The mechanistic basis for noncompetitive ibogaine inhibition of serotonin and dopamine transporters
about
Behavioral, biological, and chemical perspectives on atypical agents targeting the dopamine transporterNonclassical pharmacology of the dopamine transporter: atypical inhibitors, allosteric modulators, and partial substratesNPS: Medical Consequences Associated with Their IntakeLigand induced conformational changes of the human serotonin transporter revealed by molecular dynamics simulationsStructure and regulatory interactions of the cytoplasmic terminal domains of serotonin transporter.Novel psychoactive substances of interest for psychiatry.Two Na+ Sites Control Conformational Change in a Neurotransmitter Transporter HomologMechanism of Paroxetine (Paxil) Inhibition of the Serotonin Transporter.An Ethical Exploration of Barriers to Research on Controlled Drugs.Pharmacological examination of trifluoromethyl ring-substituted methcathinone analogsControl of serotonin transporter phosphorylation by conformational state.Emulating proton-induced conformational changes in the vesicular monoamine transporter VMAT2 by mutagenesis.Evidence for a role of transporter-mediated currents in the depletion of brain serotonin induced by serotonin transporter substrates.Designing modulators of 5-hydroxytryptamine signaling to treat abuse disorders.Ibogaine and addiction in the animal model, a systematic review and meta-analysis.Electrophysiological Actions of Synthetic Cathinones on Monoamine Transporters.Herbal Highs: Review on Psychoactive Effects and Neuropharmacology.Electrogenic Binding of Intracellular Cations Defines a Kinetic Decision Point in the Transport Cycle of the Human Serotonin Transporter.Pharmacological Chaperones of the Dopamine Transporter Rescue Dopamine Transporter Deficiency Syndrome Mutations in Heterologous Cells.Biophysical Approaches to the Study of LeuT, a Prokaryotic Homolog of Neurotransmitter Sodium Symporters.Functional Rescue of a Misfolded Drosophila melanogaster Dopamine Transporter Mutant Associated with a Sleepless Phenotype by Pharmacological Chaperones.Conformational state interactions provide clues to the pharmacochaperone potential of serotonin transporter partial substrates.A quantitative model of amphetamine action on the 5-HT transporter.The N Terminus Specifies the Switch between Transport Modes of the Human Serotonin Transporter.A salt bridge linking the first intracellular loop with the C terminus facilitates the folding of the serotonin transporter.Dual Action of Zn2+ on the Transport Cycle of the Dopamine Transporter.A cytosolic relay of heat shock proteins HSP70-1A and HSP90β monitors the folding trajectory of the serotonin transporter.A combined approach using transporter-flux assays and mass spectrometry to examine psychostimulant street drugs of unknown content.A dualistic conformational response to substrate binding in the human serotonin transporter reveals a high affinity state for serotonin.Pharmacochaperoning in a Drosophila model system rescues human dopamine transporter variants associated with infantile/juvenile parkinsonism.Relax, Cool Down and Scaffold: How to Restore Surface Expression of Folding-Deficient Mutant GPCRs and SLC6 Transporters.SLC6 Transporter Folding Diseases and Pharmacochaperoning.A kinetic account for amphetamine-induced monoamine release.A label-free approach to detect ligand binding to cell surface proteins in real time.The ins and outs of vesicular monoamine transporters
P2860
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P2860
The mechanistic basis for noncompetitive ibogaine inhibition of serotonin and dopamine transporters
description
2012 nî lūn-bûn
@nan
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
The mechanistic basis for nonc ...... onin and dopamine transporters
@ast
The mechanistic basis for nonc ...... onin and dopamine transporters
@en
The mechanistic basis for nonc ...... onin and dopamine transporters
@nl
type
label
The mechanistic basis for nonc ...... onin and dopamine transporters
@ast
The mechanistic basis for nonc ...... onin and dopamine transporters
@en
The mechanistic basis for nonc ...... onin and dopamine transporters
@nl
prefLabel
The mechanistic basis for nonc ...... onin and dopamine transporters
@ast
The mechanistic basis for nonc ...... onin and dopamine transporters
@en
The mechanistic basis for nonc ...... onin and dopamine transporters
@nl
P2093
P2860
P50
P356
P1476
The mechanistic basis for nonc ...... onin and dopamine transporters
@en
P2093
Gary Rudnick
Simon Bulling
Walter Sandtner
Yuan-Wei Zhang
P2860
P304
18524-18534
P356
10.1074/JBC.M112.343681
P407
P50
P577
2012-03-26T00:00:00Z