The unfolded protein response in nutrient sensing and differentiation.
about
Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1 alpha to the endoplasmic reticulum and promotes dephosphorylation of the alpha subunit of eukaryotic translation initiation factor 2The unfolded protein response induces the angiogenic switch in human tumor cells through the PERK/ATF4 pathwayStructure and intermolecular interactions of the luminal dimerization domain of human IRE1alphaNck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translationDerlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradationEndoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3betaA ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of ParkinDifferential regulation of endoplasmic reticulum stress by protein tyrosine phosphatase 1B and T cell protein tyrosine phosphataseThe role of protease inhibitors in the pathogenesis of HIV-associated lipodystrophy: cellular mechanisms and clinical implicationsAtf4 regulates obesity, glucose homeostasis, and energy expenditureHuman cytomegalovirus infection alters the substrate specificities and rapamycin sensitivities of raptor- and rictor-containing complexesHomocysteine in Renal InjuryThe endoplasmic reticulum: structure, function and response to cellular signalingDNAJs: more than substrate delivery to HSPASpliced leader RNA silencing (SLS) - a programmed cell death pathway in Trypanosoma brucei that is induced upon ER stressXenobiotic perturbation of ER stress and the unfolded protein responseProtein tyrosine phosphatase 1B deficiency potentiates PERK/eIF2α signaling in brown adipocytesDcr2 targets Ire1 and downregulates the unfolded protein response in Saccharomyces cerevisiaeUnfolded protein response regulates yeast small GTPase Arl1p activation at late Golgi via phosphorylation of Arf GEF Syt1p.The unfolded protein response represses differentiation through the RPD3-SIN3 histone deacetylasePossible Integrative Actions of Leptin and Insulin Signaling in the Hypothalamus Targeting Energy HomeostasisNatural history of β-cell adaptation and failure in type 2 diabetesA DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effectProtein carbonylation, cellular dysfunction, and disease progressionRoles of molecular chaperones in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD)Inhibition of soluble epoxide hydrolase attenuates hepatic fibrosis and endoplasmic reticulum stress induced by carbon tetrachloride in miceHDAC and Proteasome Inhibitors Synergize to Activate Pro-Apoptotic Factors in Synovial SarcomaIMPACT, a protein preferentially expressed in the mouse brain, binds GCN1 and inhibits GCN2 activationActivating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress responseProtein Kinase RNA-Like Endoplasmic Reticulum Kinase-Mediated Bcl-2 Protein Phosphorylation Contributes to Evodiamine-Induced Apoptosis of Human Renal Cell Carcinoma CellsPERK and GCN2 contribute to eIF2alpha phosphorylation and cell cycle arrest after activation of the unfolded protein response pathwayNck-dependent activation of extracellular signal-regulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress.Endoribonucleases--enzymes gaining spotlight in mRNA metabolism.Inhibition of the unfolded protein response by ricin a-chain enhances its cytotoxicity in mammalian cellsSeparation of sodiated isobaric disaccharides and trisaccharides using electrospray ionization-atmospheric pressure ion mobility-time of flight mass spectrometry.Inhibition of proliferation by PERK regulates mammary acinar morphogenesis and tumor formation.Loss of p24 function in Drosophila melanogaster causes a stress response and increased levels of NF-kappaB-regulated gene products.A role for the unfolded protein response (UPR) in virulence and antifungal susceptibility in Aspergillus fumigatus.Global prediction of tissue-specific gene expression and context-dependent gene networks in Caenorhabditis elegans.The calpain, caspase 12, caspase 3 cascade leading to apoptosis is altered in F508del-CFTR expressing cells
P2860
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P2860
The unfolded protein response in nutrient sensing and differentiation.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The unfolded protein response in nutrient sensing and differentiation.
@ast
The unfolded protein response in nutrient sensing and differentiation.
@en
The unfolded protein response in nutrient sensing and differentiation.
@nl
type
label
The unfolded protein response in nutrient sensing and differentiation.
@ast
The unfolded protein response in nutrient sensing and differentiation.
@en
The unfolded protein response in nutrient sensing and differentiation.
@nl
prefLabel
The unfolded protein response in nutrient sensing and differentiation.
@ast
The unfolded protein response in nutrient sensing and differentiation.
@en
The unfolded protein response in nutrient sensing and differentiation.
@nl
P2093
P356
P1476
The unfolded protein response in nutrient sensing and differentiation.
@en
P2093
Chuan Yin Liu
Donalyn Scheuner
Kyungho Lee
Martin Schröder
Randal J Kaufman
Stacey M Arnold
Xiaohua Shen
P2888
P304
P356
10.1038/NRM829
P577
2002-06-01T00:00:00Z
P6179
1038345451