High-frequency expression of a conserved kappa light-chain variable-region gene in chronic lymphocytic leukemia.
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Autoantibody-associated kappa light chain variable region gene expressed in chronic lymphocytic leukemia with little or no somatic mutation. Implications for etiology and immunotherapySomatic hypermutations confer rheumatoid factor activity in hepatitis C virus-associated mixed cryoglobulinemiaPreferential rearrangement of V kappa 4 gene segments in pre-B cell lines.Evidence of antigen receptor-influenced oligoclonal B lymphocyte expansion in the synovium of a patient with longstanding rheumatoid arthritis.Evidence that the V kappa III gene usage is nonstochastic in both adult and newborn peripheral B cells and that peripheral CD5+ adult B cells are oligoclonal.New roles for rheumatoid factor.Relationship of the CD5 B cell to human tonsillar lymphocytes that express autoantibody-associated cross-reactive idiotypesDevelopmentally restricted immunoglobulin heavy chain variable region gene expressed at high frequency in chronic lymphocytic leukemia.Idiotypic and subgroup analysis of human monoclonal rheumatoid factors. Implications for structural and genetic basis of autoantibodies in humans.CD5 negative IGM rheumatoid factor B cells in B-chronic lymphocytic leukemia and benign mixed cryoglobulinemia.Immunoglobulin V gene expression in CD5 B-cell malignancies.Specificity and idiotope expression of IgM produced by CD5+ and CD5- cord blood B-cell clones.Human antibody responses to bacterial antigens: studies of a model conventional antigen and a proposed model B cell superantigen.CD5-positive B-cell malignancies frequently express cross-reactive idiotypes associated with IgM autoantibodiesEvidence for somatic selection of natural autoantibodies.Extensive and selective mutation of a rearranged VH5 gene in human B cell chronic lymphocytic leukemia.Complete sequence of the genes encoding the VH and VL regions of low- and high-affinity monoclonal IgM and IgA1 rheumatoid factors produced by CD5+ B cells from a rheumatoid arthritis patient.Uniform high frequency expression of autoantibody-associated crossreactive idiotypes in the primary B cell follicles of human fetal spleen.Isolation and characterization of a light chain variable region gene for human rheumatoid factorsLack of extensive mutations in the VH5 genes used in common B cell chronic lymphocytic leukemia.Somatic diversification and selection of immunoglobulin heavy and light chain variable region genes in IgG+ CD5+ chronic lymphocytic leukemia B cells.Malignant CD5 B cells--biased immunoglobulin variable gene usage and autoantibody production.Autoantibodies and the fetal antibody repertoire.Polymorphisms of immunologically relevant loci in human disease. Autoimmunity and human heavy chain variable regions.Defining Natural Antibodies.Human CD5-positive B cells in lymphoid malignancy and connective tissue diseases.Selective expression of a VHIV subfamily of immunoglobulin genes in human CD5+ B lymphocytes from cord blood.Somatic mutations in the variable regions of a human IgG anti-double-stranded DNA autoantibody suggest a role for antigen in the induction of systemic lupus erythematosus.A human anti-insulin IgG autoantibody apparently arises through clonal selection from an insulin-specific "germ-line" natural antibody template. Analysis by V gene segment reassortment and site-directed mutagenesis.Immunocytochemical detection of kappa and lambda light chain V region subgroups in human B-cell malignancies.Effect of 51p1-related gene copy number (V1-69 locus) on production of hepatitis C-associated cryoglobulins.Immunoglobulin Gene Rearrangement and Expression in B-CLL.In vivo binding of mouse IgG via polyreactive surface IgM abrogates progressive lymphocytosis in prolymphocytic leukemia.Editorial: Natural Antibodies in Health and Disease.Analysis of multidrug-resistance (MDR-1) glycoprotein and CD56 expression to separate monoclonal gammopathy from multiple myeloma.Amyloidosis associated with chronic lymphocytic leukemia
P2860
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P2860
High-frequency expression of a conserved kappa light-chain variable-region gene in chronic lymphocytic leukemia.
description
1987 nî lūn-bûn
@nan
1987 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1987 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
name
High-frequency expression of a ...... chronic lymphocytic leukemia.
@ast
High-frequency expression of a ...... chronic lymphocytic leukemia.
@en
High-frequency expression of a ...... chronic lymphocytic leukemia.
@nl
type
label
High-frequency expression of a ...... chronic lymphocytic leukemia.
@ast
High-frequency expression of a ...... chronic lymphocytic leukemia.
@en
High-frequency expression of a ...... chronic lymphocytic leukemia.
@nl
prefLabel
High-frequency expression of a ...... chronic lymphocytic leukemia.
@ast
High-frequency expression of a ...... chronic lymphocytic leukemia.
@en
High-frequency expression of a ...... chronic lymphocytic leukemia.
@nl
P2093
P2860
P356
P1476
High-frequency expression of a ...... chronic lymphocytic leukemia.
@en
P2093
P2860
P304
P356
10.1073/PNAS.84.9.2916
P407
P577
1987-05-01T00:00:00Z