Altered axonal mitochondrial transport in the pathogenesis of Charcot-Marie-Tooth disease from mitofusin 2 mutations.
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Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission.Leucine-rich repeat kinase 2 disturbs mitochondrial dynamics via Dynamin-like proteinFunction Over Form: Modeling Groups of Inherited Neurological Conditions in ZebrafishTransporting mitochondria in neuronsCharcot-Marie-Tooth disease and intracellular trafficNovel subcellular localization for α-synuclein: possible functional consequencesMitochondrial form and functionThe axonal transport of mitochondriaInner membrane fusion mediates spatial distribution of axonal mitochondriaMitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration.Impulse conduction increases mitochondrial transport in adult mammalian peripheral nerves in vivoAmyloid precursor protein-mediated endocytic pathway disruption induces axonal dysfunction and neurodegenerationDisruption of mitochondrial DNA replication in Drosophila increases mitochondrial fast axonal transport in vivoA mutation associated with CMT2A neuropathy causes defects in Fzo1 GTP hydrolysis, ubiquitylation, and protein turnover.Mitochondrial fragmentation in neurodegenerationA novel deletion in the GTPase domain of OPA1 causes defects in mitochondrial morphology and distribution, but not in functionMitochondrial stress and the pathogenesis of diabetic neuropathyNutrient excess and altered mitochondrial proteome and function contribute to neurodegeneration in diabetesMorphological and bioenergetic demands underlying the mitophagy in post-mitotic neurons: the pink-parkin pathwayMitofusin2 mutations disrupt axonal mitochondrial positioning and promote axon degenerationPINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondriaMitochondria: in sickness and in healthPositively charged residues within the MYO19 MyMOMA domain are essential for proper localization of MYO19 to the mitochondrial outer membrane.Hypergonadotropic hypogonadism, progressive early-onset spinocerebellar ataxia, and late-onset sensorineural hearing loss: case report and literature review.Mutation of FIG4 causes a rapidly progressive, asymmetric neuronal degeneration.Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetesActivity-dependent regulation of mitochondrial motility by calcium and Na/K-ATPase at nodes of Ranvier of myelinated nerves.Axon degeneration and PGC-1α-mediated protection in a zebrafish model of α-synuclein toxicityThe Armc10/SVH gene: genome context, regulation of mitochondrial dynamics and protection against Aβ-induced mitochondrial fragmentationMitochondrial dysfunction and apoptosis in cumulus cells of type I diabetic miceMitochondrial fusion is increased by the nuclear coactivator PGC-1betaSmall molecule inhibitors of mitochondrial division: tools that translate basic biological research into medicine.Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complexMitochondrial fragmentation leads to intracellular acidification in Caenorhabditis elegans and mammalian cells.Retrograde axonal transport: pathways to cell death?A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease.Defects in mitochondrial axonal transport and membrane potential without increased reactive oxygen species production in a Drosophila model of Friedreich ataxiaDistinct pathogenic processes between Fig4-deficient motor and sensory neurons.Hereditary Motor and Sensory Neuropathy Type VI with Bilateral Middle Cerebellar Peduncle Involvement.SOD1 targeted to the mitochondrial intermembrane space prevents motor neuropathy in the Sod1 knockout mouse.
P2860
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P2860
Altered axonal mitochondrial transport in the pathogenesis of Charcot-Marie-Tooth disease from mitofusin 2 mutations.
description
2007 nî lūn-bûn
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2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
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2007年学术文章
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2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
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2007年學術文章
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name
Altered axonal mitochondrial t ...... se from mitofusin 2 mutations.
@ast
Altered axonal mitochondrial t ...... se from mitofusin 2 mutations.
@en
Altered axonal mitochondrial t ...... se from mitofusin 2 mutations.
@nl
type
label
Altered axonal mitochondrial t ...... se from mitofusin 2 mutations.
@ast
Altered axonal mitochondrial t ...... se from mitofusin 2 mutations.
@en
Altered axonal mitochondrial t ...... se from mitofusin 2 mutations.
@nl
prefLabel
Altered axonal mitochondrial t ...... se from mitofusin 2 mutations.
@ast
Altered axonal mitochondrial t ...... se from mitofusin 2 mutations.
@en
Altered axonal mitochondrial t ...... se from mitofusin 2 mutations.
@nl
P2093
P1476
Altered axonal mitochondrial t ...... se from mitofusin 2 mutations.
@en
P2093
Alan Pestronk
Robert E Schmidt
Robert H Baloh
P304
P356
10.1523/JNEUROSCI.4798-06.2007
P407
P577
2007-01-01T00:00:00Z