Protective immunity against tuberculosis induced by vaccination with major extracellular proteins of Mycobacterium tuberculosis.
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The mycobacterial 38-kilodalton glycolipoprotein antigen activates the mitogen-activated protein kinase pathway and release of proinflammatory cytokines through Toll-like receptors 2 and 4 in human monocytesProtective efficacy of a DNA vaccine encoding antigen 85A from Mycobacterium bovis BCG against Buruli ulcerA new vaccine against tuberculosis affords greater survival after challenge than the current vaccine in the guinea pig model of pulmonary tuberculosisA new recombinant bacille Calmette-Guérin vaccine safely induces significantly enhanced tuberculosis-specific immunity in human volunteersRecombinant bacillus calmette-guerin (BCG) vaccines expressing the Mycobacterium tuberculosis 30-kDa major secretory protein induce greater protective immunity against tuberculosis than conventional BCG vaccines in a highly susceptible animal modelHost immune responses to mycobacterial antigens and their implications for the development of a vaccine to control tuberculosisVaccination with a BCG strain overexpressing Ag85B protects cattle against Mycobacterium bovis challengeEpitope focus, clonal composition and Th1 phenotype of the human CD4 response to the secretory mycobacterial antigen Ag85MTC28, a novel 28-kilodalton proline-rich secreted antigen specific for the Mycobacterium tuberculosis complexIdentification of genes encoding exported Mycobacterium tuberculosis proteins using a Tn552'phoA in vitro transposition systemCloning, expression, and immunological evaluation of two putative secreted serine protease antigens of Mycobacterium tuberculosisNovel insights into the genetics, biochemistry, and immunocytochemistry of the 30-kilodalton major extracellular protein of Mycobacterium tuberculosisGlutamine synthetase GlnA1 is essential for growth of Mycobacterium tuberculosis in human THP-1 macrophages and guinea pigsHigh-level heterologous expression and secretion in rapidly growing nonpathogenic mycobacteria of four major Mycobacterium tuberculosis extracellular proteins considered to be leading vaccine candidates and drug targetsProperties of the 40 kDa antigen of Mycobacterium tuberculosis, a functional L-alanine dehydrogenaseIsoniazid induces expression of the antigen 85 complex in Mycobacterium tuberculosisIdentification of fur, aconitase, and other proteins expressed by Mycobacterium tuberculosis under conditions of low and high concentrations of iron by combined two-dimensional gel electrophoresis and mass spectrometryAn increase in expression of a Mycobacterium tuberculosis mycolyl transferase gene (fbpB) occurs early after infection of human monocytesHuman and murine immune responses to a novel Leishmania major recombinant protein encoded by members of a multicopy gene family.Boosting BCG-primed mice with chimeric DNA vaccine HG856A induces potent multifunctional T cell responses and enhanced protection against Mycobacterium tuberculosis.Identification by mass spectrometry of CD8(+)-T-cell Mycobacterium tuberculosis epitopes within the Rv0341 gene productDecreased capacity of recombinant 45/47-kDa molecules (Apa) of Mycobacterium tuberculosis to stimulate T lymphocyte responses related to changes in their mannosylation pattern.Cloning of the gene encoding a 22-kilodalton cell surface antigen of Mycobacterium bovis BCG and analysis of its potential for DNA vaccination against tuberculosisHost-adaptation of Francisella tularensis alters the bacterium's surface-carbohydrates to hinder effectors of innate and adaptive immunity.Evidence for a partial redundancy of the fibronectin-binding proteins for the transfer of mycoloyl residues onto the cell wall arabinogalactan termini of Mycobacterium tuberculosis.High extracellular levels of Mycobacterium tuberculosis glutamine synthetase and superoxide dismutase in actively growing cultures are due to high expression and extracellular stability rather than to a protein-specific export mechanism.Whole genome identification of Mycobacterium tuberculosis vaccine candidates by comprehensive data mining and bioinformatic analysesA single strain of Mycobacterium bovis bacillus Calmette-Guérin (BCG) grown in two different media evokes distinct humoral immune responses in mice.Specific and randomly derived immunoactive peptide mimotopes of mycobacterial antigensNovel genome polymorphisms in BCG vaccine strains and impact on efficacy.Identification of Mycobacterium tuberculosis vaccine candidates using human CD4+ T-cells expression cloning.Mycobacterium tuberculosis Rv0679c protein sequences involved in host-cell infection: potential TB vaccine candidate antigen.Polyclonal activation of naïve T cells by urease deficient-recombinant BCG that produced protein complex composed of heat shock protein 70, CysO and major membrane protein-IIMycobacterium bovis BCG induces similar immune responses and protection by rectal and parenteral immunization routes.Cytokine profiles for peripheral blood lymphocytes from patients with active pulmonary tuberculosis and healthy household contacts in response to the 30-kilodalton antigen of Mycobacterium tuberculosisSuperior efficacy of secreted over somatic antigen display in recombinant Salmonella vaccine induced protection against listeriosisEvaluation of new vaccines in the mouse and guinea pig model of tuberculosisTwo-dimensional electrophoresis for analysis of Mycobacterium tuberculosis culture filtrate and purification and characterization of six novel proteins.Peripheral blood and pleural fluid mononuclear cell responses to low-molecular-mass secretory polypeptides of Mycobacterium tuberculosis in human models of immunity to tuberculosis.T-cell epitope mapping of the three most abundant extracellular proteins of Mycobacterium tuberculosis in outbred guinea pigs.
P2860
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P2860
Protective immunity against tuberculosis induced by vaccination with major extracellular proteins of Mycobacterium tuberculosis.
description
1995 nî lūn-bûn
@nan
1995 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Protective immunity against tu ...... of Mycobacterium tuberculosis.
@ast
Protective immunity against tu ...... of Mycobacterium tuberculosis.
@en
Protective immunity against tu ...... of Mycobacterium tuberculosis.
@nl
type
label
Protective immunity against tu ...... of Mycobacterium tuberculosis.
@ast
Protective immunity against tu ...... of Mycobacterium tuberculosis.
@en
Protective immunity against tu ...... of Mycobacterium tuberculosis.
@nl
prefLabel
Protective immunity against tu ...... of Mycobacterium tuberculosis.
@ast
Protective immunity against tu ...... of Mycobacterium tuberculosis.
@en
Protective immunity against tu ...... of Mycobacterium tuberculosis.
@nl
P2093
P2860
P356
P1476
Protective immunity against tu ...... of Mycobacterium tuberculosis.
@en
P2093
P2860
P304
P356
10.1073/PNAS.92.5.1530
P407
P577
1995-02-01T00:00:00Z