Futsch/MAP1B mRNA is a translational target of TDP-43 and is neuroprotective in a Drosophila model of amyotrophic lateral sclerosis.
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The Presynaptic Microtubule Cytoskeleton in Physiological and Pathological Conditions: Lessons from Drosophila Fragile X Syndrome and Hereditary Spastic ParaplegiasDysregulated axonal RNA translation in amyotrophic lateral sclerosisThe Crossroads of Synaptic Growth Signaling, Membrane Traffic and Neurological Disease: Insights from DrosophilaA Case for Microtubule Vulnerability in Amyotrophic Lateral Sclerosis: Altered Dynamics During DiseaseGene expression profiling for human iPS-derived motor neurons from sporadic ALS patients reveals a strong association between mitochondrial functions and neurodegeneration.Role of BMP receptor traffic in synaptic growth defects in an ALS model.Altered mRNP granule dynamics in FTLD pathogenesis.TDP-43 and FUS en route from the nucleus to the cytoplasm.Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathwaysFragile X protein mitigates TDP-43 toxicity by remodeling RNA granules and restoring translation.Co-regulation of mRNA translation by TDP-43 and Fragile X Syndrome protein FMRPSplicing factors act as genetic modulators of TDP-43 production in a new autoregulatory TDP-43 Drosophila model.FUS inclusions disrupt RNA localization by sequestering kinesin-1 and inhibiting microtubule detyrosination.Stability properties of neuronal microtubules.Physiological functions and pathobiology of TDP-43 and FUS/TLS proteins.Neurobiology of axonal transport defects in motor neuron diseases: Opportunities for translational research?Control of mRNA Translation in ALS ProteinopathyTDP-43 and Cytoskeletal Proteins in ALS.Reduced TDP-43 Expression Improves Neuronal Activities in a Drosophila Model of Perry Syndrome.Failure to Deliver and Translate-New Insights into RNA Dysregulation in ALS.Microtubules in health and degenerative disease of the nervous system.FUS toxicity is rescued by the modulation of lncRNA hsrω expression in Drosophila melanogaster.Post-transcriptional Inhibition of Hsc70-4/HSPA8 Expression Leads to Synaptic Vesicle Cycling Defects in Multiple Models of ALS.In Vivo Translatome Profiling in Spinal Muscular Atrophy Reveals a Role for SMN Protein in Ribosome Biology.TDP-43 misexpression causes defects in dendritic growth.TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD.The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity.Increased cytoplasmic TDP-43 reduces global protein synthesis by interacting with RACK1 on polyribosomes.mRNP assembly, axonal transport, and local translation in neurodegenerative diseases.Biology and Pathobiology of TDP-43 and Emergent Therapeutic Strategies.Synaptic Paths to Neurodegeneration: The Emerging Role of TDP-43 and FUS in Synaptic Functions.Linking hnRNP Function to ALS and FTD Pathology.Medium-Chain Fatty Acids, Beta-Hydroxybutyric Acid and Genetic Modulation of the Carnitine Shuttle Are Protective in a Drosophila Model of ALS Based on TDP-43.TDP-43 causes neurotoxicity and cytoskeletal dysfunction in primary cortical neurons.as a Model for Assessing the Function of RNA-Binding Proteins during Neurogenesis and Neurological DiseaseUnraveling the Pathways to Neuronal Homeostasis and Disease: Mechanistic Insights into the Role of RNA-Binding Proteins and Associated Factors
P2860
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P2860
Futsch/MAP1B mRNA is a translational target of TDP-43 and is neuroprotective in a Drosophila model of amyotrophic lateral sclerosis.
description
2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Futsch/MAP1B mRNA is a transla ...... amyotrophic lateral sclerosis.
@ast
Futsch/MAP1B mRNA is a transla ...... amyotrophic lateral sclerosis.
@en
Futsch/MAP1B mRNA is a transla ...... amyotrophic lateral sclerosis.
@nl
type
label
Futsch/MAP1B mRNA is a transla ...... amyotrophic lateral sclerosis.
@ast
Futsch/MAP1B mRNA is a transla ...... amyotrophic lateral sclerosis.
@en
Futsch/MAP1B mRNA is a transla ...... amyotrophic lateral sclerosis.
@nl
prefLabel
Futsch/MAP1B mRNA is a transla ...... amyotrophic lateral sclerosis.
@ast
Futsch/MAP1B mRNA is a transla ...... amyotrophic lateral sclerosis.
@en
Futsch/MAP1B mRNA is a transla ...... amyotrophic lateral sclerosis.
@nl
P2093
P2860
P1476
Futsch/MAP1B mRNA is a transla ...... amyotrophic lateral sclerosis.
@en
P2093
Alyssa N Coyne
Antony Pearson
Bhavani Bagevalu Siddegowda
Jeffrey Johannesmeyer
Patricia S Estes
Robert Bowser
Scott G Daniel
Tina Kovalik
P2860
P304
15962-15974
P356
10.1523/JNEUROSCI.2526-14.2014
P407
P577
2014-11-01T00:00:00Z