PD-1 inhibits antiviral immunity at the effector phase in the liver.

@nl

P1433

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P1433

Journal of Experimental Medicine

P1476

PD-1 inhibits antiviral immunity at the effector phase in the liver.

@en

P2093

Masaya Ikegawa

http://www.w3.org/2001/XMLSchema#string

Seigo Terawaki

http://www.w3.org/2001/XMLSchema#string

Taku Okazaki

http://www.w3.org/2001/XMLSchema#string

Yoshiko Iwai

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P2860

B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion

B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells

Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death

CD28/B7 system of T cell costimulation

Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7

Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

Local control of the immune response in the liver

Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

P304

39-50

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scholarly article

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10.1084/JEM.20022235

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1

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198

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2003-07-01T00:00:00Z

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10673833

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12847136

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2196084

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